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Neural networks are increasingly used to estimate parameters in quantitative MRI, in particular in magnetic resonance fingerprinting. Their advantages over the gold standard non-linear least square fitting are their superior speed and their…

Although the currently popular deep learning networks achieve unprecedented performance on some tasks, the human brain still has a monopoly on general intelligence. Motivated by this and biological implausibility of deep learning networks,…

Neurons and Cognition · Quantitative Biology 2019-09-10 Cengiz Pehlevan , Dmitri B. Chklovskii

Equilibrium systems are a powerful way to express neural computations. As special cases, they include models of great current interest in both neuroscience and machine learning, such as deep neural networks, equilibrium recurrent neural…

Machine Learning · Computer Science 2022-11-01 Alexander Meulemans , Nicolas Zucchet , Seijin Kobayashi , Johannes von Oswald , João Sacramento

Advances in optical and electrophysiological recording technologies have made it possible to record the dynamics of thousands of neurons, opening up new possibilities for interpreting and controlling large neural populations in behaving…

Neurons and Cognition · Quantitative Biology 2023-11-20 Fatih Dinc , Adam Shai , Mark Schnitzer , Hidenori Tanaka

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

Brains learn to represent information from a large set of stimuli, typically by weak supervision. Unsupervised learning is therefore a natural approach for exploring the design of biological neural networks and their computations.…

Neurons and Cognition · Quantitative Biology 2025-10-17 Roy Urbach , Elad Schneidman

Unsupervised learning permits the development of algorithms that are able to adapt to a variety of different data sets using the same underlying rules thanks to the autonomous discovery of discriminating features during training. Recently,…

Neural and Evolutionary Computing · Computer Science 2018-01-30 Yanis Bahroun , Andrea Soltoggio

Recent advances in machine learning have led to a surge in adoption of neural networks for various tasks, but lack of interpretability remains an issue for many others in which an understanding of the features influencing the prediction is…

Neural networks that can capture key principles underlying brain computation offer exciting new opportunities for developing artificial intelligence and brain-like computing algorithms. Such networks remain biologically plausible while…

Neural and Evolutionary Computing · Computer Science 2025-01-10 Naresh Ravichandran , Anders Lansner , Pawel Herman

The backpropagation algorithm is an invaluable tool for training artificial neural networks; however, because of a weight sharing requirement, it does not provide a plausible model of brain function. Here, in the context of a two-layer…

Neural and Evolutionary Computing · Computer Science 2020-12-01 Siavash Golkar , David Lipshutz , Yanis Bahroun , Anirvan M. Sengupta , Dmitri B. Chklovskii

Biological and artificial learning agents face numerous choices about how to learn, ranging from hyperparameter selection to aspects of task distributions like curricula. Understanding how to make these meta-learning choices could offer…

Neural and Evolutionary Computing · Computer Science 2024-07-16 Rodrigo Carrasco-Davis , Javier Masís , Andrew M. Saxe

Neural network models of early sensory processing typically reduce the dimensionality of streaming input data. Such networks learn the principal subspace, in the sense of principal component analysis (PCA), by adjusting synaptic weights…

Neurons and Cognition · Quantitative Biology 2015-05-18 Cengiz Pehlevan , Tao Hu , Dmitri B. Chklovskii

Biological cortical networks are potentially fully recurrent networks without any distinct output layer, where recognition may instead rely on the distribution of activity across its neurons. Because such biological networks can have rich…

Neurons and Cognition · Quantitative Biology 2022-11-14 Pakorn Uttayopas , Xiaoxiao Cheng , Udaya Bhaskar Rongala , Henrik Jörntell , Etienne Burdet

Inspired by the natural nervous system, synaptic plasticity rules are applied to train spiking neural networks with local information, making them suitable for online learning on neuromorphic hardware. However, when such rules are…

Neural and Evolutionary Computing · Computer Science 2022-02-28 J. Lu , J. J. Hagenaars , G. C. H. E. de Croon

Convolutional networks are ubiquitous in deep learning. They are particularly useful for images, as they reduce the number of parameters, reduce training time, and increase accuracy. However, as a model of the brain they are seriously…

Machine Learning · Computer Science 2022-01-19 Roman Pogodin , Yash Mehta , Timothy P. Lillicrap , Peter E. Latham

The idea that information-processing systems operate near criticality to enhance computational performance is supported by scaling signatures in brain activity. However, external signals raise the question of whether this behavior is…

Neurons and Cognition · Quantitative Biology 2026-02-10 Rubén Calvo , Carles Martorell , Adrián Roig , Miguel A. Muñoz

The state-of-the art machine learning approach to training deep neural networks, backpropagation, is implausible for real neural networks: neurons need to know their outgoing weights; training alternates between a bottom-up forward pass…

Machine Learning · Computer Science 2020-10-26 Roman Pogodin , Peter E. Latham

Normative and task-driven theories offer powerful top-down explanations for biological systems, yet the goals of quantitatively arbitrating between competing theories, and utilizing them as inductive biases to improve data-driven fits of…

Artificial Intelligence · Computer Science 2025-09-30 Bahti Zakirov , Gašper Tkačik

In this study, we explore the potential of using a straightforward neural network inspired by the retina model to efficiently restore low-light images. The retina model imitates the neurophysiological principles and dynamics of various…

Computer Vision and Pattern Recognition · Computer Science 2023-05-04 Junjie Ye , Jilin Zhao

The brain learns abstract representations of high-dimensional sensory input, but the plasticity rules that enable such learning are unknown. We study biologically plausible algorithms on the Random Hierarchy Model (RHM), an artificial…

Machine Learning · Computer Science 2026-05-19 Ariane Delrocq , Wu S. Zihan , Guillaume Bellec , Wulfram Gerstner