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Optical diffraction tomography (ODT) is a three-dimensional (3D) quantitative phase imaging technique, which enables the reconstruction of the 3D refractive index (RI) distribution of a transparent sample. Due to its fast, non-invasive, and…

Optics · Physics 2018-11-14 Chansuk Park , Seungwoo Shin , Yongkeun Park

Optical coherence tomography (OCT) has revolutionized retinal disease diagnosis with its high-resolution and three-dimensional imaging nature, yet its full diagnostic automation in clinical practices remains constrained by multi-stage…

Optical Coherence Tomography (OCT) provides a unique ability to image the eye retina in 3D at micrometer resolution and gives ophthalmologist the ability to visualize retinal diseases such as Age-Related Macular Degeneration (AMD). While…

Computer Vision and Pattern Recognition · Computer Science 2016-10-13 Stefanos Apostolopoulos , Carlos Ciller , Sandro I. De Zanet , Sebastian Wolf , Raphael Sznitman

Demand for low-noise, continuous-wave, frequency-tunable lasers based on semiconductor integrated photonics has been advancing in support of numerous applications. In particular, an important goal is to achieve narrow spectral linewidth,…

We design a system-level architecture for approaching the shot noise limit for passive triangulation of a quasi-monochromatic point source. Our emphasis is not in the novelty of the basic physics, but that existing systems lose fundamental…

Optics · Physics 2026-05-07 John C. Howell , Andrew N. Jordan

We present an ultrahigh-$Q$, solid-silica microrod resonator operated under ambient conditions that supports laser-fractional-frequency stabilization to the thermal-noise limit of $3 \times 10^{-13}$ and a linewidth of 62 Hz. We…

Instrumentation and Detectors · Physics 2019-08-14 Wei Zhang , Fred Baynes , Scott A. Diddams , Scott B. Papp

Improving the spatial resolution of CT images is a meaningful yet challenging task, often accompanied by the issue of noise amplification. This article introduces an innovative framework for noise-controlled CT super-resolution utilizing…

Computer Vision and Pattern Recognition · Computer Science 2025-02-17 Yuang Wang , Siyeop Yoon , Rui Hu , Baihui Yu , Duhgoon Lee , Rajiv Gupta , Li Zhang , Zhiqiang Chen , Dufan Wu

Quantum Optical Coherence Tomography (Q-OCT) is the non-classical counterpart of Optical Coherence Tomography (OCT) - a high-resolution 3D imaging technique based on white-light interferometry. Because Q-OCT uses a source of…

The future interconnect links in intra- and inter-chip require the photodetector with high bandwidth, ultra-wide waveband, compact footprint, low-cost, and compatible integration process with silicon complementary metal-oxide-semiconductor…

Optics · Physics 2023-03-16 Weifeng Wu , Fan Yang , Xiansong Fang , Xiang Cai , Xiaohui Liu , Fan Zhang , Sheng Wang

Chromatic dispersion is a common problem to degrade the system resolution in optical coherence tomography (OCT). This study is to develop a deep learning network for automated dispersion compensation (ADC-Net) in OCT. The ADC-Net is based…

Coherence properties and wavelength of light sources are indispensable for optical coherence microscopy/tomography as they greatly influence the signal to noise ratio, axial resolution, and penetration depth of the system. In the present…

Many biological and soft matter processes occur at high speeds in complex 3D environments, and developing imaging techniques capable of elucidating their dynamics is an outstanding experimental challenge. Here, we introduce Fourier…

Optical coherence tomography (OCT) is an important interferometric diagnostic technique which provides cross-sectional views of the subsurface microstructure of biological tissues. However, the imaging quality of high-speed OCT is limited…

Computer Vision and Pattern Recognition · Computer Science 2015-03-13 Liheng Bian , Jinli Suo , Feng Chen , Qionghai Dai

We present a finite difference time domain (FDTD) model for computation of A line scans in time domain optical coherence tomography (OCT). By simulating only the end of the two arms of the interferometer and computing the interference…

Medical Physics · Physics 2018-07-12 F. Troiani , K. Nikolic , T. G. Constandinou

Optical coherence tomography (OCT) is pivotal in corneal imaging for both surgical planning and diagnosis. However, high-speed acquisitions often degrade spatial resolution and increase speckle noise, posing challenges for accurate…

Image and Video Processing · Electrical Eng. & Systems 2026-02-04 Yaning Wang , Jinglun Yu , Wenhan Guo , Ziyi Huang , Rosalinda Xiong , Yu Sun , Jin U. Kang

We apply three optical coherence tomography (OCT) image analysis techniques to extract morphometric information from OCT images obtained on peripheral nerves of rat. The accuracy of each technique is evaluated against histological…

Tissues and Organs · Quantitative Biology 2019-01-09 J. Hope , B. Brauer , S. Amirapu , A. McDaid , F. Vanholsbeeck

Background: Cervical cancer seriously affects the health of the female reproductive system. Optical coherence tomography (OCT) emerged as a non-invasive, high-resolution imaging technology for cervical disease detection. However, OCT image…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Kaiyi Chen , Qingbin Wang , Yutao Ma

Optical diffraction tomography (ODT) enables non-invasive information-rich 3D refractive index (RI) reconstruction of unimpaired transparent biological and technical samples, crucial in biomedical research, optical metrology, materials…

Based on high-throughput dark-field full-field optical coherence tomography, we designed and built an OCT system that can measure a variety of samples with different scattered light intensities, such as materials with multi-layer…

Optics · Physics 2024-01-30 Youlong Fan , Qingye Hu , Zhongping Wang , Xiantao Wei , Zengming Zhang

The emerging technique of mid-infrared optical coherence tomography (MIR-OCT) takes advantage of the reduced scattering of MIR light in various materials and devices, enabling tomographic imaging at deeper penetration depths. Because of…

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