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Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees. Substitutions in sequences are modelled through a continuous-time Markov process, characterised by an instantaneous rate matrix, which standard…

Populations and Evolution · Quantitative Biology 2020-07-20 Naomi E. Hannaford , Sarah E. Heaps , Tom M. W. Nye , Tom A. Williams , T. Martin Embley

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees relating species. Along branches, sequence evolution is modelled using a continuous-time Markov process characterised by an instantaneous rate…

A phylogenetic tree shows the evolutionary relationships among species. Internal nodes of the tree represent speciation events and leaf nodes correspond to species. A goal of phylogenetics is to combine such trees into larger trees, called…

Artificial Intelligence · Computer Science 2014-01-16 Neil C. A. Moore , Patrick Prosser

Most of major algorithms for phylogenetic tree reconstruction assume that sequences in the analyzed set either do not have any offspring, or that parent sequences can maximally mutate into just two descendants. The graph resulting from such…

Populations and Evolution · Quantitative Biology 2013-10-09 Piotr Plonski , Jan P. Radomski

Phylogenetic tree shapes capture fundamental signatures of evolution. We consider ``ranked'' tree shapes, which are equipped with a total order on the internal nodes compatible with the tree graph. Recent work has established an elegant…

Populations and Evolution · Quantitative Biology 2026-03-10 Chris Jennings-Shaffer , Ziyue , Chen , Julia A Palacios , Frederick A Matsen

Distance-based approaches in phylogenetics such as Neighbor-Joining are a fast and popular approach for building trees. These methods take pairs of sequences from them construct a value that, in expectation, is additive under a stochastic…

Populations and Evolution · Quantitative Biology 2008-08-21 Mike Steel

The conception of multi-alphabetical genetics is represented. Matrix forms of the representation of the multi-level system of molecular-genetic alphabets have revealed algebraic properties of this system. These properties are connected with…

Other Quantitative Biology · Quantitative Biology 2013-01-18 Sergey V. Petoukhov

Phylogenetic networks generalise phylogenetic trees and allow for the accurate representation of the evolutionary history of a set of present-day species whose past includes reticulate events such as hybridisation and lateral gene transfer.…

Populations and Evolution · Quantitative Biology 2018-09-05 Joan Carles Pons , Charles Semple , Mike Steel

Motivated by applications to low-rank matrix completion, we give a combinatorial characterization of the independent sets in the algebraic matroid associated to the collection of $m\times n$ rank-2 matrices and $n\times n$ skew-symmetric…

Combinatorics · Mathematics 2017-07-17 Daniel Irving Bernstein

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

The supertree construction problem is about combining several phylogenetic trees with possibly conflicting information into a single tree that has all the leaves of the source trees as its leaves and the relationships between the leaves are…

Computational Engineering, Finance, and Science · Computer Science 2020-02-19 Laura Koponen , Emilia Oikarinen , Tomi Janhunen , Laura Säilä

A dynamical picture of phylogenetic evolution is given in terms of Markov models on a state space, comprising joint probability distributions for character types of taxonomic classes. Phylogenetic branching is a process which augments the…

Populations and Evolution · Quantitative Biology 2009-11-10 P. D. Jarvis , J. D. Bashford , J. G. Sumner

Phylogenetic trees are a central tool in understanding evolution. They are typically inferred from sequence data, and capture evolutionary relationships through time. It is essential to be able to compare trees from different data sources…

Populations and Evolution · Quantitative Biology 2017-10-31 Michelle Kendall , Caroline Colijn

Motivated by a concept studied in [1], we consider a property of matrices over finite fields that generalizes triangular totally nonsingular matrices to block matrices. We show that (1) matrices with this property suffice to construct good…

Information Theory · Computer Science 2020-12-08 Pavel Pudlák

Recent work has discussed the importance of multiplicative closure for the Markov models used in phylogenetics. For continuous-time Markov chains, a sufficient condition for multiplicative closure of a model class is ensured by demanding…

Populations and Evolution · Quantitative Biology 2012-04-24 Jeremy Sumner , Jesus Fernandez-Sanchez , Peter Jarvis

Phylogenetic trees and networks are leaf-labelled graphs used to model evolution. Display graphs are created by identifying common leaf labels in two or more phylogenetic trees or networks. The treewidth of such graphs is bounded as a…

Data Structures and Algorithms · Computer Science 2018-09-05 Remie Janssen , Mark Jones , Steven Kelk , Georgios Stamoulis , Taoyang Wu

We consider the reconciliation problem, in which the task is to find a mapping of a gene tree into a species tree, so as to maximize the likelihood of such fitting, given the available data. We describe a model for the evolution of the…

Populations and Evolution · Quantitative Biology 2023-11-09 Albert C. Soewongsono , Jiahao Diao , Tristan Stark , Amanda E. Wilson , David A. Liberles , Barbara R. Holland , Malgorzata M. O'Reilly

The aim of this review is to present and analyze the probabilistic models of mathematical phylogenetics which have been intensively used in recent years in biology as the cornerstone of attempts to infer and reconstruct the ancestral…

Populations and Evolution · Quantitative Biology 2020-01-08 Peter D Jarvis , Jeremy G Sumner

Recent work has proven the existence of extreme inbreeding in a European ancestry sample taken from the contemporary UK population \cite{nature_01}. This result brings our attention again to a math problem related to inbreeding family trees…

Populations and Evolution · Quantitative Biology 2021-09-08 C. Jarne , F A. Gómez Albarracín , M. Caruso

The rates-across-sites assumption in phylogenetic inference posits that the rate matrix governing the Markovian evolution of a character on an edge of the putative phylogenetic tree is the product of a character-specific scale factor and a…

Populations and Evolution · Quantitative Biology 2007-05-23 Steven N. Evans , Tandy Warnow
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