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The aetiology of polygenic obesity is multifactorial, which indicates that life-style and environmental factors may influence multiples genes to aggravate this disorder. Several low-risk single nucleotide polymorphisms (SNPs) have been…

Genomics · Quantitative Biology 2018-08-27 Casimiro A. Curbelo Montañez , Paul Fergus , Carl Chalmers , Jade Hind

A natural way of handling imbalanced data is to attempt to equalise the class frequencies and train the classifier of choice on balanced data. For two-class imbalanced problems, the classification success is typically measured by the…

Computer Vision and Pattern Recognition · Computer Science 2018-04-20 Ludmila I. Kuncheva , Álvar Arnaiz-González , José-Francisco Díez-Pastor , Iain A. D. Gunn

When searching for gene pathways leading to specific disease outcomes, additional information on gene characteristics is often available that may facilitate to differentiate genes related to the disease from irrelevant background when…

Machine Learning · Statistics 2018-09-10 Yunpeng Zhao , Qing Pan , Chengan Du

The World Health Organization (WHO) reported 1.25 million deaths yearly due to road traffic accidents worldwide and the number has been continuously increasing over the last few years. Nearly fifth of these accidents are caused by…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Hesham M. Eraqi , Yehya Abouelnaga , Mohamed H. Saad , Mohamed N. Moustafa

Genome-wide association studies (GWAS) have successfully identified over two hundred thousand genotype-trait associations. Yet some challenges remain. First, complex traits are often associated with many single nucleotide polymorphisms…

Methodology · Statistics 2023-02-07 Aastha Khatiwada , Ayse Selen Yilmaz , Bethany J. Wolf , Maciej Pietrzak , Dongjun Chung

Optimizing molecular properties while preserving biological activity is a central challenge in drug design. Bioisosteric replacement, which substitutes a molecular fragment with a chemically or biologically analogous moiety, offers a…

Biomolecules · Quantitative Biology 2025-12-04 Hyeongwoo Kim , Seokhyun Moon , Wonho Zhung , Shinwoo Kim , Jaechang Lim , Woo Youn Kim

In the context of network data, bipartite networks are of particular interest, as they provide a useful description of systems representing relationships between sending and receiving nodes. In this framework, we extend the Mixture of…

Methodology · Statistics 2024-04-16 Dalila Failli , Maria Francesca Marino , Francesca Martella

Selectivity estimation - the problem of estimating the result size of queries - is a fundamental problem in databases. Accurate estimation of query selectivity involving multiple correlated attributes is especially challenging. Poor…

Databases · Computer Science 2019-06-19 Shohedul Hasan , Saravanan Thirumuruganathan , Jees Augustine , Nick Koudas , Gautam Das

This paper explores object detection in the small data regime, where only a limited number of annotated bounding boxes are available due to data rarity and annotation expense. This is a common challenge today with machine learning being…

Computer Vision and Pattern Recognition · Computer Science 2019-10-17 Lanlan Liu , Michael Muelly , Jia Deng , Tomas Pfister , Li-Jia Li

Heart disease remains a leading cause of mortality and morbidity worldwide, necessitating the development of accurate and reliable predictive models to facilitate early detection and intervention. While state of the art work has focused on…

Machine Learning · Computer Science 2025-05-23 Mahade Hasan , Farhana Yasmin , Xue Yu

We propose and develop a Bayesian plaid model for biclustering that accounts for the prior dependency between genes (and/or conditions) through a stochastic relational graph. This work is motivated by the need for improved understanding of…

Applications · Statistics 2015-11-18 Thierry Chekouo , Alejandro Murua , Wolfgang Raffelsberger

Fine-grained object recognition concerns the identification of the type of an object among a large number of closely related sub-categories. Multisource data analysis, that aims to leverage the complementary spectral, spatial, and…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Gencer Sumbul , Ramazan Gokberk Cinbis , Selim Aksoy

Integrative learning of multiple datasets has the potential to mitigate the challenge of small $n$ and large $p$ that is often encountered in analysis of big biomedical data such as genomics data. Detection of weak yet important signals can…

Methodology · Statistics 2022-07-04 Changgee Chang , Zongyu Dai , Jihwan Oh , Qi Long

Multi-view datasets offer diverse forms of data that can enhance prediction models by providing complementary information. However, the use of multi-view data leads to an increase in high-dimensional data, which poses significant challenges…

Neural and Evolutionary Computing · Computer Science 2024-03-05 Vandad Imani , Carlos Sevilla-Salcedo , Elaheh Moradi , Vittorio Fortino , Jussi Tohka

Deep learning has significantly advanced building segmentation in remote sensing, yet models struggle to generalize on data of diverse geographic regions due to variations in city layouts and the distribution of building types, sizes and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Shuang Song , Yang Tang , Rongjun Qin

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

Automatic instance segmentation is a problem that occurs in many biomedical applications. State-of-the-art approaches either perform semantic segmentation or refine object bounding boxes obtained from detection methods. Both suffer from…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Long Chen , Martin Strauch , Dorit Merhof

Bi-clustering is a useful approach in analyzing biological data when observations come from heterogeneous groups and have a large number of features. We outline a general Bayesian approach in tackling bi-clustering problems in moderate to…

Applications · Statistics 2021-02-11 Han Yan , Jiexing Wu , Yang Li , Jun S. Liu

A central problem in machine learning and pattern recognition is the process of recognizing the most important features. In this paper, we provide a new feature selection method (DRPT) that consists of first removing the irrelevant features…

Machine Learning · Computer Science 2021-05-19 Majid Afshar , Hamid Usefi

2 Diabetes is a leading worldwide public health concern, and its increasing prevalence has significant health and economic importance in all nations. The condition is a multifactorial disorder with a complex aetiology. The genetic…

Machine Learning · Computer Science 2018-08-30 Basma Abdulaimma , Paul Fergus , Carl Chalmers
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