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Positron emission tomography (PET) suffers from severe resolution limitations which limit its quantitative accuracy. In this paper, we present a super-resolution (SR) imaging technique for PET based on convolutional neural networks (CNNs).…

Model based iterative reconstruction (MBIR) algorithms for low-dose X-ray CT are computationally expensive. To address this problem, we recently proposed a deep convolutional neural network (CNN) for low-dose X-ray CT and won the second…

Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

Accurate medical image segmentation allows for the precise delineation of anatomical structures and pathological regions, which is essential for treatment planning, surgical navigation, and disease monitoring. Both CNN-based and…

Deep-learning-based MR-to-CT synthesis can estimate the electron density of tissues, thereby facilitating PET attenuation correction in whole-body PET/MR imaging. However, whole-body MR-to-CT synthesis faces several challenges including the…

Automated lesion segmentation from computed tomography (CT) is an important and challenging task in medical image analysis. While many advancements have been made, there is room for continued improvements. One hurdle is that CT images can…

Image restoration and spectral reconstruction are longstanding computer vision tasks. Currently, CNN-transformer hybrid models provide state-of-the-art performance for these tasks. The key common ingredient in the architectural designs of…

Magnetic resonance imaging (MRI) is a non-invasive medical imaging technique offering high-resolution 3D images and valuable insights into human tissue conditions. Even at present, the refinement of denoising methods for MRI remains a…

Low-dose computed tomography (LDCT) reduces radiation exposure but often degrades image quality, potentially compromising diagnostic accuracy. Existing deep learning-based denoising methods focus primarily on pixel-level mappings,…

Inspired by complexity and diversity of biological neurons, our group proposed quadratic neurons by replacing the inner product in current artificial neurons with a quadratic operation on input data, thereby enhancing the capability of an…

Deep convolutional neural networks (DCNN) have demonstrated its capability to convert MR image to pseudo CT for PET attenuation correction in PET/MRI. Conventionally, attenuated events are corrected in sinogram space using attenuation maps…

While Computerized Tomography (CT) images can help detect disease such as Covid-19, regular CT machines are large and expensive. Cheaper and more portable machines suffer from errors in geometry acquisition that downgrades CT image quality.…

Deep learning has been successfully applied to low-dose CT (LDCT) image denoising for reducing potential radiation risk. However, the widely reported supervised LDCT denoising networks require a training set of paired images, which is…

The convolutional neural network (CNN) is one of the most commonly used architectures for computer vision tasks. The key building block of a CNN is the convolutional kernel that aggregates information from the pixel neighborhood and shares…

In the intention of minimizing excessive X-ray radiation administration to patients, low-dose computed tomography (LDCT) has become a distinct trend in radiology. However, while lowering the radiation dose reduces the risk to the patient,…

With the development of computed tomography (CT) imaging technology, it is possible to acquire multi-energy data by spectral CT. Being different from conventional CT, the X-ray energy spectrum of spectral CT is cutting into several narrow…

Here we present new joint reconstruction and regularization techniques inspired by ideas in microlocal analysis and lambda tomography, for the simultaneous reconstruction of the attenuation coefficient and electron density from X-ray…

Positron range (PR) limits spatial resolution and quantitative accuracy in PET imaging, particularly for high-energy positron-emitting radionuclides like 68Ga. We propose a deep learning method using 3D residual encoder-decoder…

Neural cellular automata represent an evolution of the traditional cellular automata model, enhanced by the integration of a deep learning-based transition function. This shift from a manual to a data-driven approach significantly increases…

The integrated positron emission tomography/magnetic resonance imaging (PET/MRI) scanner facilitates the simultaneous acquisition of metabolic information via PET and morphological information with high soft-tissue contrast using MRI.…