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Ptychography, a prevalent imaging technique in fields such as biology and optics, poses substantial challenges in its reconstruction process, characterized by nonconvexity and large-scale requirements. This paper presents a novel approach…

Numerical Analysis · Mathematics 2024-03-25 Kevin Bui , Zichao Di

Topology Optimization (TO) holds the promise of designing next-generation compact and efficient fluidic devices. However, the inherent complexity of fluid-based TO systems, characterized by multiphysics nonlinear interactions, poses…

Computational Engineering, Finance, and Science · Computer Science 2025-08-26 Rahul Kumar Padhy , Krishnan Suresh , Aaditya Chandrasekhar

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang

Fourier ptychography is a new computational microscopy technique that provides gigapixel-scale intensity and phase images with both wide field-of-view and high resolution. By capturing a stack of low-resolution images under different…

Automatic differentiation (AD) in reverse mode (RAD) is a central component of deep learning and other uses of large-scale optimization. Commonly used RAD algorithms such as backpropagation, however, are complex and stateful, hindering deep…

Programming Languages · Computer Science 2018-10-03 Conal Elliott

Fourier ptychography is a recently explored imaging method for overcoming the diffraction limit of conventional cameras with applications in microscopy and yielding high-resolution images. In order to splice together low-resolution images…

Image and Video Processing · Electrical Eng. & Systems 2020-03-18 Yican Chen , Zhi Luo , Xia Wu , Huidong Yang , Bo Huang

Adaptive optics (AO) are reconfigurable devices that compensate for wavefront distortions or aberrations in optical systems such as microscopes, telescopes and ophthalmoscopes. Aberrations have detrimental effects that can reduce imaging…

Optics · Physics 2025-06-10 Biwei Zhang , Martin J. Booth , Qi Hu

Ptychography has risen as a reference X-ray imaging technique: it achieves resolutions of one billionth of a meter, macroscopic field of view, or the capability to retrieve chemical or magnetic contrast, among other features. A…

Optimization and Control · Mathematics 2019-06-10 Huibin Chang , Pable Enfedaque , Stefano Marchesini

We demonstrate that automatic differentiation (AD), which has become commonly available in machine learning frameworks, is an efficient way to explore ideas that lead to algorithmic improvement in multi-scale affine image registration and…

Optimization and Control · Mathematics 2025-08-05 Warin Watson , Cash Cherry , Rachelle Lang

Blind ptychography is the scanning version of coherent diffractive imaging which seeks to recover both the object and the probe simultaneously. Based on alternating minimization by Douglas-Rachford splitting, AMDRS is a blind ptychographic…

Computer Vision and Pattern Recognition · Computer Science 2018-10-31 A. Fannjiang , Z. Zhang

Autonomous science platforms which make decisions on the fly are fundamentally changing the outlook for materials development. AI-driven schemes can effectively reduce the total number of iterations needed to arrive at the best…

Ptychography is a well-studied phase imaging method that makes non-invasive imaging possible at a nanometer scale. It has developed into a mainstream technique with various applications across a range of areas such as material science or…

Image and Video Processing · Electrical Eng. & Systems 2022-08-01 Semih Barutcu , Aggelos K. Katsaggelos , Doğa Gürsoy

Ptychography is an imaging technique in which a localized illumination scans overlapping regions of an object and generates a set of diffraction intensities used to computationally reconstruct its complex-valued transmission function. We…

Quantum Physics · Physics 2019-12-18 Mário Foganholi Fernandes , Leonardo Neves

Electron ptychography provides new opportunities to resolve atomic structures with deep sub-angstrom spatial resolution and studying electron-beam sensitive materials with high dose efficiency. In practice, obtaining accurate ptychography…

Materials Science · Physics 2022-04-26 Michael C. Cao , Zhen Chen , Yi Jiang , Yimo Han

CDI is a lensless imaging technique that enables atomic-resolution imaging of non-crystalline specimens and their dynamics. However, its broader implementation has been hindered by the instability and ill-posedness of its reconstruction…

Optics · Physics 2025-12-11 Zhe Hu , Zisheng Yao , Yuhe Zhang , Pablo Villanueva-Perez

Deep learning has seen tremendous success over the past decade in computer vision, machine translation, and gameplay. This success rests in crucial ways on gradient-descent optimization and the ability to learn parameters of a neural…

Machine Learning · Computer Science 2019-08-30 Fei Wang , Daniel Zheng , James Decker , Xilun Wu , Grégory M. Essertel , Tiark Rompf

Ptychography is a coherent diffraction imaging method that uses phase retrieval techniques to reconstruct complex-valued images. It achieves this by sequentially illuminating overlapping regions of a sample with a coherent beam and…

Image and Video Processing · Electrical Eng. & Systems 2024-12-04 Alexander Denker , Johannes Hertrich , Zeljko Kereta , Silvia Cipiccia , Ecem Erin , Simon Arridge

Ptychography, a special case of the phase retrieval problem, is a popular method in modern imaging. Its measurements are based on the shifts of a locally supported window function. In general, direct recovery of an object from such…

Numerical Analysis · Mathematics 2020-10-28 Anton Forstner , Felix Krahmer , Oleh Melnyk , Nada Sissouno

This article presents a method to perform diffraction tomography in a standard microscope that includes an LED array for illumination. After acquiring a sequence of intensity-only images of a thick sample, a ptychography-based…

Optics · Physics 2015-10-30 Roarke Horstmeyer , Changhuei Yang

Automatic differentiation (AD), a technique for constructing new programs which compute the derivative of an original program, has become ubiquitous throughout scientific computing and deep learning due to the improved performance afforded…

Machine Learning · Computer Science 2023-01-10 Gaurav Arya , Moritz Schauer , Frank Schäfer , Chris Rackauckas