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Recent biological experiments have shown that certain types of cells are able to move in structured and confined environment even without the activation of focal adhesion. Focusing on this particular phenomenon and based on previous works,…

Analysis of PDEs · Mathematics 2022-12-05 Chiara Giverso , Gaspard Jankowiak , Luigi Preziosi , Christian Schmeiser

We propose a new type of traveling wave pattern, one that can adapt to the size of physical system in which it is embedded. Such a system arises when the initial state has an instability that extends down to zero wavevector, connecting at…

Subcellular Processes · Quantitative Biology 2017-01-04 David A. Kessler , Herbert Levine

We investigate active particles that exhibit long-range interactions only restricted by a field of view, which is characterized by an angle $\beta$. We show that constraining attractive interactions to a field of view leads to the emergence…

Biological Physics · Physics 2026-04-03 Edgardo Brigatti , Fernando Peruani

Order and alignment are ubiquitous in growing colonies of rod-shaped bacteria due to the nematic properties of the constituent particles. These effects are the result of the active stresses generated by growth, passive mechanical…

Soft Condensed Matter · Physics 2022-07-07 Jonas Isensee , Lukas Hupe , Ramin Golestanian , Philip Bittihn

Transport properties of particles in confining geometries show very specific characteristics as lateral drift, oscillatory movement between lateral walls or the deformation of flexible fibers. These dynamics result from viscous friction…

Fluid Dynamics · Physics 2020-04-03 M. Bechert , J. Cappello , M. Daïeff , F. Gallaire , A. Lindner , C. Duprat

Anomalous diffusion or, more generally, anomalous transport, with nonlinear dependence of the mean-squared displacement on the measurement time, is ubiquitous in nature. It has been observed in processes ranging from microscopic movement of…

Understanding how bacteria move in porous media is critical to applications in healthcare, agriculture, environmental remediation, and chemical sensing. Recent work has demonstrated that E. coli, which moves by run-and-tumble dynamics in a…

Soft Condensed Matter · Physics 2022-06-07 Tapomoy Bhattacharjee , Sujit S. Datta

Natural habitats of most living microorganisms are distinguished by a complex structure often formed by a porous medium such as soil. The dynamics and transport properties of motile microorganisms are strongly affected by crowded and…

Soft Condensed Matter · Physics 2023-06-23 Florian von Rüling , Liubov Bakhchova , Ulrike Steinmann , Alexey Eremin

Biological systems are majorly dependent on their property of bistability in order to exhibit nongenetic heterogeneity in terms of cellular morphology and physiology. Spatial patterns of phenotypically heterogeneous cells, arising due to…

Quantitative Methods · Quantitative Biology 2023-01-25 Priya Chakraborty , Ushasi Roy , Mohit K. Jolly , Sayantari Ghosh

In densely-packed two-dimensional systems of growing cells, such as rod-shaped bacteria, a number of experimental and numerical studies report distinct patterns of nematic orientational order in the presence of confinement. So far, these…

Soft Condensed Matter · Physics 2025-06-13 Lukas Hupe , Jonas Isensee , Ramin Golestanian , Philip Bittihn

We study colonies of non-motile, rod-shaped bacteria growing on solid substrates. In our model, bacteria interact purely mechanically, by pushing each other away as they grow, and consume a diffusing nutrient. We show that mechanical…

Biological Physics · Physics 2015-06-15 F. D. C. Farrell , O. Hallatschek , D. Marenduzzo , B. Waclaw

The study of the interactions of living adherent cells with mechanically stable (visco)elastic materials enables understanding and exploiting physiological phenomena mediated by cell-extracellular communication. However, insight on the…

Recent experiments have illuminated a remarkable growth mechanism of rod-shaped bacteria: proteins associated with cell wall extension move at constant velocity in circles oriented approximately along the cell circumference (Garner et al.,…

Biological Physics · Physics 2013-05-15 Ariel Amir , David R. Nelson

Motor-proteins are responsible for transport inside cells. Harnessing their activity is key towards developing new nano-technologies, or functional biomaterials. Cytoskeleton-like networks, recently tailored in vitro, result from the…

Soft Condensed Matter · Physics 2016-06-21 Pau Guillamat , Jordi Ignés-Mullol , Francesc Sagués

Eukaryotic cells and intracellular pathogens such as bacteria or viruses utilize the actin polymerization machinery to propel themselves forward. Thereby, the onset of motion and choice of direction may be the result of a spontaneous…

Soft Condensed Matter · Physics 2009-09-04 Karin John , Denis Caillerie , Philippe Peyla , Mourad Ismail , Annie Raoult , Jacques Prost

Randomly moving active particles can be herded into directed motion by asymmetric geometric structures. Although such a rectification process has been extensively studied due to its fundamental, biological, and technological relevance, a…

Soft Condensed Matter · Physics 2026-03-31 Satyam Anand , Xiaolei Ma , Shuo Guo , Stefano Martiniani , Xiang Cheng

Applying mechanical perturbations in a granular assembly may rearrange the configuration of the particles. However, the spatial propagation of an event is not related to the size of the external perturbation alone. Thus, the characteristic…

Fluid Dynamics · Physics 2018-05-24 Aymeric Merceron , Alban Sauret , Pierre Jop

We investigate the transport of interacting active run-and-tumble particles moving under an external drift force through a periodic array of obstacles for increasing drive amplitudes. For high activity where the system forms a motility…

Soft Condensed Matter · Physics 2024-04-23 C. Reichhardt , C. J. O. Reichhardt

Transport across heterogeneous, patchy environments is a ubiquitous phenomenon spanning fields of study including ecological movement, intracellular transport and regions of specialised function in a cell. These regions or patches may be…

Statistical Mechanics · Physics 2017-10-06 Sergei Fedotov , Helena Stage

The striking variety of macroscopic morphologies displayed by bacterial colonies depends on microscopic environmental and behavioural details in a manner that is currently not well understood. A surprising example is sibling inhibition,…

Cell Behavior · Quantitative Biology 2026-05-15 Dario Buonomo , Francesco Imperi , Fabio Bruni , Marco Polin , Barbara Capone