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Poisson-Boltzmann (PB) model is one of the most popular implicit solvent models in biophysical modeling and computation. The ability of providing accurate and reliable PB estimation of electrostatic solvation free energy, $\Delta…

Biomolecules · Quantitative Biology 2016-06-10 Duc D. Nguyen , Bao Wang , Guo-wei Wei

This work concerns adaptive refinement procedures for meshes of polygonal virtual elements. Specifically, refinement procedures previously proposed by the authors for structured meshes are generalized for the challenging case of arbitrary…

Numerical Analysis · Mathematics 2023-03-31 Daniel van Huyssteen , Felipe Lopez Rivarola , Guillermo Etse , Paul Steinmann

In the present thesis, a computational framework for the analysis of the deformation and damage phenomena occurring at the micro-scale of polycrystalline materials is presented. Micro-mechanics studies are commonly performed using the…

Computational Engineering, Finance, and Science · Computer Science 2018-02-08 Vincenzo Gulizzi

We present a collection of algorithms which utilize dimensional reduction to perform mesh refinement and study possibly singular solutions of time-dependent partial differential equations. The algorithms are inspired by constructions used…

Numerical Analysis · Mathematics 2007-06-21 Panagiotis Stinis

We consider the Poisson-Boltzmann equation in a periodic cell, representative of a porous medium. It is a model for the electrostatic distribution of $N$ chemical species diluted in a liquid at rest, occupying the pore space with charged…

Analysis of PDEs · Mathematics 2015-04-24 Gregoire Allaire , Jean-Francois Dufreche , Andro Mikelic , Andrey Piatnitski

The Adaptive Poisson-Boltzmann Solver (APBS) software was developed to solve the equations of continuum electrostatics for large biomolecular assemblages that has provided impact in the study of a broad range of chemical, biological, and…

This paper introduces an approach to decoupling singularly perturbed boundary value problems for fourth-order ordinary differential equations that feature a small positive parameter $\epsilon$ multiplying the highest derivative. We…

Numerical Analysis · Mathematics 2023-06-13 Charuka D. Wickramasinghe

Partial differential equations can be solved on general polygonal and polyhedral meshes, through Polytopal Element Methods (PEMs). Unfortunately, the relation between geometry and analysis is still unknown and subject to ongoing research in…

Computational Geometry · Computer Science 2022-11-23 Daniela Cabiddu , Giuseppe Patanè , Michela Spagnuolo

Variational inequalities play a pivotal role in a wide array of scientific and engineering applications. This project presents two techniques for adaptive mesh refinement (AMR) in the context of variational inequalities, with a specific…

Numerical Analysis · Mathematics 2025-02-21 Giuliano Stefano Fochesatto

We propose a new practical adaptive refinement strategy for $hp$-finite element approximations of elliptic problems. Following recent theoretical developments in polynomial-degree-robust a posteriori error analysis, we solve two types of…

Numerical Analysis · Mathematics 2018-10-17 Patrik Daniel , Alexandre Ern , Iain Smears , Martin Vohralík

This paper presents a novel p-adaptive, high-order mesh-free framework for the accurate and efficient simulation of fluid flows in complex geometries. High-order differential operators are constructed locally for arbitrary node…

Numerical Analysis · Mathematics 2025-11-27 Ruofeng Feng , Jack R. C. King , Steven J. Lind

In this paper we present a new Eulerian finite element method for the discretization of scalar partial differential equations on evolving surfaces. In this method we use the restriction of standard space-time finite element spaces on a…

Numerical Analysis · Mathematics 2022-12-26 Hauke Sass , Arnold Reusken

We present a robust and efficient target-based mesh adaptation methodology, building on hybridized discontinuous Galerkin schemes for (nonlinear) convection-diffusion problems, including the compressible Euler and Navier-Stokes equations.…

Numerical Analysis · Mathematics 2014-11-12 Michael Woopen , Georg May , Jochen Schütz

We consider the problem of numerically approximating the solutions to a partial differential equation (PDE) when there is insufficient information to determine a unique solution. Our main example is the Poisson boundary value problem, when…

Numerical Analysis · Mathematics 2023-12-21 Peter Binev , Andrea Bonito , Albert Cohen , Wolfgang Dahmen , Ronald DeVore , Guergana Petrova

In this paper, we develop a domain decomposition method for the nonlinear Poisson-Boltzmann equation based on a solvent-excluded surface widely used in computational chemistry. The model relies on a nonlinear equation defined in…

Numerical Analysis · Mathematics 2024-04-08 Abhinav Jha , Benjamin Stamm

Unfitted (also known as embedded or immersed) finite element approximations of partial differential equations are very attractive because they have much lower geometrical requirements than standard body-fitted formulations. These schemes do…

Numerical Analysis · Mathematics 2022-04-13 Santiago Badia , Pere A. Martorell , Francesc Verdugo

Particle-in-Cell (PIC) simulations rely on accurate solutions of the electrostatic Poisson equation, yet accuracy often deteriorates near irregular Dirichlet boundaries on Cartesian meshes. While much research has addressed discretization…

Numerical Analysis · Mathematics 2026-01-14 Kai Zhang , Tao Xiao , Weizong Wang , Bijiao He

In this paper we present a new H(div)-conforming unfitted finite element method for the mixed Poisson problem which is robust in the cut configuration and preserves conservation properties of body-fitted finite element methods. The key is…

Numerical Analysis · Mathematics 2024-09-04 Christoph Lehrenfeld , Tim van Beeck , Igor Voulis

This paper presents a high-order method for solving an interface problem for the Poisson equation on embedded meshes through a coupled finite element and integral equation approach. The method is capable of handling homogeneous or…

Numerical Analysis · Mathematics 2018-08-29 Natalie N. Beams , Andreas Klöckner , Luke N. Olson

The paper is concerned with the adaptive finite element solution of linear elliptic differential equations using equidistributing meshes. A strategy is developed for defining this type of mesh based on residual-based a posteriori error…

Numerical Analysis · Mathematics 2020-04-20 Yinnian He , Weizhang Huang
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