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We present a non-invasive, label-free method of imaging blood cells flowing through human capillaries in vivo using oblique back-illumination capillaroscopy (OBC). Green light illumination allows simultaneous phase and absorption contrast,…
Photodiodes are widely used to convert lights into electrical signals. The conventional silicon (Si) based photodiodes boast high photoelectric conversion efficiency and detectivity. However, in general, inorganic-based photodiodes have low…
The application of solution-processable graphene oxide (GO) as hole injection layer in organic light-emitting diodes (OLEDs) is demonstrated. High luminance of over 53,000 cd m-2 is obtained at only 10 V. The results will unlock a route of…
Optogenetics has emerged as a powerful tool for disease modeling, enabling precise control of cellular activities through light stimulation and providing a valuable insights into disease mechanisms and therapeutic possibilities. Innovative…
3D-Polarized Light Imaging (3D-PLI) is a neuroimaging technique used to study the structural connectivity of the human brain at the meso- and microscale. In 3D-PLI, the complex nerve fiber architecture of the brain is characterized by 3D…
Objective: Optogenetic manipulations of excitable cells enable activating or silencing specific types of neurons. By expressing two types of exogenous proteins, a single neuron can be depolarized using light of one wavelength and…
Clinical measurement of a patient's axial eye length is emerging as a crucial approach to track progression and monitor management of myopia. However, the preferred method for such measurements is swept-source OCT, whose cost prohibits…
The fabrication of a high-quality POLED (Polymeric Organic Light Emitting Diode) display requires the deposition of identical, uniform fluid films into a large number of shallow recessed regions that form a regular array of pixels on a…
The on-chip creation of coherent light at visible wavelengths is crucial to field-level deployment of spectroscopy and metrology systems. Although on-chip lasers have been implemented in specific cases, a general solution that is not…
Electroencephalography (EEG) analysis extracts critical information from brain signals, which has provided fundamental support for various applications, including brain-disease diagnosis and brain-computer interface. However, the real-time…
Optical communication achieves high fanout and short delay advantageous for information integration in neural systems. Superconducting detectors enable signaling with single photons for maximal energy efficiency. We present designs of…
Optical parametric oscillation (OPO) in Kerr microresonators can efficiently transfer near-infrared laser light into the visible spectrum. To date, however, chromatic dispersion has mostly limited output wavelengths to >560 nm, and robust…
Silicon p-n junction diodes emit low-intensity, broad-spectrum light near 1120 nm in forward bias and between 400-900 nm in reverse bias (avalanche). For the first time, we experimentally achieve optical absorption sensing of pigment in…
Oxygen plasma is a widely used treatment to change the surface properties of organic layers. This treatment is particularly interesting to enable the deposition from solution of poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate)…
We describe a teaching-lab experiment that applies basic optical spectroscopy to examine the physics of semiconductor diode lasers. By using a low-power visible laser, this experiment is suitable for use in an open lab environment, where…
In radiation oncology, inter-fractional dosimetry is often performed with luminescent dosimeters to verify the accurate delivery of a plan and ensure patient safety. Optically stimulated luminescent detectors (OSLDs) are the most commonly…
Microstructured optical waveguides (MOW) are of great interest for chemical and biological sensing. Due to the high overlap between a guiding light mode and an analyte filling of one or several fiber capillaries, such systems are able to…
Neural networks have proven effective for solving many difficult computational problems. Implementing complex neural networks in software is very computationally expensive. To explore the limits of information processing, it will be…
Deep learning has recently gained high interest in ophthalmology, due to its ability to detect clinically significant features for diagnosis and prognosis. Despite these significant advances, little is known about the ability of various…
All optical diodes (AODs) play an important role in quantum optics and information processing, in which the information is encoded by photons. Only circularly polarized lights are able to carry the spin states of photons, which has been…