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Optical coherence tomography (OCT) is a noninvasive technology that enables real-time imaging of tissue microanatomies. The axial resolution of OCT is intrinsically constrained by the spectral bandwidth of the employed light source while…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Kaiyan Li , Jingyuan Yang , Wenxuan Liang , Xingde Li , Chenxi Zhang , Lulu Chen , Chan Wu , Xiao Zhang , Zhiyan Xu , Yuelin Wang , Lihui Meng , Yue Zhang , Youxin Chen , S. Kevin Zhou

Optical Coherence Tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though OCT offers high…

Medical Physics · Physics 2020-05-29 Cerine Lal , Sergey Alexandrov , Sweta Rani , Yi Zhou , Thomas Ritter , Martin Leahy

Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and…

Medical Physics · Physics 2019-07-02 Cerine Lal , Hrebesh M Subhash , Sergey Alexandrov , Martin J Leahy

High-contrast imaging relies on advanced coronagraphs and adaptive optics (AO) to attenuate the starlight. However, residual aberrations, especially non-common path aberrations between the AO channel and the coronagraph channel, limit the…

Instrumentation and Methods for Astrophysics · Physics 2025-11-11 Axel Potier , Raphaël Galicher , Pierre Baudoz , Johan Mazoyer , Zahed Wahhaj , Ruben Tandon , Jonas G. Kühn , Laura Perez , Gael Chauvin

Coherent diffraction imaging (CDI) is high-resolution lensless microscopy that has been applied to image a wide range of specimens using synchrotron radiation, X-ray free electron lasers, high harmonic generation, soft X-ray laser and…

Optics · Physics 2014-01-23 Jose A Rodriguez , Rui Xu , Chien-Chun Chen , Yunfei Zou , Jianwei Miao

Spectral domain optical coherence tomography (OCT) offers high resolution multidimensional imaging, but generally suffers from defocussing, intensity falloff and shot noise, causing artifacts and image degradation along the imaging depth.…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Jonathan H. Mason , Yvonne Reinwald , Ying Yang , Sarah Waters , Alicia El Haj , Pierre O. Bagnaninchi

A major limitation of transient optical spectroscopy is that relatively high laser fluences are required to enable broadband, multichannel detection with acceptable signal-to-noise levels. Under typical experimental conditions, many…

Optics · Physics 2023-05-03 Siedah J. Hall , Peter J. Budden , Anne Zats , Matthew Y. Sfeir

In numerous applications, Fourier-domain optical coherence tomography (FD-OCT) suffers from a limited imaging depth due to signal roll-off, a limited focal range, and autocorrelation noise. Here, we propose a parallel full-field FD-OCT…

The ultimate sensitivity of optical measurements is a key element of many recent works. Classically, it is mainly limited by the shot noise limit. However, a measurement setup that incorporates quantum mechanical principles can surpass the…

Quantum Physics · Physics 2013-11-13 L. Cohen , D. Istrati , L. Dovrat , H. S. Eisenberg

With the introduction of spectral-domain optical coherence tomography (OCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, the need for 3-D…

Computer Vision and Pattern Recognition · Computer Science 2012-05-03 Yankui Sun , Tian Zhang

Optical coherence tomography (OCT) is a micrometer-scale, volumetric imaging modality that has become a clinical standard in ophthalmology. OCT instruments image by raster-scanning a focused light spot across the retina, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2022-09-16 Stefan Ploner , Siyu Chen , Jungeun Won , Lennart Husvogt , Katharina Breininger , Julia Schottenhamml , James Fujimoto , Andreas Maier

Optical coherence tomography (OCT) has seen widespread success as an in vivo clinical diagnostic 3D imaging modality, impacting areas including ophthalmology, cardiology, and gastroenterology. Despite its many advantages, such as high…

In ultra-high resolution (UHR-) optical coherence tomography (OCT) group velocity dispersion (GVD) must be corrected for in order to approach the theoretical resolution limit. One approach promises not only compensation, but complete…

Optical Coherence Tomography (OCT) is an emerging technique in the field of biomedical imaging, with applications in ophthalmology, dermatology, coronary imaging etc. Due to the underlying physics, OCT images usually suffer from a granular…

Computer Vision and Pattern Recognition · Computer Science 2015-02-10 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning-based image reconstruction framework that can generate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-30 Yijie Zhang , Tairan Liu , Manmohan Singh , Yilin Luo , Yair Rivenson , Kirill V. Larin , Aydogan Ozcan

The choroid is a key vascular layer of the eye, supplying oxygen to the retinal photoreceptors. Non-invasive enhanced depth imaging optical coherence tomography (EDI-OCT) has recently improved access and visualisation of the choroid, making…

The development of practical sensors for optical coherence tomography (OCT) with undetected photons requires miniaturization via integration. To be practical, these sensors must exhibit a large spectral bandwidth and a high brightness,…

In conventional OCT, broadband light sources are generally utilized to obtain high axial resolution due to their low temporal coherence (TC) length. Purely monochromatic (i.e., high TC length) light sources like laser cannot be implemented…

Deploying Vision Transformers (ViTs) on near-sensor analog accelerators demands training pipelines that are explicitly aligned with device-level noise and energy constraints. We introduce a compact framework for silicon-photonic execution…

Emerging Technologies · Computer Science 2026-04-07 Xuming Chen , Deniz Najafi , Chengwei Zhou , Pietro Mercati , Arman Roohi , Mohsen Imani , Mahdi Nikdast , Shaahin Angizi , Gourav Datta

Computed Tomography (CT) imposes risk on the patients due to its inherent X-ray radiation, stimulating the development of low-dose CT (LDCT) imaging methods. Lowering the radiation dose reduces the health risks but leads to noisier…

Image and Video Processing · Electrical Eng. & Systems 2022-11-03 Elvira Zainulina , Alexey Chernyavskiy , Dmitry V. Dylov