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The increasing availability of large collections of electronic health record (EHR) data and unprecedented technical advances in deep learning (DL) have sparked a surge of research interest in developing DL based clinical decision support…

Machine Learning · Computer Science 2021-12-07 Di Jin , Elena Sergeeva , Wei-Hung Weng , Geeticka Chauhan , Peter Szolovits

In this work, we propose an AI-based method that intends to improve the conventional retinal disease treatment procedure and help ophthalmologists increase diagnosis efficiency and accuracy. The proposed method is composed of a deep neural…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Jia-Hong Huang , Chao-Han Huck Yang , Fangyu Liu , Meng Tian , Yi-Chieh Liu , Ting-Wei Wu , I-Hung Lin , Kang Wang , Hiromasa Morikawa , Hernghua Chang , Jesper Tegner , Marcel Worring

Optical coherence tomography (OCT) helps ophthalmologists assess macular edema, accumulation of fluids, and lesions at microscopic resolution. Quantification of retinal fluids is necessary for OCT-guided treatment management, which relies…

Image and Video Processing · Electrical Eng. & Systems 2022-12-15 Reza Rasti , Armin Biglari , Mohammad Rezapourian , Ziyun Yang , Sina Farsiu

Explainability is a key requirement for computer-aided diagnosis systems in clinical decision-making. Multiple instance learning with attention pooling provides instance-level explainability, however for many clinical applications a deeper,…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Ario Sadafi , Oleksandra Adonkina , Ashkan Khakzar , Peter Lienemann , Rudolf Matthias Hehr , Daniel Rueckert , Nassir Navab , Carsten Marr

Attribution methods are an easy to use tool for investigating and validating machine learning models. Multiple methods have been suggested in the literature and it is not yet clear which method is most suitable for a given task. In this…

Image and Video Processing · Electrical Eng. & Systems 2019-09-20 Fabian Eitel , Kerstin Ritter

In this paper, we propose two distinct solutions to the problem of Diabetic Retinopathy (DR) classification. In the first approach, we introduce a shallow neural network architecture. This model performs well on classification of the most…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Hangwei Zhuang , Nabil Ettehadi

Diabetic Retinopathy (DR) is a leading cause of vision loss in the world,. In the past few Diabetic Retinopathy (DR) is a leading cause of vision loss in the world. In the past few years, Artificial Intelligence (AI) based approaches have…

Image and Video Processing · Electrical Eng. & Systems 2021-07-02 Vasudevan Lakshminarayanan , Hoda Kherdfallah , Arya Sarkar , J. Jothi Balaji

Diabetic Retinopathy (DR) is an eye disease which arises due to diabetes mellitus. It might cause vision loss and blindness. To prevent irreversible vision loss, early detection through systematic screening is crucial. Although researchers…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Aruna Jithesh , Chinmayi Karumuri , Venkata Kiran Reddy Kotha , Meghana Doddapuneni , Taehee Jeong

The study of the attribution of input features to the output of neural network models is an active area of research. While numerous Explainable AI (XAI) techniques have been proposed to interpret these models, the systematic and automated…

Computation and Language · Computer Science 2026-03-13 Aria Nourbakhsh , Salima Lamsiyah , Adelaide Danilov , Christoph Schommer

Diabetic retinopathy (DR) is a complication of diabetes and usually takes decades to reach sight-threatening levels. Accurate and robust detection of DR severity is critical for the timely management and treatment of diabetes. However, most…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Qinkai Yu , Jianyang Xie , Anh Nguyen , He Zhao , Jiong Zhang , Huazhu Fu , Yitian Zhao , Yalin Zheng , Yanda Meng

Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Mohammad Rahimzadeh , Mahmoud Reza Mohammadi

Glaucoma is a progressive eye disease that leads to optic nerve damage, causing irreversible vision loss if left untreated. Optical coherence tomography (OCT) has become a crucial tool for glaucoma diagnosis, offering high-resolution 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-10-02 Roshan Kenia , Anfei Li , Rishabh Srivastava , Kaveri A. Thakoor

Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access to specialists. Based on the fact that fundus structure and vascular disorders are the main…

Computer Vision and Pattern Recognition · Computer Science 2018-11-05 C. -H. Huck Yang , Fangyu Liu , Jia-Hong Huang , Meng Tian , Hiromasa Morikawa , I-Hung Lin , Yi-Chieh Liu , Hao-Hsiang Yang , Jesper Tegner

Deep Learning (DL) holds enormous potential for improving medical imaging diagnostics, yet the lack of interpretability in most models hampers clinical trust and adoption. This paper presents an explainable deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Sai Teja Erukude , Viswa Chaitanya Marella , Suhasnadh Reddy Veluru

In the modern world, one of the most severe eye infections brought on by diabetes is known as diabetic retinopathy, which will result in retinal damage, and, thus, lead to blindness. Diabetic retinopathy can be well treated with early…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 V. Banupriya , S. Anusuya

Computer-aided diagnostics has benefited from the development of deep learning-based computer vision techniques in these years. Traditional supervised deep learning methods assume that the test sample is drawn from the identical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Zesheng Hong , Yubiao Yue , Yubin Chen , Lele Cong , Huanjie Lin , Yuanmei Luo , Mini Han Wang , Weidong Wang , Jialong Xu , Xiaoqi Yang , Hechang Chen , Zhenzhang Li , Sihong Xie

Diabetic Retinopathy (DR) refers to a barrier that takes place in diabetes mellitus damaging the blood vessel network present in the retina. This may endanger the subjects' vision if they have diabetes. It can take some time to perform a DR…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 V. Banupriya , S. Anusuya

In the real world, medical datasets often exhibit a long-tailed data distribution (i.e., a few classes occupy the majority of the data, while most classes have only a limited number of samples), which results in a challenging long-tailed…

Computer Vision and Pattern Recognition · Computer Science 2023-03-22 Lie Ju , Zhen Yu , Lin Wang , Xin Zhao , Xin Wang , Paul Bonnington , Zongyuan Ge

The prevalence of diabetic retinopathy (DR) has reached 34.6% worldwide and is a major cause of blindness among middle-aged diabetic patients. Regular DR screening using fundus photography helps detect its complications and prevent its…

Image and Video Processing · Electrical Eng. & Systems 2022-11-09 Fahman Saeed , Muhammad Hussain , Hatim A Aboalsamh , Fadwa Al Adel , Adi Mohammed Al Owaifeer

In this work, we propose an advanced AI based grading system for OCT images. The proposed system is a very deep fully convolutional attentive classification network trained with end to end advanced transfer learning with online random…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Mrinal Haloi