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The Receiver Operating Characteristic (ROC) surface is a generalization of ROC curve and is widely used for assessment of the accuracy of diagnostic tests on three categories. A complication called the verification bias, meaning that not…

Applications · Statistics 2018-03-20 Rui Zhu , Subhashis Ghosal

Artificial intelligence (AI)-based methods are showing promise in multiple medical-imaging applications. Thus, there is substantial interest in clinical translation of these methods, requiring in turn, that they be evaluated rigorously. In…

Paired comparison models are used for analyzing data that involves pairwise comparisons among a set of objects. When the outcomes of the pairwise comparisons have no ties, the paired comparison models can be generalized as a class of binary…

Methodology · Statistics 2022-11-29 Ran Huo , Mark E. Glickman

Can we teach machines to assess the expertise of humans solving visual tasks automatically based on eye tracking features? This paper proposes AutoSIGHT, Automatic System for Immediate Grading of Human experTise, that classifies expert and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Byron Dowling , Jozef Probcin , Adam Czajka

Receiver operating characteristic (ROC) curves are used ubiquitously to evaluate covariates, markers, or features as potential predictors in binary problems. We distinguish raw ROC diagnostics and ROC curves, elucidate the special role of…

Methodology · Statistics 2018-09-14 Tilmann Gneiting , Peter Vogel

In this paper, we propose a mean score equation-based approach to estimate the the volume under the receiving operating characteristic (ROC) surface (VUS) of a diagnostic test, under nonignorable (NI) verification bias. The proposed…

Methodology · Statistics 2019-06-21 Duc-Khanh To , Gianfranco Adimari , Monica Chiogna

Classification is a common statistical task in many areas. In order to ameliorate the performance of the existing methods, there are always some new classification procedures proposed. These procedures, especially those raised in the…

Methodology · Statistics 2026-05-05 Yuan-chin Ivan Chang

Comprehensive and accurate evaluation of general-purpose AI systems such as large language models allows for effective mitigation of their risks and deepened understanding of their capabilities. Current evaluation methodology, mostly based…

Artificial Intelligence · Computer Science 2024-01-01 Xiting Wang , Liming Jiang , Jose Hernandez-Orallo , David Stillwell , Luning Sun , Fang Luo , Xing Xie

Dental panoramic radiographs (DPRs) are widely used in clinical practice for comprehensive oral assessment but present challenges due to overlapping structures and time constraints in interpretation. This study aimed to establish a solid…

ROC analyses are considered under a variety of assumptions concerning the distributions of a measurement $X$ in two populations. These include the binormal model as well as nonparametric models where little is assumed about the form of…

Applications · Statistics 2021-03-02 Luai Al Labadi , Michael Evans , Qiaoyu Liang

Research on decision support applications in healthcare, such as those related to diagnosis, prediction, treatment planning, etc., have seen enormously increased interest recently. This development is thanks to the increase in data…

Machine Learning · Computer Science 2021-03-25 Jussi Tohka , Mark van Gils

Recent progress in Medical Artificial Intelligence (AI) has delivered systems that can reach clinical expert level performance. However, such systems tend to demonstrate sub-optimal "out-of-distribution" performance when evaluated in…

In diagnostic studies, researchers frequently encounter imperfect reference standards with some misclassified labels. Treating these as gold standards can bias receiver operating characteristic (ROC) curve analysis. To address this issue,…

Methodology · Statistics 2025-02-13 Yifan Sun , Peijun Sang , Qinglong Tian , Pengfei Li

The receiver operating characteristic (ROC) curve is an important graphic tool for evaluating a test in a wide range of disciplines. While useful, an ROC curve can cross the chance line, either by having an S-shape or a hook at the extreme…

Methodology · Statistics 2024-07-02 Soutik Ghosal , Zhen Chen

Area Under the Receiver Operating Characteristic Curve (AUC-ROC) is a popular evaluation metric for binary classifiers. In this paper, we discuss techniques to segment the AUC-ROC along human-interpretable dimensions. AUC-ROC is not an…

Machine Learning · Computer Science 2022-05-25 Arya Tafvizi , Besim Avci , Mukund Sundararajan

Classification performance is often not uniform over the data. Some areas in the input space are easier to classify than others. Features that hold information about the "difficulty" of the data may be non-discriminative and are therefore…

Machine Learning · Computer Science 2016-05-24 Oran Richman , Shie Mannor

Artificial intelligence (AI) systems increasingly match or surpass human experts in biomedical signal interpretation. However, their effective integration into clinical practice requires more than high predictive accuracy. Clinicians must…

Machine Learning · Computer Science 2025-10-27 Stefan Kraft , Andreas Theissler , Vera Wienhausen-Wilke , Gjergji Kasneci , Hendrik Lensch

For safety, medical AI systems undergo thorough evaluations before deployment, validating their predictions against a ground truth which is assumed to be fixed and certain. However, this ground truth is often curated in the form of…

The comparison of Receiver Operating Characteristic (ROC) curves is frequently used in the literature to compare the discriminatory capability of different classification procedures based on diagnostic variables. The performance of these…

Several efforts have been done to bring ROC analysis beyond (binary) classification, especially in regression. However, the mapping and possibilities of these proposals do not correspond to what we expect from the analysis of operating…

Statistics Theory · Mathematics 2013-10-17 Jose Hernandez-Orallo