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Non-human primates (NHPs) serve as critical models for understanding human brain function and neurological disorders due to their close evolutionary relationship with humans. Accurate brain tissue segmentation in NHPs is critical for…

Multi-modal neuroimaging projects are advancing our understanding of human brain architecture, function, connectivity using high-quality non-invasive data from many subjects. However, ground truth validation of connectivity using invasive…

Magnetic resonance imaging (MRI) has greatly advanced neuroscience research and clinical diagnostics. However, imaging data collected across different scanners, acquisition protocols, or imaging sites often exhibit substantial…

Image and Video Processing · Electrical Eng. & Systems 2026-04-02 Qinqin Yang , Firoozeh Shomal-Zadeh , Ali Gholipour

Lack of standardization and various intrinsic parameters for magnetic resonance (MR) image acquisition results in heterogeneous images across different sites and devices, which adversely affects the generalization of deep neural networks.…

Data standardization has become one of the leading methods neuroimaging researchers rely on for data sharing and reproducibility. Data standardization promotes a common framework through which researchers can utilize others' data. Yet, as…

Head magnetic resonance imaging (MRI) data are routinely collected and shared for research under strict regulatory frameworks that require the removal of direct identifiers prior to data release. However, even after skull stripping, brain…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Gaurang Sharma , Harri Polonen , Juha Pajula , Jutta Suksi , Jussi Tohka

This paper presents an annotated dataset of brain MRI images designed to advance the field of brain symmetry study. Magnetic resonance imaging (MRI) has gained interest in analyzing brain symmetry in neonatal infants, and challenges remain…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Arnaud Gucciardi , Safouane El Ghazouali , Francesca Venturini , Vida Groznik , Umberto Michelucci

Head MRI pre-processing involves converting raw images to an intensity-normalized, skull-stripped brain in a standard coordinate space. In this paper, we propose an end-to-end weakly supervised learning approach, called Neural…

Image and Video Processing · Electrical Eng. & Systems 2023-03-23 Xinzi He , Alan Wang , Mert R. Sabuncu

Neuropixels probes, initially developed for use in small animal models, have transformed basic neuroscience by enabling high-density, single-cell resolution recordings across multiple brain regions simultaneously. The recent development of…

We release NSD-Imagery, a benchmark dataset of human fMRI activity paired with mental images, to complement the existing Natural Scenes Dataset (NSD), a large-scale dataset of fMRI activity paired with seen images that enabled unprecedented…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Reese Kneeland , Paul S. Scotti , Ghislain St-Yves , Jesse Breedlove , Kendrick Kay , Thomas Naselaris

With the wide adoption of functional magnetic resonance imaging (fMRI) by cognitive neuroscience researchers, large volumes of brain imaging data have been accumulated in recent years. Aggregating these data to derive scientific insights…

Applications · Statistics 2020-06-01 Ming Bo Cai , Michael Shvartsman , Anqi Wu , Hejia Zhang , Xia Zhu

Aggregating multi-subject functional magnetic resonance imaging (fMRI) data is indispensable for generating valid and general inferences from patterns distributed across human brains. The disparities in anatomical structures and functional…

Machine Learning · Computer Science 2019-11-20 Weida Li , Mingxia Liu , Fang Chen , Daoqiang Zhang

The acquisition of MRI images offers a trade-off in terms of acquisition time, spatial/temporal resolution and signal-to-noise ratio (SNR). Thus, for instance, increasing the time efficiency of MRI often comes at the expense of reduced SNR.…

Computer Vision and Pattern Recognition · Computer Science 2011-10-28 Sudipto Dolui , Alan Kuurstra , Iván C. Salgado Patarroyo , Oleg V. Michailovich

Purpose: Combining multi-site diffusion MRI (dMRI) data is hindered by inter-scanner variability, which confounds subsequent analysis. Previous harmonization methods require large, matched or traveling human subjects from multiple sites,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Hwihun Jeong , Qiang Liu , Kathryn E. Keenan , Elisabeth A. Wilde , Walter Schneider , Sudhir Pathak , Anthony Zuccolotto , Lauren J. O'Donnell , Lipeng Ning , Yogesh Rathi

Normative modelling is an increasingly common statistical technique in neuroimaging that estimates population-level benchmarks in brain structure. It enables the quantification of individual deviations from expected distributions whilst…

Neurons and Cognition · Quantitative Biology 2025-10-21 Nida Alyas , Jonathan Horsley , Bethany Little , Peter N. Taylor , Yujiang Wang , Karoline Leiberg

The goal of the Human Brain Project is to develop during the next decade an infrastructure necessary for running a simulation of the entire human brain constrained by current experimental data. One of the key issues is therefore to…

Quantitative Methods · Quantitative Biology 2017-06-23 Paul Tiesinga , Rembrandt Bakker , Sean Hill , Jan G. Bjaalie

Multi-site MRI studies often suffer from site-specific variations arising from differences in methodology, hardware, and acquisition protocols, thereby compromising accuracy and reliability in clinical AI/ML tasks. We present PRISM…

Image and Video Processing · Electrical Eng. & Systems 2024-11-12 Sarang Galada , Tanurima Halder , Kunal Deo , Ram P Krish , Kshitij Jadhav

Clinical neuroimaging has recently witnessed explosive growth in data availability which brings studying heterogeneity in clinical cohorts to the spotlight. Normative modeling is an emerging statistical tool for achieving this objective.…

Head-mounted miniaturized microscopes, commonly known as miniscopes, have undergone rapid development and seen widespread adoption over the past two decades, enabling the imaging of neural activity in freely-behaving animals such as…

Neurons and Cognition · Quantitative Biology 2026-03-13 Weijian Zong , Weijian Yang

Brain stimulation is a core method in neuroscience. Numerous non-invasive brain stimulation (NIBS) techniques are currently in use in basic and clinical research, and recent advances promise the ability to non-invasively access deep brain…

Neurons and Cognition · Quantitative Biology 2021-11-02 Sebastian J Lehmann , Brian D Corneil
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