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Related papers: Data Transfer Approaches to Improve Seq-to-Seq Ret…

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Using transfer learning to adapt a pre-trained "source model" to a downstream "target task" can dramatically increase performance with seemingly no downside. In this work, we demonstrate that there can exist a downside after all: bias…

Machine Learning · Computer Science 2022-07-07 Hadi Salman , Saachi Jain , Andrew Ilyas , Logan Engstrom , Eric Wong , Aleksander Madry

Mixture models arise in many regression problems, but most methods have seen limited adoption partly due to these algorithms' highly-tailored and model-specific nature. On the other hand, transformers are flexible, neural sequence models…

Machine Learning · Computer Science 2023-11-15 Reese Pathak , Rajat Sen , Weihao Kong , Abhimanyu Das

Diffusion models have been successfully adapted to text generation tasks by mapping the discrete text into the continuous space. However, there exist nonnegligible gaps between training and inference, owing to the absence of the forward…

Computation and Language · Computer Science 2023-05-09 Zecheng Tang , Pinzheng Wang , Keyan Zhou , Juntao Li , Ziqiang Cao , Min Zhang

Recurrent neural networks are effective models to process sequences. However, they are unable to learn long-term dependencies because of their inherent sequential nature. As a solution, Vaswani et al. introduced the Transformer, a model…

Machine Learning · Computer Science 2023-03-28 Quentin Fournier , Gaétan Marceau Caron , Daniel Aloise

Retrosynthesis, which predicts the reactants of a given target molecule, is an essential task for drug discovery. In recent years, the machine learing based retrosynthesis methods have achieved promising results. In this work, we introduce…

Artificial Intelligence · Computer Science 2023-06-08 Shufang Xie , Rui Yan , Junliang Guo , Yingce Xia , Lijun Wu , Tao Qin

Retrosynthesis reaction prediction aims to infer plausible reactant molecules for a given product and is a important problem in computer-aided organic synthesis. Despite recent progress, many existing models still fall short of the accuracy…

Machine Learning · Computer Science 2025-12-16 Youjun Zhao

The growing use of Machine Learning has produced significant advances in many fields. For image-based tasks, however, the use of deep learning remains challenging in small datasets. In this article, we review, evaluate and compare the…

Machine Learning · Computer Science 2021-06-09 Miguel Romero , Yannet Interian , Timothy Solberg , Gilmer Valdes

Effectively learning from sequential data is a longstanding goal of Artificial Intelligence, especially in the case of long sequences. From the dawn of Machine Learning, several researchers have pursued algorithms and architectures capable…

Machine Learning · Computer Science 2025-08-19 Matteo Tiezzi , Michele Casoni , Alessandro Betti , Marco Gori , Stefano Melacci

Transfer learning is a useful technique for achieving improved performance and reducing training costs by leveraging the knowledge gained from source tasks and applying it to target tasks. Assessing the effectiveness of transfer learning…

Machine Learning · Computer Science 2023-06-12 Peizhong Ju , Sen Lin , Mark S. Squillante , Yingbin Liang , Ness B. Shroff

The availability of abundant labeled data in recent years led the researchers to introduce a methodology called transfer learning, which utilizes existing data in situations where there are difficulties in collecting new annotated data.…

Machine Learning · Computer Science 2021-04-07 Abolfazl Farahani , Behrouz Pourshojae , Khaled Rasheed , Hamid R. Arabnia

Recently, template-based (TB) and template-free (TF) molecule graph learning methods have shown promising results to retrosynthesis. TB methods are more accurate using pre-encoded reaction templates, and TF methods are more scalable by…

Machine Learning · Computer Science 2022-02-17 Zhangyang Gao , Cheng Tan , Lirong Wu , Stan Z. Li

Accurate phenotype prediction from RNA sequencing (RNA-seq) data is essential for diagnosis, biomarker discovery, and personalized medicine. Deep learning models have demonstrated strong potential to outperform classical machine learning…

Machine Learning · Computer Science 2026-03-10 Kevin Dradjat , Massinissa Hamidi , Blaise Hanczar

With the emergence of large-scale pre-trained neural networks, methods to adapt such "foundation" models to data-limited downstream tasks have become a necessity. Fine-tuning, preference optimization, and transfer learning have all been…

Machine Learning · Statistics 2025-07-09 Javan Tahir , Surya Ganguli , Grant M. Rotskoff

Transfer learning enhances model performance in a target population with limited samples by leveraging knowledge from related studies. While many works focus on improving predictive performance, challenges of statistical inference persist.…

Methodology · Statistics 2024-12-05 Daoyuan Lai , Oscar Hernan Madrid Padilla , Tian Gu

There is an increasing number of pre-trained deep neural network models. However, it is still unclear how to effectively use these models for a new task. Transfer learning, which aims to transfer knowledge from source tasks to a target…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Yunhui Guo , Yandong Li , Liqiang Wang , Tajana Rosing

Pre-trained machine learning (ML) models have shown great performance for a wide range of applications, in particular in natural language processing (NLP) and computer vision (CV). Here, we study how pre-training could be used for…

Machine Learning · Computer Science 2024-01-05 Shashank Subramanian , Peter Harrington , Kurt Keutzer , Wahid Bhimji , Dmitriy Morozov , Michael Mahoney , Amir Gholami

Transfer learning provides an effective solution for feasibly and fast customize accurate \textit{Student} models, by transferring the learned knowledge of pre-trained \textit{Teacher} models over large datasets via fine-tuning. Many…

Machine Learning · Computer Science 2020-08-11 Shuo Wang , Surya Nepal , Carsten Rudolph , Marthie Grobler , Shangyu Chen , Tianle Chen

Transfer learning can significantly improve the sample efficiency of neural networks, by exploiting the relatedness between a data-scarce target task and a data-abundant source task. Despite years of successful applications, transfer…

Machine Learning · Computer Science 2023-06-06 Federica Gerace , Luca Saglietti , Stefano Sarao Mannelli , Andrew Saxe , Lenka Zdeborová

Datasets in the Natural Sciences are often curated with the goal of aiding scientific understanding and hence may not always be in a form that facilitates the application of machine learning. In this paper, we identify three trends within…

Chemical Physics · Physics 2021-05-07 Ryan-Rhys Griffiths , Philippe Schwaller , Alpha A. Lee

Diffusion models have recently emerged as powerful generative priors for solving inverse problems. However, training diffusion models in the pixel space are both data-intensive and computationally demanding, which restricts their…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Bowen Song , Soo Min Kwon , Zecheng Zhang , Xinyu Hu , Qing Qu , Liyue Shen
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