Related papers: High-throughput molecular imaging via deep learnin…
Hyperspectral imaging is a rich source of data, allowing for multitude of effective applications. However, such imaging remains challenging because of large data dimension and, typically, small pool of available training examples. While…
Coherent Raman scattering provides highly sensitive vibrational analysis through nonlinear light-matter interactions. However, its application to metal interfaces has remained challenging because the intrinsically large non-resonant…
In spectroscopic experiments, data acquisition in multi-dimensional phase space may require long acquisition time, owing to the large phase space volume to be covered. In such case, the limited time available for data acquisition can be a…
In general, most of the substances in nature exist in mixtures, and the noninvasive identification of mixture composition with high speed and accuracy remains a difficult task. However, the development of Raman spectroscopy, machine…
Raman spectroscopy is a widely-used non-destructive material characterization method, which provides information about the vibrational modes of the material and therefore of its atomic structure and chemical composition. Interpretation of…
Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…
Learning-based single image super-resolution (SISR) methods are continuously showing superior effectiveness and efficiency over traditional model-based methods, largely due to the end-to-end training. However, different from model-based…
To develop a deep-learning method for achieving fast high-resolution MR elastography from highly undersampled data without the need of high-quality training dataset. We first framed the deep neural network representation as a nonlinear…
Biomedical imaging is unequivocally dependent on the ability to reconstruct interpretable and high-quality images from acquired sensor data. This reconstruction process is pivotal across many applications, spanning from magnetic resonance…
Raman spectroscopy provides spectral information related to the specific molecular structures of substances and has been well established as a powerful tool for studying biological tissues and diagnosing diseases. This article reviews…
Hyperspectral imaging provides precise classification for land use and cover due to its exceptional spectral resolution. However, the challenges of high dimensionality and limited spatial resolution hinder its effectiveness. This study…
In many scientific applications, measured time series are corrupted by noise or distortions. Traditional denoising techniques often fail to recover the signal of interest, particularly when the signal-to-noise ratio is low or when certain…
This paper presents a deep learning method for faster magnetic resonance imaging (MRI) by reducing k-space data with sub-Nyquist sampling strategies and provides a rationale for why the proposed approach works well. Uniform subsampling is…
Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM) is a highly sensitive QPI method, due to its partially coherent illumination and common path…
We introduce HAMscope, a compact, snapshot hyperspectral autofluorescence miniscope that enables real-time, label-free molecular imaging in a wide range of biological systems. By integrating a thin polymer diffuser into a widefield…
Ultrafast lasers have become one of the most powerful tools in coherent nonlinear optical spectroscopy. Short pulses enable direct observation of fast molecular dynamics, whereas broad spectral bandwidth offers ways of controlling nonlinear…
Radio interferometry invariably suffers from an incomplete coverage of the spatial Fourier space, which leads to imaging artifacts. The current state-of-the-art technique is to create an image by Fourier-transforming the incomplete…
Hyperspectral imaging captures both spectral and spatial information from a sample. The near infrared (NIR, > 800 nm) is advantageous for biomedical imaging as it falls into the tissue transparency window but also contains vibrational…
Raman spectroscopy's capability to provide meaningful composition predictions is heavily reliant on a pre-processing step to remove insignificant spectral variation. This is crucial in biofluid analysis. Widespread adoption of diagnostics…
Infrared (IR) microscopes measure spectral information that quantifies molecular content to assign the identity of biomedical cells but lack the spatial quality of optical microscopy to appreciate morphologic features. Here, we propose a…