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Numerous Knowledge Graphs (KGs) are being created to make Recommender Systems (RSs) not only intelligent but also knowledgeable. Integrating a KG in the recommendation process allows the underlying model to extract reasoning paths between…

Information Retrieval · Computer Science 2022-11-11 Giacomo Balloccu , Ludovico Boratto , Gianni Fenu , Mirko Marras

Knowledge graphs (KGs) are powerful tools for modelling complex, multi-relational data and supporting hypothesis generation, particularly in applications like drug repurposing. However, for predictive methods to gain acceptance as credible…

Artificial Intelligence · Computer Science 2026-02-06 Susana Nunes , Samy Badreddine , Catia Pesquita

The effective analysis of high-dimensional Electronic Health Record (EHR) data, with substantial potential for healthcare research, presents notable methodological challenges. Employing predictive modeling guided by a knowledge graph (KG),…

Methodology · Statistics 2025-11-06 Zhiwei Xu , Ziming Gan , Doudou Zhou , Shuting Shen , Junwei Lu , Tianxi Cai

Disease progression models are instrumental in predicting individual-level health trajectories and understanding disease dynamics. Existing models are capable of providing either accurate predictions of patients prognoses or clinically…

Machine Learning · Computer Science 2018-10-25 Ahmed M. Alaa , Mihaela van der Schaar

In response to the COVID-19 pandemic, the integration of interpretable machine learning techniques has garnered significant attention, offering transparent and understandable insights crucial for informed clinical decision making. This…

Machine Learning · Computer Science 2024-09-10 Jinzhi Shen , Ke Ma

We intend to create a new risk assessment methodology that combines the best characteristics of both risk score and machine learning models. More specifically, we aim to develop a method that, besides having a good performance, offers a…

Machine Learning · Computer Science 2021-10-19 Francisco Valente , Jorge Henriques , Simão Paredes , Teresa Rocha , Paulo de Carvalho , João Morais

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

Machine Learning · Computer Science 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

The deployment of reinforcement learning (RL) in the real world comes with challenges in calibrating user trust and expectations. As a step toward developing RL systems that are able to communicate their competencies, we present a method of…

Machine Learning · Computer Science 2020-11-19 Aastha Acharya , Rebecca Russell , Nisar R. Ahmed

In this paper, we consider the problem of disease diagnosis. Unlike the conventional learning paradigm that treats labels independently, we propose a knowledge-enhanced framework, that enables training visual representation with the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 Chaoyi Wu , Xiaoman Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

Accurate and interpretable prediction of estimated glomerular filtration rate (eGFR) is essential for managing chronic kidney disease (CKD) and supporting clinical decisions. Recent advances in Large Multimodal Models (LMMs) have shown…

Machine Learning · Computer Science 2025-07-31 Peng-Yi Wu , Pei-Cing Huang , Ting-Yu Chen , Chantung Ku , Ming-Yen Lin , Yihuang Kang

This study addresses a critical gap in the healthcare system by developing a clinically meaningful, practical, and explainable disease surveillance system for multiple chronic diseases, utilizing routine EHR data from multiple U.S.…

Machine Learning · Computer Science 2025-01-28 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Ahmad Abdullah , Ibrahim Hashmat , Muddassar Farooq

In healthcare there is a pursuit for employing interpretable algorithms to assist healthcare professionals in several decision scenarios. Following the Predictive, Descriptive and Relevant (PDR) framework, the definition of interpretable…

Understanding how small molecules perturb gene expression is essential for uncovering drug mechanisms, predicting off-target effects, and identifying repurposing opportunities. While prior deep learning frameworks have integrated multimodal…

Machine Learning · Computer Science 2026-01-01 Pascal Passigan , Kevin Zhu , Angelina Ning

Objective: Electronic medical records (EMRs) contain an amount of medical knowledge which can be used for clinical decision support (CDS). Our objective is a general system that can extract and represent these knowledge contained in EMRs to…

Artificial Intelligence · Computer Science 2017-09-21 Chao Zhao , Jingchi Jiang , Yi Guan

Knowledge graph completion (a.k.a.~link prediction), i.e.,~the task of inferring missing information from knowledge graphs, is a widely used task in many applications, such as product recommendation and question answering. The…

Artificial Intelligence · Computer Science 2022-07-05 Zoi Kaoudi , Abelardo Carlos Martinez Lorenzo , Volker Markl

Predicting the health risks of patients using Electronic Health Records (EHR) has attracted considerable attention in recent years, especially with the development of deep learning techniques. Health risk refers to the probability of the…

Machine Learning · Computer Science 2022-11-15 Yuxi Liu , Shaowen Qin , Antonio Jimeno Yepes , Wei Shao , Zhenhao Zhang , Flora D. Salim

Interpretability has become an essential topic for artificial intelligence in some high-risk domains such as healthcare, bank and security. For commonly-used tabular data, traditional methods trained end-to-end machine learning models with…

Artificial Intelligence · Computer Science 2022-08-18 Haixiao Chi , Dawei Wang , Gaojie Cui , Feng Mao , Beishui Liao

Despite the growing use of Electronic Health Records (EHR) for AI-assisted diagnosis prediction, most data-driven models struggle to incorporate clinically meaningful medical knowledge. They often rely on limited ontologies, lacking…

Machine Learning · Computer Science 2025-04-17 Pengfei Hu , Chang Lu , Fei Wang , Yue Ning

The lack of interpretability and transparency are preventing economists from using advanced tools like neural networks in their empirical research. In this paper, we propose a class of interpretable neural network models that can achieve…

Econometrics · Economics 2020-12-01 Yucheng Yang , Zhong Zheng , Weinan E

Predictive modelling is important for health data analysis and data-driven clinical decision-making. However, predictive studies are challenging to design optimally by hand when tens or even hundreds of features require selection,…