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Alzheimer's disease is a degenerative brain disease. Being the primary cause of Dementia in adults and progressively destroys brain memory. Though Alzheimer's disease does not have a cure currently, diagnosing it at an earlier stage will…

Machine Learning · Computer Science 2023-02-17 Shrish Pellakur , Nelly Elsayed , Zag ElSayed , Murat Ozer

Predicting brain maturity using noninvasive magnetic resonance images (MRI) can distinguish different age groups and help to assess neurodevelopmental disorders. However, group-wise differences are often less informative for assessing…

Neurons and Cognition · Quantitative Biology 2014-12-17 Cheol E. Han , Luis R. Peraza , John-Paul Taylor , Marcus Kaiser

Deep Learning (DL) in neuroimaging has become increasingly relevant for detecting neurological conditions and neurodegenerative disorders. One of the most predominant biomarkers in neuroimaging is represented by brain age, which has been…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Carlo Alberto Barbano , Matteo Brunello , Benoit Dufumier , Marco Grangetto

Brain age prediction based on neuroimaging data could help characterize both the typical brain development and neuropsychiatric disorders. Pattern recognition models built upon functional connectivity (FC) measures derived from resting…

Computer Vision and Pattern Recognition · Computer Science 2018-01-15 Hongming Li , Theodore D. Satterthwaite , Yong Fan

Understanding how decision making changes across the lifespan is a central challenge for neuroscience, yet research on cognitive aging has remained largely disconnected from the theoretical and computational advances that now shape modern…

Neurons and Cognition · Quantitative Biology 2026-03-04 Michael B. Ryan , Letizia Ye , Anne K. Churchland

Brain aging trajectories differ between males and females, yet the genetic factors underlying these differences remain underexplored. Using structural MRI and genotyping data from 40,940 UK Biobank participants (aged 45-83), we computed…

Skeletal bone age assessment (BAA), as an essential imaging examination, aims at evaluating the biological and structural maturation of human bones. In the clinical practice, Tanner and Whitehouse (TW2) method is a widely-used method for…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Dong Wang , Kexin Zhang , Jia Ding , Liwei Wang

Automatic identification and categorization of Alzheimer's patients and the ability to distinguish between different levels of this disease can be very helpful to the research community in this field, since other non-automatic approaches…

Signal Processing · Electrical Eng. & Systems 2019-04-17 Esmaeil Seraj , Mehran Yazdi , Nastaran Shahparian

Age prediction is an important part of medical assessments and research. It can aid in detecting diseases as well as abnormal ageing by highlighting potential discrepancies between chronological and biological age. To improve understanding…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Sophie Starck , Yadunandan Vivekanand Kini , Jessica Johanna Maria Ritter , Rickmer Braren , Daniel Rueckert , Tamara Mueller

Background: Regarding the importance of right diagnosis in medical applications, various methods have been exploited for processing medical images solar. The method of segmentation is used to analyze anal to miscall structures in medical…

Image and Video Processing · Electrical Eng. & Systems 2019-07-24 Amir Javadpour , Alireza Mohammadi

Medical image segmentation can provide a reliable basis for further clinical analysis and disease diagnosis. The performance of medical image segmentation has been significantly advanced with the convolutional neural networks (CNNs).…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Ruxin Wang , Shuyuan Chen , Chaojie Ji , Jianping Fan , Ye Li

The process of integration of inputs from several sensory modalities in the human brain is referred to as multisensory integration. Age-related cognitive decline leads to a loss in the ability of the brain to conceive multisensory inputs.…

Signal Processing · Electrical Eng. & Systems 2023-05-02 Prerna Singh , Ayush Tripathi , Lalan Kumar , Tapan Kumar Gandhi

In human face-based biometrics, gender classification and age estimation are two typical learning tasks. Although a variety of approaches have been proposed to handle them, just a few of them are solved jointly, even so, these joint methods…

Computer Vision and Pattern Recognition · Computer Science 2016-09-15 Qing Tian , Songcan Chen

While utilizing machine learning models, one of the most crucial aspects is how bias and fairness affect model outcomes for diverse demographics. This becomes especially relevant in the context of machine learning for medical imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-10-19 Mahsa Dibaji , Neha Gianchandani , Akhil Nair , Mansi Singhal , Roberto Souza , Mariana Bento

Imaging findings inconsistent with those expected at specific chronological age ranges may serve as early indicators of neurological disorders and increased mortality risk. Estimation of chronological age, and deviations from expected…

Computer vision researchers prefer to estimate age from face images because facial features provide useful information. However, estimating age from face images becomes challenging when people are distant from the camera or occluded. A…

Computer Vision and Pattern Recognition · Computer Science 2020-02-03 Haiping Zhu , Yuheng Zhang , Guohao Li , Junping Zhang , Hongming Shan

Brain network topology, derived from functional magnetic resonance imaging (fMRI), holds promise for improving Alzheimer's disease (AD) diagnosis. Current methods primarily focus on lower-order topological features, often overlooking the…

Geometric Topology · Mathematics 2025-09-19 Dengyi Zhao , Shanyong Li , Yunping Wang , Chenfei Wang , Zhiheng Zhou , Guiying Yan , Xingqin Qi

Machine learning (ML) has shown great promise for revolutionizing a number of areas, including healthcare. However, it is also facing a reproducibility crisis, especially in medicine. ML models that are carefully constructed from and…

Machine Learning · Computer Science 2024-09-16 Rongguang Wang , Guray Erus , Pratik Chaudhari , Christos Davatzikos

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory and cognitive decline, affecting millions worldwide. Diagnosing AD is challenging due to its heterogeneous nature and variable progression. This…

Neurons and Cognition · Quantitative Biology 2024-10-22 Jiwon Youn , Dong Woo Kang , Hyun Kook Lim , Mansu Kim

Spontaneous brain activity generically displays transient spatiotemporal coherent structures, which can selectively be affected in various neurological and psychiatric pathologies. Here we model the full brain's electroencephalographic…

Neurons and Cognition · Quantitative Biology 2025-02-25 Annalisa Caligiuri , David Papo , Görsev Yener , Bahar Güntekin , Tobias Galla , Lucas Lacasa , Massimiliano Zanin