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We investigate adaptive strategies to robustly and optimally control the COVID-19 pandemic via social distancing measures based on the example of Germany. Our goal is to minimize the number of fatalities over the course of two years without…

Populations and Evolution · Quantitative Biology 2021-02-09 Johannes Köhler , Lukas Schwenkel , Anne Koch , Julian Berberich , Patricia Pauli , Frank Allgöwer

Attempts to control the epidemic spread of COVID19 in the different countries often involve imposing restrictions to the mobility of citizens. Recent examples demonstrate that the effectiveness of these policies strongly depends on the…

Physics and Society · Physics 2020-07-10 Alejandro Carballosa , Mariamo Mussa-Juane , Alberto P. Muñuzuri

The interpretation of sampling data plays a crucial role in policy response to the spread of a disease during an epidemic, such as the COVID-19 epidemic of 2020. However, this is a non-trivial endeavor due to the complexity of real world…

Populations and Evolution · Quantitative Biology 2020-07-30 James D. Brunner , Nicholas Chia

While several non-pharmacological measures have been implemented for a few months in an effort to slow the coronavirus disease (COVID-19) pandemic in the United States, the disease remains a danger in a number of counties as restrictions…

Physics and Society · Physics 2021-04-06 Chao Fan , Xiangqi Jiang , Ronald Lee , Ali Mostafavi

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

Optimization and Control · Mathematics 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

The experience of Singapur and South Korea makes it clear that under certain circumstances massive testing is an effective way for containing the advance of the COVID-19. In this paper, we propose a modified SEIR model which takes into…

Applications · Statistics 2020-12-24 José Luis Sainz-Pardo , José Valero

Quarantine measure is a commonly used non-pharmaceutical intervention during the outbreak of infectious diseases. A key problem for implementing quarantine measure is to determine the duration of quarantine. In this paper, a policy with…

Applications · Statistics 2023-09-26 Ruoyu Wang , Qihua Wang

Epidemiological models are an important tool in coping with epidemics, as they offer a forecast, even if often simplistic, of the behavior of the disease in the population. This allows responsible health agencies to organize themselves and…

Populations and Evolution · Quantitative Biology 2023-08-03 Eliza Maria Ferreira , Ricardo Edem Ferreira , Chiara Mocenni

Pooled testing offers an efficient solution to the unprecedented testing demands of the COVID-19 pandemic, although with potentially lower sensitivity and increased costs to implementation in some settings. Assessments of this trade-off…

Applications · Statistics 2021-07-13 Saskia Comess , Hannah Wang , Susan Holmes , Claire Donnat

Motivated by COVID-19, we develop and analyze a simple stochastic model for a disease spread in human population. We track how the number of infected and critically ill people develops over time in order to estimate the demand that is…

Populations and Evolution · Quantitative Biology 2022-05-10 Jakub Svoboda , Josef Tkadlec , Andreas Pavlogiannis , Krishnendu Chatterjee , Martin A. Nowak

National responses to the Covid-19 pandemic varied markedly across countries, from business-as-usual to complete shutdowns. Policies aimed at disrupting the viral transmission cycle and preventing the healthcare system from being…

Populations and Evolution · Quantitative Biology 2021-10-27 Arash Saeidpour , Pejman Rohani

We approach the development of models and control strategies of susceptible-infected-susceptible (SIS) epidemic processes from the perspective of marked temporal point processes and stochastic optimal control of stochastic differential…

Optimization and Control · Mathematics 2018-12-04 Lars Lorch , Abir De , Samir Bhatt , William Trouleau , Utkarsh Upadhyay , Manuel Gomez-Rodriguez

I employ a simple mathematical model of an epidemic process to evaluate how four basic quantities: the reproduction number (R), the numbers of sensitive (S) and infectious individuals(I), and total community size (N) affect strategies to…

Populations and Evolution · Quantitative Biology 2020-05-08 Michael E. Hochberg

This paper addresses statistical modelling and forecasting of key indicators describing the severity of a developing pandemic, using routinely reported daily counts of infections, hospitalizations, deaths (both in and out of hospital), and…

Sample pooling consists in combining samples from multiple individuals into a single pool that is then tested using a unique test-kit. A positive test means that at least one individual within the pool is infected. Here, we propose an…

Quantitative Methods · Quantitative Biology 2021-03-18 Vincent Brault , Bastien Mallein , Jean-Francois Rupprecht

Recent Covid-19 pandemic has demonstrated the need of efficient epidemic outbreak management. We study the optimal control problem of minimizing the fraction of infected population by applying vaccination and treatment control strategies,…

Social and Information Networks · Computer Science 2021-12-07 Jagtap Kalyani Devendra , Kundan Kandhway

Intent of this research is to explore how mathematical models, specifically Susceptible-Infected-Removed (SIR) model, can be utilized to forecast peak outbreak timeline of COVID-19 epidemic amongst a population of interest starting from the…

Populations and Evolution · Quantitative Biology 2020-09-14 Amit Tewari

Epidemics such as COVID-19 pose serious threats to public health and our society, and it is critical to investigate effective methods to control the spread of epidemics over networks. Prior works on epidemic control often assume complete…

Artificial Intelligence · Computer Science 2023-10-13 Wenxiang Dong , Zhanjiang Chen , H. Vicky Zhao

Testing is an important part of tackling the COVID-19 pandemic. Availability of testing is a bottleneck due to constrained resources and effective prioritization of individuals is necessary. Here, we discuss the impact of different…

Machine Learning · Computer Science 2020-07-30 Hagit Grushka-Cohen , Raphael Cohen , Bracha Shapira , Jacob Moran-Gilad , Lior Rokach

Lately, concepts such as lockdown, quarantine, and social distancing have become very relevant since they have been associated with essential measures in the prevention and mitigation of COVID-19. While some conclusions about the…

Physics and Society · Physics 2023-04-04 Eric Rozan , Sebastian Bouzat , Marcelo N Kuperman