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Age-related macular degeneration (AMD) is a degenerative disorder affecting the macula, a key area of the retina for visual acuity. Nowadays, it is the most frequent cause of blindness in developed countries. Although some promising…
People with diabetes are more likely to develop diabetic retinopathy (DR) than healthy people. However, DR is the leading cause of blindness. At present, the diagnosis of diabetic retinopathy mainly relies on the experienced clinician to…
Recent advances in machine learning models have greatly increased the performance of automated methods in medical image analysis. However, the internal functioning of such models is largely hidden, which hinders their integration in…
Purpose: (1) To develop a deep learning algorithm to identify major tissue structures of the optic nerve head (ONH) in 3D optical coherence tomography (OCT) scans; (2) to exploit such information to robustly differentiate among healthy,…
One of the most serious corneal disorders, keratoconus is difficult to diagnose in its early stages and can result in blindness. This illness, which often appears in the second decade of life, affects people of all sexes and races.…
Stroke is a major public health problem, affecting millions worldwide. Deep learning has recently demonstrated promise for enhancing the diagnosis and risk prediction of stroke. However, existing methods rely on costly medical imaging…
Recently, diabetic retinopathy (DR) screening utilizing ultra-wide optical coherence tomography angiography (UW-OCTA) has been used in clinical practices to detect signs of early DR. However, developing a deep learning-based DR analysis…
Diabetic Macular Edema (DME), a prevalent complication among diabetic patients, constitutes a major cause of visual impairment and blindness. Although deep learning has achieved remarkable progress in medical image analysis, traditional DME…
We propose an automatic diabetic retinopathy (DR) analysis algorithm based on two-stages deep convolutional neural networks (DCNN). Compared to existing DCNN-based DR detection methods, the proposed algorithm have the following advantages:…
Optical Coherence Tomography (OCT) provides a unique ability to image the eye retina in 3D at micrometer resolution and gives ophthalmologist the ability to visualize retinal diseases such as Age-Related Macular Degeneration (AMD). While…
Eye is the essential sense organ for vision function. Due to the fact that certain eye disorders might result in vision loss, it is essential to diagnose and treat eye diseases early on. By identifying common eye illnesses and performing an…
Background: RETFound, a self-supervised, retina-specific foundation model (FM), showed potential in downstream applications. However, its comparative performance with traditional deep learning (DL) models remains incompletely understood.…
Diabetic retinopathy is a leading cause of vision loss among adults and a major global health challenge, particularly in underserved regions. This study presents PerceptronCARE, a deep learning-based teleophthalmology application designed…
Explaining deep learning models is essential for clinical integration of medical image analysis systems. A good explanation highlights if a model depends on spurious features that undermines generalization and harms a subset of patients or,…
Clinical diagnosis of the eye is performed over multifarious data modalities including scalar clinical labels, vectorized biomarkers, two-dimensional fundus images, and three-dimensional Optical Coherence Tomography (OCT) scans. Clinical…
Diabetic retinopathy (DR) is one of the major complications in diabetic patients' eyes, potentially leading to permanent blindness if not detected timely. This study aims to evaluate the accuracy of artificial intelligence (AI) in…
Self-supervised learning (SSL) has emerged as a powerful technique for improving the efficiency and effectiveness of deep learning models. Contrastive methods are a prominent family of SSL that extract similar representations of two…
Diabetic retinopathy (DR) is one of the major blindness-causing diseases currently known. Automatic grading of DR using deep learning methods not only speeds up the diagnosis of the disease but also reduces the rate of misdiagnosis.…
Diabetic Retinopathy is a global health problem, influences 100 million individuals worldwide, and in the next few decades, these incidences are expected to reach epidemic proportions. Diabetic Retinopathy is a subtle eye disease that can…
Diabetic retinopathy is a leading cause of blindness around the world and demands precise AI-based diagnostic tools. Traditional loss functions in multi-class classification, such as Categorical Cross-Entropy (CCE), are very common but…