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Non-invasive morphological assessment is the cornerstone of oocyte and embryo selection in assisted reproductive technology, yet clinical practice remains limited by two-dimensional, qualitative microscopy. While three-dimensional (3D)…

By integrating a phase-only Spatial Light Modulator (SLM) into the illumination arm of a cylindrical-lens-based Selective Plane Illumination Microscope (SPIM), we have created a versatile system able to deliver high quality images by…

Biological Physics · Physics 2018-08-10 Chiara Garbellotto , Jonathan M. Taylor

Microscopy has been key to tremendous advances in science, technology, and medicine, revealing structure and dynamics across time and length scales. However, combining high spatial and temporal resolution in a non-invasive, label-free…

Quantitative imaging of subcellular processes in living embryos, stem-cell systems, and organoid models requires microscopy platforms that combine high spatial resolution, fast volumetric acquisition, long-term stability, and minimal…

Quantitative Methods · Quantitative Biology 2025-12-30 Armin Shoushtarizadeh , Michele Cerminara , Corinne Chureau , Leah Friedman , Deepthi Kailash , Thomas Gregor

p-Conjugated materials, including small molecules and polymers, are attracting substantial attention as novel gain media in semiconductor lasers; they offer many potential advantages not achievable with conventional inorganic…

Materials Science · Physics 2007-05-23 Yun Tian , Zhengqing Gan , Zhaoqun Zhou , Ji-hun Kang , Q-Han Park , David W. Lynch , Joseph Shinar

Non-invasive stimulation of small, variably shaped brain sub-regions is crucial for advancing our understanding of brain functions. Current ultrasound neuromodulation faces two significant trade-offs when targeting brain sub-regions:…

Neurons and Cognition · Quantitative Biology 2025-07-09 Yueming Li , Guo Chen , Tiago R. Oliveira , Nick Todd , Yong-Zhi Zhang , Carolyn Marar , Nan Zheng , Lu Lan , Nathan McDannold , Ji-Xin Cheng , Chen Yang

Achieving high-fidelity, compact RGBD imaging presents a dual challenge: conventional compact optics struggle with RGB sharpness across the entire depth-of-field, while software-only Monocular Depth Estimation (MDE) is an ill-posed problem…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Zongxi Yu , Xiaolong Qian , Shaohua Gao , Qi Jiang , Yao Gao , Kailun Yang , Kaiwei Wang

Three-dimensional (3D) fluorescence imaging provides a vital approach for study of biological tissues with intricate structures, and optical sectioning structured illumination microscopy (OS-SIM) stands out for its high imaging speed, low…

Organic Light Emitting Diodes (OLED) have experienced vast attention in the scientific literature as the leading contender for the next generation of electronic lighting technology. However, while research continues to push the limit for…

Applied Physics · Physics 2019-08-02 Sahadev Somasundaram

Oblique angle deposition (OAD) is a nanostructuration method widely used to tune the optical properties of thin films. The introduction of porosity controlled by the deposition angle is used to develop the architecture of each layer and…

The intricate nature of the brain necessitates the application of advanced probing techniques to comprehensively study and understand its working mechanisms. Neurophotonics offers minimally invasive methods to probe the brain using optics…

In the intact brain, neural activity can be recorded using sensing electrodes and manipulated using light stimulation. Silicon probes with integrated electrodes and micro-LEDs enable the detection and control of neural activity using a…

Signal Processing · Electrical Eng. & Systems 2022-11-28 Alexander Tarnavsky Eitan , Shirly Someck , Mario Zajac , Eran Socher , Eran Stark

Organic light-emitting diodes (OLEDs) have successfully entered the display market and continue to be attractive for many other applications. As state-of-the-art OLEDs can reach an internal quantum efficiency (IQE) of almost 100 %, light…

Three dimensional Polarized Light Imaging (3D-PLI) is an optical technique which allows mapping the spatial fiber architecture of fibrous postmortem tissues, at sub-millimeter resolutions. Here, we propose an analytical and fast approach to…

Medical Physics · Physics 2020-12-18 A. Alimi , S. Deslauriers-Gauthier , F. Matuschke , A. Müller , S. E. A. Muenzing , M. Axer , R. Deriche

Existing computational spectral imaging systems typically rely on coded aperture and beam splitters that block a substantial fraction of incident light, degrading reconstruction quality under light-starved conditions. To address this…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Jiuyun Zhang , Zhan Shi , Linsen Chen , Xun Cao

We report the implementation of a fully on-chip, lensless microscopy technique termed optofluidic ptychography. This imaging modality complements the miniaturization provided by microfluidics and allows the integration of ptychographic…

Instrumentation and Detectors · Physics 2021-12-21 Pengming Song , Chengfei Guo , Shaowei Jiang , Tianbo Wang , Patrick Hu , Derek Hu , Zibang Zhang , Bin Feng , Guoan Zheng

We present a pulsed laser deposition (PLD) system that can monitor growth by simultaneously using in situ optical spectroscopic ellipsometry (SE) and reflection high-energy electron diffraction (RHEED). The RHEED precisely monitors the…

Materials Science · Physics 2013-09-09 J. H. Gruenewald , J. Nichols , S. S. A. Seo

In this technical review we give an introduction to optical spectroscopy for layered materials as a powerful, non-invasive tool to access details of the electronic band structure and crystal quality. Potential applications in photonics and…

Materials Science · Physics 2020-12-18 Shivangi Shree , Ioannis Paradisanos , Xavier Marie , Cedric Robert , Bernhard Urbaszek

We present a novel extended-focus optical coherence microscope (OCM) attaining 0.7 {\mu}m axial and 0.4 {\mu}m lateral resolution maintained over a depth of 40 {\mu}m, while preserving the advantages of Fourier domain OCM. Our method uses…

Quantum memory is the core device for the construction of large-scale quantum networks. For scalable and convenient practical applications, integrated optical memories, especially on-chip optical memories, are crucial requirements because…

Quantum Physics · Physics 2020-12-07 Tian-Xiang Zhu , Chao Liu , Liang Zheng , Zong-Quan Zhou , Chuan-Feng Li , Guang-Can Guo
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