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The rapid advance of DNA sequencing technologies has yielded databases of thousands of genomes. To search and index these databases effectively, it is important that we take advantage of the similarity between those genomes. Several authors…

Data Structures and Algorithms · Computer Science 2014-12-05 Travis Gagie , Simon J. Puglisi

Exact string matching has been a fundamental problem in computer science for decades because of many practical applications. Some are related to common procedures, such as searching in files and text editors, or, more recently, to more…

Data Structures and Algorithms · Computer Science 2019-07-29 Konstantinos F. Xylogiannopoulos

In this paper, we present an efficient deep learning based approach to extract technology-related topics and keywords within scientific literature, and identify corresponding technologies within patent applications. Specifically, we utilize…

Digital Libraries · Computer Science 2022-05-23 Daniel Hain , Roman Jurowetzki , Mariagrazia Squicciarini

We consider the problem of efficiently designing sets (codes) of equal-length DNA strings (words) that satisfy certain combinatorial constraints. This problem has numerous motivations including DNA computing and DNA self-assembly. Previous…

Data Structures and Algorithms · Computer Science 2007-05-23 Ming-Yang Kao , Manan Sanghi , Robert Schweller

Most existing algorithms for dictionary learning assume that all entries of the (high-dimensional) input data are fully observed. However, in several practical applications (such as hyper-spectral imaging or blood glucose monitoring), only…

Machine Learning · Statistics 2018-04-26 Thanh V. Nguyen , Akshay Soni , Chinmay Hegde

We now need more than ever to make genome analysis more intelligent. We need to read, analyze, and interpret our genomes not only quickly, but also accurately and efficiently enough to scale the analysis to population level. There currently…

This work presents a new approach for classification of genomic sequences from measurements of complex networks and information theory. For this, it is considered the nucleotides, dinucleotides and trinucleotides of a genomic sequence. For…

Computational Engineering, Finance, and Science · Computer Science 2014-12-19 Bruno Mendes Moro Conque , André Yoshiaki Kashiwabara , Fabrício Martins Lopes

We discuss a model of genome as a program with functional architecture and consider the approach to Darwinian evolution as a learning problem for functional programming. In particular we introduce a model of learning for some class of…

Neural and Evolutionary Computing · Computer Science 2020-06-18 S. V. Kozyrev

We present {\em generative clustering} (GC) for clustering a set of documents, $\mathrm{X}$, by using texts $\mathrm{Y}$ generated by large language models (LLMs) instead of by clustering the original documents $\mathrm{X}$. Because LLMs…

Machine Learning · Computer Science 2024-12-19 Xin Du , Kumiko Tanaka-Ishii

One of the defining features of living systems is their adaptability to changing environmental conditions. This requires organisms to extract temporal and spatial features of their environment, and use that information to compute the…

Neurons and Cognition · Quantitative Biology 2024-02-27 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

Understanding the complexity of human language requires an appropriate analysis of the statistical distribution of words in texts. We consider the information retrieval problem of detecting and ranking the relevant words of a text by means…

Computation and Language · Computer Science 2008-06-07 Juan P. Herrera , Pedro A. Pury

A systematic review identifies and collates various clinical studies and compares data elements and results in order to provide an evidence based answer for a particular clinical question. The process is manual and involves lot of time. A…

Information Retrieval · Computer Science 2016-06-22 Tanmay Basu , Shraman Kumar , Abhishek Kalyan , Priyanka Jayaswal , Pawan Goyal , Stephen Pettifer , Siddhartha R. Jonnalagadda

The SemanticWeb emerged as an extension to the traditional Web, towards adding meaning to a distributed Web of structured and linked data. At its core, the concept of ontology provides the means to semantically describe and structure…

Artificial Intelligence · Computer Science 2021-05-03 Konstantinos Sikelis , George E Tsekouras , Konstantinos I Kotis

We propose that the distribution of DNA words in genomic sequences can be primarily characterized by a double Pareto-lognormal distribution, which explains lognormal and power-law features found across all known genomes. Such a distribution…

Genomics · Quantitative Biology 2007-05-23 Miklós Csűrös , Laurent Noé , Gregory Kucherov

Performing effective preference-based data retrieval requires detailed and preferentially meaningful structurized information about the current user as well as the items under consideration. A common problem is that representations of items…

Artificial Intelligence · Computer Science 2011-01-13 Joachim Selke , Wolf-Tilo Balke

The avalanche quantity of the information developed by mankind has led to concept of automation of knowledge extraction - Data Mining ([1]). This direction is connected with a wide spectrum of problems - from recognition of the fuzzy set to…

Machine Learning · Computer Science 2009-06-05 A. A. Shumeyko , S. L. Sotnik

Genomic and metagenomic fields, generating huge sets of short genomic sequences, brought their own share of high performance problems. To extract relevant pieces of information from the huge data sets generated by current sequencing…

Data Structures and Algorithms · Computer Science 2016-05-27 Camille Marchet , Antoine Limasset , Lucie Bittner , Pierre Peterlongo

Given a sequence composed of a limit number of characters, we try to "read" it as a "text". This involves to segment the sequence into "words". The difficulty is to distinguish good segmentation from enormous number of random ones.Aiming at…

Biological Physics · Physics 2009-11-06 Bin Wang

With the proliferation of research means and computational methodologies, published biomedical literature is growing exponentially in numbers and volume. Cancer cell lines are frequently used models in biological and medical research that…

Computation and Language · Computer Science 2024-02-13 Ellery Smith , Rahel Paloots , Dimitris Giagkos , Michael Baudis , Kurt Stockinger

Genetic algorithms are heuristic optimization techniques inspired by Darwinian evolution, which are characterized by successfully finding robust solutions for optimization problems. Here, we propose a subroutine-based quantum genetic…

Quantum Physics · Physics 2024-06-07 Rubén Ibarrondo , Giancarlo Gatti , Mikel Sanz
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