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Magnetic Resonance Imaging (MRI) of the fetal brain has become a key tool for studying brain development in vivo. Yet, its assessment remains challenging due to variability in brain maturation, imaging protocols, and uncertain estimates of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Johannes Tischer , Patric Kienast , Marlene Stümpflen , Gregor Kasprian , Georg Langs , Roxane Licandro

We present a novel method for quantifying the microscopic structure of brain tissue. It is based on the automated recognition of interpretable features obtained by analyzing the shapes of cells. This contrasts with prevailing methods of…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Kui Qian , Litao Qiao , Beth Friedman , Edward O'Donnell , David Kleinfeld , Yoav Freund

Planning of radiotherapy involves accurate segmentation of a large number of organs at risk, i.e. organs for which irradiation doses should be minimized to avoid important side effects of the therapy. We propose a deep learning method for…

Image and Video Processing · Electrical Eng. & Systems 2019-07-04 Pawel Mlynarski , Hervé Delingette , Hamza Alghamdi , Pierre-Yves Bondiau , Nicholas Ayache

Given the wide success of convolutional neural networks (CNNs) applied to natural images, researchers have begun to apply them to neuroimaging data. To date, however, exploration of novel CNN architectures tailored to neuroimaging data has…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Pascal Sturmfels , Saige Rutherford , Mike Angstadt , Mark Peterson , Chandra Sripada , Jenna Wiens

Predicting an individual's aging trajectory is a central challenge in preventative medicine and bioinformatics. While machine learning models can predict chronological age from biomarkers, they often fail to capture the dynamic,…

Machine Learning · Computer Science 2025-08-14 Nazira Dunbayeva , Yulong Li , Yutong Xie , Imran Razzak

Face aging is the task aiming to translate the faces in input images to designated ages. To simplify the problem, previous methods have limited themselves only able to produce discrete age groups, each of which consists of ten years.…

Computer Vision and Pattern Recognition · Computer Science 2021-03-01 Seogkyu Jeon , Pilhyeon Lee , Kibeom Hong , Hyeran Byun

Convolutional Neural Networks play a key role in bone age assessment for investigating endocrinology, genetic, and growth disorders under various modalities and body regions. However, no researcher has tackled bone age…

Image and Video Processing · Electrical Eng. & Systems 2021-10-19 Shinji Nakazawa , Changhee Han , Joe Hasei , Ryuichi Nakahara , Toshifumi Ozaki

Naked eye recognition of age is usually based on comparison with the age of others. However, this idea is ignored by computer tasks because it is difficult to obtain representative contrast images of each age. Inspired by the transfer…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Ping Chen , Xingpeng Zhang , Ye Li , Ju Tao , Bin Xiao , Bing Wang , Zongjie Jiang

In this paper authors present a general methodology for age dependent reliability analysis of degrading or ageing systems, structures and components.The methodology is based on Bayesian methods and inference, its ability to incorporate…

Applications · Statistics 2012-10-19 Robertas Alzbutas , Tomas Iešmantas

Early and accurate detection of Alzheimer's disease (AD) remains a major challenge in medical diagnosis due to its subtle onset and progressive nature. This research introduces an explainable ensemble learning Framework designed to classify…

Machine Learning · Computer Science 2026-03-06 Nishan Mitra

Feature attribution (FA), or the assignment of class-relevance to different locations in an image, is important for many classification problems but is particularly crucial within the neuroscience domain, where accurate mechanistic models…

Machine Learning · Computer Science 2020-06-17 Cher Bass , Mariana da Silva , Carole Sudre , Petru-Daniel Tudosiu , Stephen M. Smith , Emma C. Robinson

Background: While deep learning technology, which has the capability of obtaining latent representations based on large-scale data, can be a potential solution for the discovery of a novel aging biomarker, existing deep learning methods for…

Machine Learning · Computer Science 2023-02-02 Seong-Eun Moon , Ji Won Yoon , Shinyoung Joo , Yoohyung Kim , Jae Hyun Bae , Seokho Yoon , Haanju Yoo , Young Min Cho

Age estimation is an essential challenge in computer vision. With the advances of convolutional neural networks, the performance of age estimation has been dramatically improved. Existing approaches usually treat age estimation as a…

Computer Vision and Pattern Recognition · Computer Science 2021-06-18 Yi Zhou , Heikki Huttunen , Tapio Elomaa

Alzheimer's Disease (AD) is characterized by a cascade of biomarkers becoming abnormal, the pathophysiology of which is very complex and largely unknown. Event-based modeling (EBM) is a data-driven technique to estimate the sequence in…

Machine Learning · Computer Science 2019-08-14 Vikram Venkatraghavan , Esther E. Bron , Wiro J. Niessen , Stefan Klein

The human face contains important and understandable information such as personal identity, gender, age, and ethnicity. In recent years, a person's age has been studied as one of the important features of the face. The age estimation system…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Mahtab Taheri , Mahdi Taheri , Amirhossein Hadjahmadi

Purpose: This study investigates whether a machine-learning-based system can predict the rate of cognitive decline in mildly cognitively impaired patients by processing only the clinical and imaging data collected at the initial visit.…

Quantitative Methods · Quantitative Biology 2020-10-07 Sema Candemir , Xuan V. Nguyen , Luciano M. Prevedello , Matthew T. Bigelow , Richard D. White , Barbaros S. Erdal

Objective Brain Age Index (BAI), calculated from sleep electroencephalography (EEG), has been proposed as a biomarker of brain health. This study quantifies night-to-night variability of BAI and establishes probability thresholds for…

Integrating brain imaging data with clinical reports offers a valuable opportunity to leverage complementary multimodal information for more effective and timely diagnosis in practical clinical settings. This approach has gained significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Jing Zhang , Xiaowei Yu , Minheng Chen , Lu Zhang , Tong Chen , Yan Zhuang , Chao Cao , Yanjun Lyu , Li Su , Tianming Liu , Dajiang Zhu

Imaging and genomic data offer distinct and rich features, and their integration can unveil new insights into the complex landscape of diseases. In this study, we present a novel approach utilizing radiogenomic data including structural MRI…

Machine Learning · Computer Science 2025-05-16 Aditya Raj , Golrokh Mirzaei

As the number of dementia patients rises, the need for accurate diagnostic procedures rises as well. Current methods, like using an MRI scan, rely on human input, which can be inaccurate. However, the decision logic behind machine learning…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Tyler Morris , Ziming Liu , Longjian Liu , Xiaopeng Zhao
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