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Ptychography is an imaging technique which involves a sample being illuminated by a coherent, localized probe of illumination. When the probe interacts with the sample, the light is diffracted and a diffraction pattern is detected. Then the…

Numerical Analysis · Mathematics 2023-01-31 Mark Iwen , Michael Perlmutter , Mark Philip Roach

Computational methods are driving high impact microscopy techniques such as ptychography. However, the design and implementation of new algorithms is often a laborious process, as many parts of the code are written in close-to-the-hardware…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Francesco Guzzi , George Kourousias , Fulvio Billè , Roberto Pugliese , Alessandra Gianoncelli , Sergio Carrato

Ptychography promises diffraction limited resolution without the need for high resolution lenses. To achieve high resolution one has to solve the phase problem for many partially overlapping frames. Here we review some of the existing…

Optics · Physics 2012-09-24 C. Yang , J. Qian , A. Schirotzek , F. Maia , S. Marchesini

Ptychography is a powerful imaging technique that is used in a variety of fields, including materials science, biology, and nanotechnology. However, the accuracy of the reconstructed ptychography image is highly dependent on the accuracy of…

Applied Physics · Physics 2024-06-03 Ming Du , Tao Zhou , Junjing Deng , Daniel J. Ching , Steven Henke , Mathew J. Cherukara

Ptychography is a scanning coherent diffractive imaging technique that enables imaging nanometer-scale features in extended samples. One main challenge is that widely used iterative image reconstruction methods often require significant…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Canberk Ekmekci , Tekin Bicer , Zichao Wendy Di , Junjing Deng , Mujdat Cetin

We report the implementation of a fully on-chip, lensless microscopy technique termed optofluidic ptychography. This imaging modality complements the miniaturization provided by microfluidics and allows the integration of ptychographic…

Instrumentation and Detectors · Physics 2021-12-21 Pengming Song , Chengfei Guo , Shaowei Jiang , Tianbo Wang , Patrick Hu , Derek Hu , Zibang Zhang , Bin Feng , Guoan Zheng

We demonstrate a motion-free intensity diffraction tomography technique that enables direct inversion of 3D phase and absorption from intensity-only measurements for weakly scattering samples. We derive a novel linear forward model,…

Image and Video Processing · Electrical Eng. & Systems 2018-06-26 Ruilong Ling , Waleed Tahir , Hsing-Ying Lin , Hakho Lee , Lei Tian

Ptychographic phase retrieval enables high-resolution imaging of complex samples but often suffers from artifacts such as grid pathology and multislice crosstalk, which degrade reconstructed images. We propose a plug-and-play (PnP)…

Graphics · Computer Science 2026-05-26 Ming Du , Volker Rose , Junjing Deng , Dileep Singh , Si Chen , Mathew J. Cherukara

Ptychography is an attractive advance of coherent diffraction imaging (CDI), which can provide high lateral resolution and wide field of view. The theoretical resolution of ptychography is dose-limited, therefore making ptychography…

Biological Physics · Physics 2025-01-09 Huixiang Lin , Fucai Zhang

Label-free tomographic microscopy offers a compelling means to visualize three-dimensional (3D) refractive index (RI) distributions from two-dimensional (2D) intensity measurements. However, limited forward-model accuracy and the ill-posed…

Optics · Physics 2025-02-27 Delong Yang , Shaohui Zhang , Jiasong Sun , Chao Zuo , Qun Hao

In this work, we demonstrate that the ptychographic phase problem can be solved in a live fashion during scanning, while data is still being collected. We propose a generally applicable modification of the widespread projection-based…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Simon Welker , Tal Peer , Henry N. Chapman , Timo Gerkmann

Lensless in-line holography is a simple, portable, and cost-effective method of imaging especially for the biomedical microscopy applications. We propose a multiplicative gradient descent optimization based method to obtain multi-depth…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Sanjeev Kumar , Manjunatha Mahadevappa , Pranab Kumar Dutta

Ever brighter light sources, fast parallel detectors, and advances in phase retrieval methods, have made ptychography a practical and popular imaging technique. Compared to previous techniques, ptychography provides superior robustness and…

Data Analysis, Statistics and Probability · Physics 2016-07-20 Stefano Marchesini , Hari Krishnan , Benedikt J. Daurer , David A. Shapiro , Talita Perciano , James A. Sethian , Filipe R. N. C. Maia

We present a computationally efficient expectation-maximization framework for multi-frame image deconvolution and super-resolution. Our method is well adapted for processing large scale imaging data from modern astronomical surveys. Our…

Instrumentation and Methods for Astrophysics · Physics 2025-10-07 Yashil Sukurdeep , Fausto Navarro , Tamas Budavari

Fourier ptychographic microscopy is a computational imaging technique that provides quantitative phase information and high resolution over a large field-of-view. Although the technique presents numerous advantages over conventional…

Optics · Physics 2021-09-16 Eric Li , Stuart Sherwin , Gautam Gunjala , Laura Waller

Coherent diffractive imaging (CDI) enables lensless imaging with experimental simplicity and a flexible field of view, yet its resolution is fundamentally constrained by the Abbe diffraction limit. To overcome this limitation, we introduce…

Electron microscopy (EM) images exhibit anisotropic axial resolution due to the characteristics inherent to the imaging modality, presenting challenges in analysis and downstream tasks.In this paper, we propose a diffusion-model-based…

Computer Vision and Pattern Recognition · Computer Science 2023-08-04 Kyungryun Lee , Won-Ki Jeong

We report Tensorial tomographic Fourier Ptychography (ToFu), a new non-scanning label-free tomographic microscopy method for simultaneous imaging of quantitative phase and anisotropic specimen information in 3D. Built upon Fourier…

Spectroscopic ptychography is a powerful technique to determine the chemical composition of a sample with high spatial resolution. In spectro-ptychography, a sample is rastered through a focused x-ray beam with varying photon energy so that…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Huibin Chang , Ziqin Rong , Pablo Enfedaque , Stefano Marchesini

Ptychography is an imaging technique that captures multiple overlapping snapshots of a sample, illuminated coherently by a moving localized probe. The image recovery from ptychographic data is generally achieved via an iterative algorithm…

Image and Video Processing · Electrical Eng. & Systems 2025-10-06 Weijie Gan , Qiuchen Zhai , Michael Thompson McCann , Cristina Garcia Cardona , Ulugbek S. Kamilov , Brendt Wohlberg