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Artificial intelligence (AI)-based methods are showing substantial promise in segmenting oncologic positron emission tomography (PET) images. For clinical translation of these methods, assessing their performance on clinically relevant…

Medical Physics · Physics 2023-04-19 Ziping Liu , Joyce C. Mhlanga , Barry A. Siegel , Abhinav K. Jha

Today, deep convolutional neural networks (CNNs) have demonstrated state-of-the-art performance for medical image segmentation, on various imaging modalities and tasks. Despite early success, segmentation networks may still generate…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Rosana El Jurdi , Caroline Petitjean , Veronika Cheplygina , Paul Honeine , Fahed Abdallah

We propose a novel approach to image segmentation based on combining implicit spline representations with deep convolutional neural networks. This is done by predicting the control points of a bivariate spline function whose zero-set…

Image and Video Processing · Electrical Eng. & Systems 2021-03-22 Oliver J. D. Barrowclough , Georg Muntingh , Varatharajan Nainamalai , Ivar Stangeby

Background: In the field of radiology and radiotherapy, accurate delineation of tissues and organs plays a crucial role in both diagnostics and therapeutics. While the gold standard remains expert-driven manual segmentation, many automatic…

Quantitative Methods · Quantitative Biology 2025-08-14 Szuzina Fazekas , Bettina Katalin Budai , Viktor Bérczi , Pál Maurovich-Horvat , Zsolt Vizi

Pancreatic cancer, which has a low survival rate, is one of the most challenging cancers to diagnose and treat effectively. Early detection through abdominal computed tomography (CT) scans is crucial, yet complicated by the pancreas'…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Xubei Zhang , Mikhail Y. Shalaginov , Tingying Helen Zeng

We propose a generalized focal loss function based on the Tversky index to address the issue of data imbalance in medical image segmentation. Compared to the commonly used Dice loss, our loss function achieves a better trade off between…

Computer Vision and Pattern Recognition · Computer Science 2018-10-19 Nabila Abraham , Naimul Mefraz Khan

The medical image processing field often encounters the critical issue of scarce annotated data. Transfer learning has emerged as a solution, yet how to select an adequate source task and effectively transfer the knowledge to the target…

Image and Video Processing · Electrical Eng. & Systems 2024-10-10 Jingyun Yang , Jingge Wang , Guoqing Zhang , Yang Li

Segmentation tasks in medical imaging are inherently ambiguous: the boundary of a target structure is oftentimes unclear due to image quality and biological factors. As such, predicted segmentations from deep learning algorithms are…

Image and Video Processing · Electrical Eng. & Systems 2019-11-18 Katharina Hoebel , Ken Chang , Jay Patel , Praveer Singh , Jayashree Kalpathy-Cramer

Albeit the Dice loss is one of the dominant loss functions in medical image segmentation, most research omits a closer look at its derivative, i.e. the real motor of the optimization when using gradient descent. In this paper, we highlight…

Computer Vision and Pattern Recognition · Computer Science 2022-11-10 Sofie Tilborghs , Jeroen Bertels , David Robben , Dirk Vandermeulen , Frederik Maes

Automated segmentation of medical imaging is of broad interest to clinicians and machine learning researchers alike. The goal of segmentation is to increase efficiency and simplicity of visualization and quantification of regions of…

Image and Video Processing · Electrical Eng. & Systems 2020-06-04 Shruti Jadon , Owen P. Leary , Ian Pan , Tyler J. Harder , David W. Wright , Lisa H. Merck , Derek L. Merck

Although numerous improvements have been made in the field of image segmentation using convolutional neural networks, the majority of these improvements rely on training with larger datasets, model architecture modifications, novel loss…

Computer Vision and Pattern Recognition · Computer Science 2019-07-11 Saied Asgari Taghanaki , Kumar Abhishek , Ghassan Hamarneh

The Jaccard index, also known as Intersection-over-Union (IoU), is one of the most critical evaluation metrics in image semantic segmentation. However, direct optimization of IoU score is very difficult because the learning objective is…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Litao Yu , Zhibin Li , Min Xu , Yongsheng Gao , Jiebo Luo , Jian Zhang

Dynamic contrast-enhanced (DCE) cardiac magnetic resonance imaging (CMRI) is a widely used modality for diagnosing myocardial blood flow (perfusion) abnormalities. During a typical free-breathing DCE-CMRI scan, close to 300 time-resolved…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Dilek M. Yalcinkaya , Khalid Youssef , Bobak Heydari , Orlando Simonetti , Rohan Dharmakumar , Subha Raman , Behzad Sharif

Over the last decade, electron microscopy has improved up to a point that generating high quality gigavoxel sized datasets only requires a few hours. Automated image analysis, particularly image segmentation, however, has not evolved at the…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Joris Roels , Yvan Saeys

Manual segmentation is used as the gold-standard for evaluating neural networks on automated image segmentation tasks. Due to considerable heterogeneity in shapes, colours and textures, demarcating object boundaries is particularly…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Michael Yeung , Guang Yang , Evis Sala , Carola-Bibiane Schönlieb , Leonardo Rundo

Automatic image segmentation is a critical component of medical image analysis, and hence quantifying segmentation performance is crucial. Challenges in medical image segmentation are mainly due to spatial variations of regions to be…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Ammu R , Neelam Sinha

Cardiac magnetic resonance (CMR) is used extensively in the diagnosis and management of cardiovascular disease. Deep learning methods have proven to deliver segmentation results comparable to human experts in CMR imaging, but there have…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Gerard Snaauw , Dong Gong , Gabriel Maicas , Anton van den Hengel , Wiro J. Niessen , Johan Verjans , Gustavo Carneiro

Machine learning algorithms underpin modern diagnostic-aiding software, which has proved valuable in clinical practice, particularly in radiology. However, inaccuracies, mainly due to the limited availability of clinical samples for…

This paper deals with segmentation of organs at risk (OAR) in head and neck area in CT images which is a crucial step for reliable intensity modulated radiotherapy treatment. We introduce a convolution neural network with encoder-decoder…

Computer Vision and Pattern Recognition · Computer Science 2018-12-07 Oldřich Kodym , Michal Španěl , Adam Herout

Neural networks for automated image segmentation are typically trained to achieve maximum accuracy, while less attention has been given to the calibration of their confidence scores. However, well-calibrated confidence scores provide…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Axel-Jan Rousseau , Thijs Becker , Jeroen Bertels , Matthew B. Blaschko , Dirk Valkenborg