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Identifying phenotypes plays an important role in furthering our understanding of disease biology through practical applications within healthcare and the life sciences. The challenge of dealing with the complexities and noise within…

Applications · Statistics 2023-04-28 Andre Vauvelle , Hamish Tomlinson , Aaron Sim , Spiros Denaxas

This study proposes a data condensation method for multivariate kernel density estimation by genetic algorithm. First, our proposed algorithm generates multiple subsamples of a given size with replacement from the original sample. The…

Methodology · Statistics 2022-03-04 Kiheiji Nishida

ICU mortality scoring systems attempt to predict patient mortality using predictive models with various clinical predictors. Examples of such systems are APACHE, SAPS and MPM. However, most such scoring systems do not actively look for and…

Neural and Evolutionary Computing · Computer Science 2016-04-25 Chee Chun Gan , Gerard Learmonth

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from existing approaches are not necessarily…

Quantitative Methods · Quantitative Biology 2022-03-01 Lingsong Meng , Dorina Avram , George Tseng , Zhiguang Huo

We consider a problem of data integration. Consider determining which genes affect a disease. The genes, which we call predictor objects, can be measured in different experiments on the same individual. We address the question of finding…

Machine Learning · Statistics 2016-10-04 Xin Gao , Raymond J. Carroll

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from conventional approaches may not be…

Applications · Statistics 2023-09-28 Lingsong Meng , Zhiguang Huo

Decision trees are a popular family of models due to their attractive properties such as interpretability and ability to handle heterogeneous data. Concurrently, missing data is a prevalent occurrence that hinders performance of machine…

Machine Learning · Computer Science 2020-07-01 Pasha Khosravi , Antonio Vergari , YooJung Choi , Yitao Liang , Guy Van den Broeck

The advent of next-generation sequencing-based spatially resolved transcriptomics (SRT) techniques has reshaped genomic studies by enabling high-throughput gene expression profiling while preserving spatial and morphological context.…

Applications · Statistics 2025-02-20 Bencong Zhu , Alberto Cassese , Marina Vannucci , Michele Guindani , Qiwei Li

In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…

Methodology · Statistics 2019-03-27 Naim U. Rashid , Quefeng Li , Jen Jen Yeh , Joseph G. Ibrahim

Bi-clustering is a technique that allows for the simultaneous clustering of observations and features in a dataset. This technique is often used in bioinformatics, text mining, and time series analysis. An important advantage of…

Computation · Statistics 2023-02-09 Anastasiia Livochka , Ryan Browne , Sanjeena Subedi

With the rapid development of online social media, online shopping sites and cyber-physical systems, heterogeneous information networks have become increasingly popular and content-rich over time. In many cases, such networks contain…

Databases · Computer Science 2012-02-01 Yizhou Sun , Charu C. Aggarwal , Jiawei Han

Biclustering is a powerful approach to search for patterns in data, as it can be driven by a function that measures the quality of diverse types of patterns of interest. However, due to its computational complexity, the exploration of the…

Machine Learning · Computer Science 2021-04-27 Marcin Michalak , Jesús S. Aguilar-Ruiz

In this paper a novel biclustering algorithm based on artificial intelligence (AI) is introduced. The method called EBIC aims to detect biologically meaningful, order-preserving patterns in complex data. The proposed algorithm is probably…

Machine Learning · Computer Science 2018-07-27 Patryk Orzechowski , Moshe Sipper , Xiuzhen Huang , Jason H. Moore

High false alarm rate in intensive care units (ICUs) has been identified as one of the most critical medical challenges in recent years. This often results in overwhelming the clinical staff by numerous false or unurgent alarms and…

Signal Processing · Electrical Eng. & Systems 2018-05-01 Mohammad Zaeri-Amirani , Fatemeh Afghah , Sajad Mousavi

Healthcare datasets often contain groups of highly correlated features, such as features from the same biological system. When feature selection is applied to these datasets to identify the most important features, the biases inherent in…

Machine Learning · Computer Science 2022-07-07 Annette Spooner , Gelareh Mohammadi , Perminder S. Sachdev , Henry Brodaty , Arcot Sowmya

Classification in the dissimilarity space has become a very active research area since it provides a possibility to learn from data given in the form of pairwise non-metric dissimilarities, which otherwise would be difficult to cope with.…

We consider the problem of retrieving objects from image data and learning to classify them into meaningful semantic categories with minimal supervision. To that end, we propose a fully differentiable unsupervised deep clustering approach…

Computer Vision and Pattern Recognition · Computer Science 2018-07-25 Steven Hickson , Anelia Angelova , Irfan Essa , Rahul Sukthankar

Biclustering numerical data became a popular data-mining task in the beginning of 2000's, especially for analysing gene expression data. A bicluster reflects a strong association between a subset of objects and a subset of attributes in a…

Data Structures and Algorithms · Computer Science 2011-11-15 Mehdi Kaytoue , Sergei O. Kuznetsov , Juraj Macko , Wagner Meira , Amedeo Napoli

Data-driven approaches have become a dominant paradigm for robotic grasp planning. However, the performance of these approaches is enormously influenced by the quality of the available training data. In this paper, we propose a framework to…

Robotics · Computer Science 2022-09-07 Junnan Jiang , Yuyang Tu , Xiaohui Xiao , Zhongtao Fu , Jianwei Zhang , Fei Chen , Miao Li

Disentangled distributed representations of data are desirable for machine learning, since they are more expressive and can generalize from fewer examples. However, for complex data, the distributed representations of multiple objects…

Machine Learning · Computer Science 2016-01-21 Klaus Greff , Rupesh Kumar Srivastava , Jürgen Schmidhuber