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Fully convolutional deep neural networks carry out excellent potential for fast and accurate image segmentation. One of the main challenges in training these networks is data imbalance, which is particularly problematic in medical imaging…

Computer Vision and Pattern Recognition · Computer Science 2017-06-20 Seyed Sadegh Mohseni Salehi , Deniz Erdogmus , Ali Gholipour

Many loss functions have been derived from cross-entropy loss functions such as large-margin softmax loss and focal loss. The large-margin softmax loss makes the classification more rigorous and prevents overfitting. The focal loss…

Computer Vision and Pattern Recognition · Computer Science 2023-02-10 Jiajie Chen

In medical imaging, segmentation models have known a significant improvement in the past decade and are now used daily in clinical practice. However, similar to classification models, segmentation models are affected by adversarial attacks.…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Othmane Laousy , Alexandre Araujo , Guillaume Chassagnon , Nikos Paragios , Marie-Pierre Revel , Maria Vakalopoulou

Recent studies have demonstrated the superior performance of introducing ``scan-wise" contrast labels into contrastive learning for multi-organ segmentation on multi-phase computed tomography (CT). However, such scan-wise labels are…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Ho Hin Lee , Yucheng Tang , Han Liu , Yubo Fan , Leon Y. Cai , Qi Yang , Xin Yu , Shunxing Bao , Yuankai Huo , Bennett A. Landman

Deep learning-based medical image segmentation is increasingly used to support clinical diagnosis and develop new treatment strategies. However, model performance remains limited by the scarcity of high-quality annotated data and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Nathan Molinier , Hendrik Möller , Thomas Dagonneau , Anna Curto-Vilalta , Robert Graf , Matan Atad , Daniel Rueckert , Jan S. Kirschke , Julien Cohen-Adad

The Dice Similarity Coefficient (DSC) is the current de facto standard to determine agreement between a reference segmentation and one generated by manual / auto-contouring approaches. This metric is useful for non-spatially important…

Medical Physics · Physics 2024-10-29 Lucas McCullum , Kareem A. Wahid , Barbara Marquez , Clifton D. Fuller

Deep neural networks for medical image segmentation are often overconfident, compromising both reliability and clinical utility. In this work, we propose differentiable formulations of marginal L1 Average Calibration Error (mL1-ACE) as an…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Theodore Barfoot , Luis C. Garcia-Peraza-Herrera , Samet Akcay , Ben Glocker , Tom Vercauteren

Segmentation of Hypoxic-Ischemic Encephalopathy (HIE) lesions in neonatal MRI is a crucial but challenging task due to diffuse multifocal lesions with varying volumes and the limited availability of annotated HIE lesion datasets. Using the…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Annayah Usman , Abdul Haseeb , Tahir Syed

In this paper, we present a novel region-based segmentation method for cortical spreading depressions in 2-photon microscopy images. Fluorescent microscopy has become an important tool in neuroscience, but segmentation approaches are…

Image and Video Processing · Electrical Eng. & Systems 2019-02-04 M. Filip Sluzewski , Petr Tvrdik , Scott T. Acton

Image segmentation, the process of dividing images into meaningful regions, is critical in medical applications for accurate diagnosis, treatment planning, and disease monitoring. Although manual segmentation by healthcare professionals…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Salma J. Ahmed , Emad A. Mohammed , Azam Asilian Bidgoli

Performance metrics for medical image segmentation models are used to measure the agreement between the reference annotation and the predicted segmentation. Usually, overlap metrics, such as the Dice, are used as a metric to evaluate the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Sophie Ostmeier , Brian Axelrod , Jeroen Bertels , Fabian Isensee , Maarten G. Lansberg , Soren Christensen , Gregory W. Albers , Li-Jia Li , Jeremy J. Heit

Objective: Overlapping measures are often utilized to quantify the similarity between two binary regions. However, modern segmentation algorithms output a probability or confidence map with continuous values in the zero-to-one interval.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-27 Reuben R Shamir , Yuval Duchin , Jinyoung Kim , Guillermo Sapiro , Noam Harel

Deep neural networks for medical image segmentation often produce overconfident results misaligned with empirical observations. Such miscalibration, challenges their clinical translation. We propose to use marginal L1 average calibration…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Theodore Barfoot , Luis Garcia-Peraza-Herrera , Ben Glocker , Tom Vercauteren

While deep learning has achieved significant advances in accuracy for medical image segmentation, its benefits for deformable image registration have so far remained limited to reduced computation times. Previous work has either focused on…

Computer Vision and Pattern Recognition · Computer Science 2018-12-06 Alessa Hering , Sven Kuckertz , Stefan Heldmann , Mattias Heinrich

Fully-convolutional neural networks have achieved superior performance in a variety of image segmentation tasks. However, their training requires laborious manual annotation of large datasets, as well as acceleration by parallel processors…

Neural and Evolutionary Computing · Computer Science 2018-11-29 Blaine Rister , Darvin Yi , Kaushik Shivakumar , Tomomi Nobashi , Daniel L. Rubin

Deep neural networks have demonstrated very promising performance on accurate segmentation of challenging organs (e.g., pancreas) in abdominal CT and MRI scans. The current deep learning approaches conduct pancreas segmentation by…

Computer Vision and Pattern Recognition · Computer Science 2017-07-19 Jinzheng Cai , Le Lu , Yuanpu Xie , Fuyong Xing , Lin Yang

Medical experts often manually segment images to obtain diagnostic statistics and discard the resulting annotations. We aim to train segmentation models to alleviate this burden, but constrained to the retained summary statistics (e.g., the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Omkar Kulkarni , Edward Raff , Tim Oates

Manual segmentation of medical images is labor intensive and especially challenging for images with poor contrast or resolution. The presence of disease exacerbates this further, increasing the need for an automated solution. To this…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Selena Huisman , Matteo Maspero , Marielle Philippens , Joost Verhoeff , Szabolcs David

Medical image segmentation has played an important role in medical analysis and widely developed for many clinical applications. Deep learning-based approaches have achieved high performance in semantic segmentation but they are limited to…

Image and Video Processing · Electrical Eng. & Systems 2020-12-07 Ngan Le , Trung Le , Kashu Yamazaki , Toan Duc Bui , Khoa Luu , Marios Savides

The anatomical location of imaging features is of crucial importance for accurate diagnosis in many medical tasks. Convolutional neural networks (CNN) have had huge successes in computer vision, but they lack the natural ability to…

Computer Vision and Pattern Recognition · Computer Science 2016-11-01 Mohsen Ghafoorian , Nico Karssemeijer , Tom Heskes , Inge van Uden , Clara Sanchez , Geert Litjens , Frank-Erik de Leeuw , Bram van Ginneken , Elena Marchiori , Bram Platel
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