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Receiver operating characteristic (ROC) analysis is a tool to evaluate the capacity of a numeric measure to distinguish between groups, often employed in the evaluation of diagnostic tests. Overall classification ability is sometimes…

Optimal performance is critical for decision-making tasks from medicine to autonomous driving, however common performance measures may be too general or too specific. For binary classifiers, diagnostic tests or prognosis at a timepoint,…

The Receiver Operating Characteristic (ROC) curve and the Area Under the Curve (AUC) of the ROC curve are widely used to compare the performance of diagnostic and prognostic assays. The ROC curve has the advantage that it is independent of…

When evaluating medical tests or biomarkers for disease classification, the area under the receiver-operating characteristic (ROC) curve is a widely used performance metric that does not require us to commit to a specific decision…

Methodology · Statistics 2013-10-21 Wanhua Su , Yan Yuan , Mu Zhu

Objectives: This study provides an effective model selection method based on the empirical likelihood approach for constructing summary receiver operating characteristic (sROC) curves from meta-analyses of diagnostic studies. Methods: We…

Methodology · Statistics 2018-03-13 ShengLi Tzeng , Chun-Shu Chen , Yu-Fen Li , Jin-Hua Chen

Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between diseased and nondiseased states must be…

Methodology · Statistics 2018-06-05 Vanda Inacio de Carvalho , Maria Xose Rodriguez-Alvarez

The Receiver Operating Characteristic (ROC) curve is a useful tool that measures the discriminating power of a continuous variable or the accuracy of a pharmaceutical or medical test to distinguish between two conditions or classes. In…

Methodology · Statistics 2022-07-26 Ana M. Bianco , Graciela Boente , Wenceslao Gonzalez-Manteiga

The increasing use of automated translation quality estimation (QE) systems calls for practical, decision-oriented methods for evaluating their performance. We propose that Receiver Operating Characteristic (ROC) analysis is a useful…

Computation and Language · Computer Science 2026-05-26 Evelyn Y. Garland , Carola F. Berger

Verification bias is a well-known problem that may occur in the evaluation of predictive ability of diagnostic tests. When a binary disease status is considered, various solutions can be found in the literature to correct inference based on…

Methodology · Statistics 2023-04-10 Khanh To Duc , Monica Chiogna , Gianfranco Adimari

We propose new simultaneous inference methods for diagnostic trials with elaborate factorial designs. Instead of the commonly used total area under the receiver operating characteristic (ROC) curve, our parameters of interest are partial…

Statistics Theory · Mathematics 2023-02-22 Maximilian Wechsung , Frank Konietschke

Whilst the size and complexity of ML models have rapidly and significantly increased over the past decade, the methods for assessing their performance have not kept pace. In particular, among the many potential performance metrics, the ML…

Machine Learning · Computer Science 2023-12-29 Michael Roberts , Alon Hazan , Sören Dittmer , James H. F. Rudd , Carola-Bibiane Schönlieb

The integration of artificial intelligence (AI) into medical diagnostic workflows requires robust and consistent evaluation methods to ensure reliability, clinical relevance, and the inherent variability in expert judgments. Traditional…

The accuracy of a diagnostic test is typically characterised using the receiver operating characteristic (ROC) curve. Summarising indexes such as the area under the ROC curve (AUC) are used to compare different tests as well as to measure…

Methodology · Statistics 2010-12-30 Fang Yao , Radu V. Craiu , Benjamin Reiser

In this review, we present an overview of the main aspects related to the statistical evaluation of medical tests for diagnosis and prognosis. Measures of diagnostic performance for binary tests, such as sensitivity, specificity, and…

Methodology · Statistics 2020-07-16 Vanda Inacio , Maria Xose Rodriguez-Alvarez , Pilar Gayoso-Diz

This article considers the receiver operating characteristic (ROC) curve analysis for medical data with non-ignorable missingness in the disease status. In the framework of the logistic regression models for both the disease status and the…

Methodology · Statistics 2024-11-27 Dingding Hu , Tao Yu , Pengfei Li

A myriad of measures to illustrate performance of predictive artificial intelligence (AI) models have been proposed in the literature. Selecting appropriate performance measures is essential for predictive AI models that are developed to be…

Many algorithms have been proposed to help clinicians evaluate cone density and spacing, as these may be related to the onset of retinal diseases. However, there has been no rigorous comparison of the performance of these algorithms. In…

Medical Physics · Physics 2015-03-13 Letizia Mariotti , Nicholas Devaney

Online and AI-based symptom checkers are applications that assist medical laypeople in diagnosing their symptoms and determining which course of action to take. When evaluating these tools, previous studies primarily used an approach…

Human-Computer Interaction · Computer Science 2025-06-30 Marvin Kopka , Markus A. Feufel

This paper proposes a statistical framework of using artificial intelligence to improve human decision making. The performance of each human decision maker is benchmarked against that of machine predictions. We replace the diagnoses made by…

Econometrics · Economics 2024-12-10 Kai Feng , Han Hong , Ke Tang , Jingyuan Wang

The receiver operating characteristic (ROC) curve is a very useful tool for analyzing the diagnostic/classification power of instruments/classification schemes as long as a binary-scale gold standard is available. When the gold standard is…

Methodology · Statistics 2011-05-10 Zhanfeng Wang , Yuan-chin Ivan Chang
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