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Mendelian randomization (MR) is a widely used tool for causal inference in the presence of unmeasured confounders, which uses single nucleotide polymorphisms (SNPs) as instrumental variables to estimate causal effects. However, SNPs often…

Methodology · Statistics 2025-04-29 Ruoyu Wang , Haoyu Zhang , Xihong Lin

Recent work suggests that some auto-encoder variants do a good job of capturing the local manifold structure of the unknown data generating density. This paper contributes to the mathematical understanding of this phenomenon and helps…

Machine Learning · Computer Science 2012-07-03 Yoshua Bengio , Guillaume Alain , Salah Rifai

In this paper we present an algorithm for rapid Bayesian analysis that combines the benefits of nested sampling and artificial neural networks. The blind accelerated multimodal Bayesian inference (BAMBI) algorithm implements the MultiNest…

Instrumentation and Methods for Astrophysics · Physics 2012-03-12 Philip Graff , Farhan Feroz , Michael P. Hobson , Anthony Lasenby

The rapid advancement of deep neural networks has significantly improved various tasks, such as image and speech recognition. However, as the complexity of these models increases, so does the computational cost and the number of parameters,…

Machine Learning · Computer Science 2023-07-18 Davide Giacomini , Maeesha Binte Hashem , Jeremiah Suarez , Swarup Bhunia , Amit Ranjan Trivedi

We present a full Bayesian algorithm designed to perform automated searches of the parameter space of caustic-crossing binary-lens microlensing events. This builds on previous work implementing priors derived from Galactic models and…

Instrumentation and Methods for Astrophysics · Physics 2015-06-11 N. Kains , P. Browne , K. Horne , M. Hundertmark , A. Cassan

Simulation-based inference (SBI) with neural posterior estimation (NPE) provides rapid X-ray spectral fitting in both Gaussian and Poisson regimes by learning approximate parameter posteriors from simulations. We investigate auto-encoders…

Instrumentation and Methods for Astrophysics · Physics 2026-04-22 Didier Barret , Simon Dupourqué

This paper presents a joint blinding and deblinding strategy for inference of physical laws from astronomical data. The strategy allows for up to three blinding stages, where the data may be blinded, the computations of theoretical physics…

Cosmology and Nongalactic Astrophysics · Physics 2020-01-15 Elena Sellentin

The number density of galaxy clusters across mass and redshift has been established as a powerful cosmological probe. Cosmological analyses with galaxy clusters traditionally employ scaling relations. However, many challenges arise from…

Cosmology and Nongalactic Astrophysics · Physics 2025-01-08 M. Kosiba , N. Cerardi , M. Pierre , F. Lanusse , C. Garrel , N. Werner , M. Shalak

Inference after model selection presents computational challenges when dealing with intractable conditional distributions. Markov chain Monte Carlo (MCMC) is a common method for sampling from these distributions, but its slow convergence…

Methodology · Statistics 2023-08-22 Sifan Liu

The resolution of optical imaging is classically limited by the width of the point-spread function, which in turn is determined by the Rayleigh length. Recently, spatial-mode demultiplexing (SPADE) has been proposed as a method to achieve…

Quantum Physics · Physics 2025-02-26 Giuseppe Buonaiuto , Cosmo Lupo

Reconstructing the structure of thin films and multilayers from measurements of scattered X-rays or neutrons is key to progress in physics, chemistry, and biology. However, finding all structures compatible with reflectometry data is…

Estimation of optical aberrations from volumetric intensity images is a key step in sensorless adaptive optics for 3D microscopy. Recent approaches based on deep learning promise accurate results at fast processing speeds. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Debayan Saha , Uwe Schmidt , Qinrong Zhang , Aurelien Barbotin , Qi Hu , Na Ji , Martin J. Booth , Martin Weigert , Eugene W. Myers

Scanning microscopy systems, such as confocal and multiphoton microscopy, are powerful imaging tools for probing deep into biological tissue. However, scanning systems have an inherent trade-off between acquisition time, field of view,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Cassandra Tong Ye , Jiashu Han , Kunzan Liu , Anastasios Angelopoulos , Linda Griffith , Kristina Monakhova , Sixian You

By reducing variance induced by gravitational lensing, likelihood-based de-lensing techniques have true potential to extract significantly more information from deep and high-resolution Cosmic Microwave Background (CMB) data than…

Cosmology and Nongalactic Astrophysics · Physics 2025-03-13 Julien Carron

Convolutional Neural Network models have successfully detected retinal illness from optical coherence tomography (OCT) and fundus images. These CNN models frequently rely on vast amounts of labeled data for training, difficult to obtain,…

Computer Vision and Pattern Recognition · Computer Science 2022-01-28 Sourya Dipta Das , Saikat Dutta , Nisarg A. Shah , Dwarikanath Mahapatra , Zongyuan Ge

To perform high speed tasks, sensors of autonomous cars have to provide as much information in as few time steps as possible. However, radars, one of the sensor modalities autonomous cars heavily rely on, often only provide sparse, noisy…

Computer Vision and Pattern Recognition · Computer Science 2019-04-02 Daniel Bauer , Lars Kuhnert , Lutz Eckstein

In this paper, we propose a novel framework for the smart healthcare system, where we employ the compressed sensing (CS) and the combination of the state-of-the-art machine learning based denoiser as well as the alternating direction of…

Computer Vision and Pattern Recognition · Computer Science 2020-04-08 Abrar Zahin , Le Thanh Tan , Rose Qingyang Hu

We analyze photometric observations of stars, which experienced microlensing events at the considered time, in order to compare the efficiency of detecting exoplanets in observations performed at thirteen different telescopes and with…

Earth and Planetary Astrophysics · Physics 2025-09-24 S. I. Ipatov

Observations from ground based telescopes are affected by the presence of the Earth atmosphere, which severely perturbs them. The use of adaptive optics techniques has allowed us to partly beat this limitation. However, image selection or…

Instrumentation and Methods for Astrophysics · Physics 2021-02-17 A. Asensio Ramos , N. Olspert
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