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Single-particle imaging experiments of biomolecules at x-ray free-electron lasers (XFELs) require processing of hundreds of thousands (or more) of images that contain very few x-rays. Each low-flux image of the diffraction pattern is…

Instrumentation and Detectors · Physics 2012-03-16 Hugh T. Philipp , Kartik Ayyer , Mark W. Tate , Veit Elser , Sol M. Gruner

Semantic segmentation of electron microscopy (EM) images of biological samples remains a challenge in the life sciences. EM data captures details of biological structures, sometimes with such complexity that even human observers can find it…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Sheida Rahnamai Kordasiabi , Damian Dalle Nogare , Florian Jug

High-temperature superconductor $Bi_{2}Sr_{2}CaCu_{2}O_{8}+x$ has been investigated by the high-resolution electron microscope (HREM) and the photodensitometric technique in order to resolve the sub-atomic shifts in the modulated structure.…

Chaotic Dynamics · Physics 2007-05-23 D. Kunstelj , M. Martinis , A. Knežević

We demonstrate a significant resolution enhancement beyond the conventional limit in multiphoton microscopy (MPM) using saturated excitation of fluorescence. Our technique achieves super-resolved imaging by temporally modulating the…

We present an ``equation-free'' multiscale approach to the simulation of unsteady diffusion in a random medium. The diffusivity of the medium is modeled as a random field with short correlation length, and the governing equations are cast…

Numerical Analysis · Mathematics 2007-05-23 Dongbin Xiu , Ioannis Kevrekidis

Image super-resolution (SR) has attracted increasing attention due to its wide applications. However, current SR methods generally suffer from over-smoothing and artifacts, and most work only with fixed magnifications. This paper introduces…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Sicheng Gao , Xuhui Liu , Bohan Zeng , Sheng Xu , Yanjing Li , Xiaoyan Luo , Jianzhuang Liu , Xiantong Zhen , Baochang Zhang

In high-contrast space-based coronagraphs, one of the main limiting factors for imaging the dimmest exoplanets is the time varying nature of the residual starlight (speckles). Modern methods try to differentiate between the intensities of…

Instrumentation and Methods for Astrophysics · Physics 2019-09-04 Leonid Pogorelyuk , N. Jeremy Kasdin , Clarence W. Rowley

We provide a mathematical analysis of and a numerical framework for full-field optical coherence elastography, which has unique features including micron-scale resolution, real-time processing, and non-invasive imaging. We develop a novel…

Optimization and Control · Mathematics 2014-05-21 Habib Ammari , Elie Bretin , Pierre Millien , Laurent Seppecher , Jin-Keun Seo

Strong-field photoelectron holography denotes the interference of various electron paths in laser-induced ionization of atoms, leading to interference patterns in the final momentum distribution. For a quantitative description of holography…

Atomic Physics · Physics 2019-08-28 Simon Brennecke , Manfred Lein

Confocal laser endomicroscopy (CLE) is an advanced optical fluorescence technology undergoing assessment for applications in brain tumor surgery. Despite its promising potential, interpreting the unfamiliar gray tone images of fluorescent…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Mohammadhassan Izadyyazdanabadi , Evgenii Belykh , Michael Mooney , Nikolay Martirosyan , Jennifer Eschbacher , Peter Nakaji , Mark C. Preul , Yezhou Yang

Low voltage transmission electron microscopy (<=80 kV) has many applications in imaging beam-sensitive samples, such as metallic nanoparticles, which may become damaged at higher voltages. To improve resolution, spherical aberration can be…

Instrumentation and Detectors · Physics 2022-07-27 Frances Quigley , Patrick McBean , Peter O'Donovan , Jonathan J. P. Peters , Lewys Jones

The resolution of X-ray diffraction microscopy is limited by the maximum dose that can be delivered prior to sample damage. In the proposed Serial Crystallography method, the damage problem is addressed by distributing the total dose over…

3D super-resolution fluorescence microscopy typically requires sophisticated setups, sample preparation, or long measurements. A notable exception, SOFI, only requires recording a sequence of frames and no hardware modifications whatsoever…

Optics · Physics 2024-03-01 Pawel Szczypkowski , Monika Pawlowska , Radek Lapkiewicz

A microscopic theory for the luminescence of ordered semiconductors is modified to describe photoluminescence of strongly disordered semiconductors. The approach includes both diagonal disorder and the many-body Coulomb interaction. As a…

Disordered Systems and Neural Networks · Physics 2007-08-22 P. Bozsoki , M. Kira , W. Hoyer , T. Meier , I. Varga , P. Thomas , S. W. Koch

In the field of computer vision, the persistent presence of color bias, resulting from fluctuations in real-world lighting and camera conditions, presents a substantial challenge to the robustness of models. This issue is particularly…

Computer Vision and Pattern Recognition · Computer Science 2024-01-22 Yunpeng Gong , Jiaquan Li , Lifei Chen , Min Jiang

Fluorescence lifetime imaging microscopy (FLIM) provides detailed information about molecular interactions and biological processes. A major bottleneck for FLIM is image resolution at high acquisition speeds, due to the engineering and…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Valentin Kapitány , Areeba Fatima , Vytautas Zickus , Jamie Whitelaw , Ewan McGhee , Robert Insall , Laura Machesky , Daniele Faccio

We demonstrate experimentally quantum-inspired, spectral-domain intensity optical coherence tomography. We show that the technique allows for both axial resolution improvement and dispersion cancellation compared to conventional optical…

Optics · Physics 2015-03-16 Piotr Ryczkowski , Jari Turunen , Ari T. Friberg , Goëry Genty

I propose a superoscillation measurement method for subdiffraction incoherent optical sources, with potential applications in astronomy, remote sensing, fluorescence microscopy, and spectroscopy. The proposal, based on coherent optical…

Quantum Physics · Physics 2022-10-10 Mankei Tsang

Correlative light and electron microscopy is a powerful tool to study the internal structure of cells. It combines the mutual benefit of correlating light (LM) and electron (EM) microscopy information. However, the classical approach of…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Fengjiao Ma , Rainer Kaufmann , Jaroslaw Sedzicki , Zoltán Cseresnyés , Christoph Dehio , Stephanie Hoeppener , Marc Thilo Figge , Rainer Heintzmann

Fast and sensitive detector arrays enable image scanning microscopy (ISM), overcoming the trade-off between spatial resolution and signal-to-noise ratio (SNR) typical of confocal microscopy. However, current ISM approaches cannot provide…

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