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Bacteria are highly adaptive microorganisms that thrive in a wide range of growth conditions via changes in cell morphologies and macromolecular composition. How bacterial morphologies are regulated in diverse environmental conditions is a…

Cell Behavior · Quantitative Biology 2021-10-26 Diana Serbanescu , Nikola Ojkic , Shiladitya Banerjee

Proliferation is a defining feature of life. Through growth, division, and death, living systems consume energy and inject mass, breaking conservation laws and driving collective phenomena from biofilm formation to embryonic development.…

Statistical Mechanics · Physics 2026-03-25 Nicola Pellicciotta , Luca Angelani , Roberto Di Leonardo

Biological active materials such as bacterial biofilms and eukaryotic cells thrive in confined micro-spaces. Here, we show through numerical simulations that confinement can serve as a mechanical guidance to achieve distinct modes of…

Soft Condensed Matter · Physics 2019-08-05 Felix Kempf , Romain Mueller , Erwin Frey , Julia M. Yeomans , Amin Doostmohammadi

In systems as diverse as migrating mammals to road traffic, crowding acts to inhibit efficient collective movement. Bacteria, however, are observed to move in very dense groups containing billions of individuals without causing the gridlock…

It has recently been reported that bacteria, such as E.coli and P. putida, perform distinct modes of motion when placed in porous media as compared to dilute regions or free space. This has led us to suggest an efficient strategy for active…

Soft Condensed Matter · Physics 2022-04-12 Ehsan Irani , Zahra Mokhtari , Annette Zippelius

How systems are endowed with migration capacity is a fascinating question with implications ranging from the design of novel active systems to the control of microbial populations. Bacteria, which can be found in a variety of environments,…

Biological Physics · Physics 2017-07-03 Marc Hennes , Julien Tailleur , Gaëlle Charron , Adrian Daerr

We study the effect of discreteness on various models for patterning in bacterial colonies. In a bacterial colony with branching pattern, there are discrete entities - bacteria - which are only two orders of magnitude smaller than the…

Disordered Systems and Neural Networks · Physics 2007-05-23 Inon Cohen , Ido Golding , Yonathan Kozlovsky , Eshel Ben-Jacob

Cellular solids are known to exhibit size effects, i.e., differences in the apparent effective elastic moduli, when the specimen size becomes comparable to the cell size. The present contribution employs direct numerical simulations (DNS)…

Computational Physics · Physics 2021-01-05 Rinh Dinh Pham , Geralf Hütter

We scrutinize the temporally-resolved speed of active cargo transport in living cells, and show intermittent bursting motions. These nonlinear fluctuations follow a scaling law over several decades of time and space, the statistical…

Subcellular Processes · Quantitative Biology 2015-06-16 Bo Wang , James Kuo , Steve Granick

Directed growth, anisotropic cell shapes, and confinement drive self-organization in multicellular systems. We investigate the influence of particle shape on the distribution and dynamics of nematic microdomains in a minimal in-silico model…

Soft Condensed Matter · Physics 2025-12-03 Jonas Isensee , Philip Bittihn

Chirality, or the breaking of mirror symmetry, appears across all scales in nature, from molecular conformations to the dynamics of bacterial collectives. Environments composed of such symmetry-breaking constituents can give rise to…

Active gels are a class of biologically-relevant material containing embedded agents that spontaneously generate forces acting on a sparse filament network. In vitro experiments of protein filaments and molecular motors have revealed a…

Soft Condensed Matter · Physics 2024-06-03 David A. Head , Gerhard Gompper , W. J. Briels

Colloids coupled to a bath of swimming cells generically display enhanced diffusion. This transport dynamics stems from a subtle interplay between the active and passive particles that still resists our understanding despite decades of…

Soft Condensed Matter · Physics 2021-03-25 Antoine Lagarde , Noémie Dagès , Takahiro Nemoto , Vincent Démery , Denis Bartolo , Thomas Gibaud

In growing active matter systems, a large collection of engineered or living autonomous units metabolize free energy and create order at different length scales as they proliferate and migrate collectively. One such example is bacterial…

Soft Condensed Matter · Physics 2021-06-15 Japinder Nijjer , Changhao Li , Qiuting Zhang , Haoran Lu , Sulin Zhang , Jing Yan

Recent advances in microscopy techniques has uncovered unique aspects of flagella-driven motility in bacteria. A remarkable example is the discovery of flagellar wrapping, a phenomenon whereby a bacterium wraps its flagellum (or flagellar…

Soft Condensed Matter · Physics 2025-04-22 Takuro Kataoka , Taiju Yoneda , Daisuke Nakane , Hirofumi Wada

Biofilms in porous media critically influence hydraulic properties in environmental and engineered systems. However, a mechanistic understanding of how microbial life controls permeability remains elusive. By combining microfluidics,…

Biological Physics · Physics 2026-05-29 Wenqiao Jiao , David Scheidweiler , Nolwenn Delouche , Alberto Guadagnini , Pietro de Anna

Open cellular solids usually possess random microstructures that may contain a characteristic length scale, such as the cell size. This gives rise to size dependent mechanical properties where large systems behave differently from small…

Materials Science · Physics 2018-01-03 Stefan Liebenstein , Stefan Sandfeld , Michael Zaiser

We present a minimal continuum model of strongly adhering cells as active contractile isotropic media and use the model to study the effect of the geometry of the adhesion patch in controlling the spatial distribution of traction and…

Soft Condensed Matter · Physics 2015-06-12 Shiladitya Banerjee , M. Cristina Marchetti

We study the dynamics of micron-sized particles on a layer of motile cells. This cell carpet acts as an active bath that propels passive tracer particles via direct mechanical contact. The resulting nonequilibrium transport shows a…

Soft Condensed Matter · Physics 2024-02-27 Robert Großmann , Lara S. Bort , Ted Moldenhawer , Setareh Sharifi Panah , Ralf Metzler , Carsten Beta

Bacterial colonies are a well-known example of living active matter, exhibiting collective behaviors such as nematic alignment and collective motion that play an important role in the spread of microbial infections. While the underlying…