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We introduce HAMscope, a compact, snapshot hyperspectral autofluorescence miniscope that enables real-time, label-free molecular imaging in a wide range of biological systems. By integrating a thin polymer diffuser into a widefield…

To synthesize diffusion MR measurements from Monte-Carlo simulation using tissue models with sizes comparable to those of scan voxels. Larger regions enable restricting structures to be modeled in greater detail and improve accuracy and…

Computational Physics · Physics 2017-01-16 Matt G Hall , Gemma Nedjati-Gilani , Daniel C Alexander

This is the first article in a series of three dealing with the exploitation of speckle for imaging purposes. Speckle is the complex interference wave-field produced by a random distribution of un-resolved scatterers. In this paper, we show…

Applied Physics · Physics 2026-02-06 Elsa Giraudat , Flavien Bureau , William Lambert , Mathias Fink , Alexandre Aubry

We report a light-field based method that allows the optical encryption of three-dimensional (3D) volumetric information at the microscopic scale in a single 2D light-field image. The system consists of a microlens array and an array of…

Cryptography and Security · Computer Science 2016-10-28 Haoyu Li , Changliang Guo , Inbarasan Muniraj , Bryce C. Schroeder , John T. Sheridan , Shu Jia

Apart from a lot of fundamental interest, vector Bessel beams are widely used in optical manipulation, material processing, and imaging. However, the existing description of such beams remains fragmentary, especially when their scattering…

Optics · Physics 2022-09-15 Stefania A. Glukhova , Maxim A. Yurkin

We present a comprehensive methodology for the simulation of astronomical images from optical survey telescopes. We use a photon Monte Carlo approach to construct images by sampling photons from models of astronomical source populations,…

Stimulated Raman scattering (SRS) microscopy has emerged as a powerful technique for probing the spatiotemporal dynamics of molecular bonds with exceptional sensitivity, resolution, and speed. However, classically, its performance remains…

In this report, we demonstrate a new principle to improve the resolution of the acoustic microscopy, which is based on the sub-wavelength focusing of acoustic wave passing through an acoustically transparent mesoscale particle. In the…

General Physics · Physics 2017-12-06 I. V. Minin , Q. Tang , S. Bhuyan , J. Hu , O. V. Minin

This paper describes the architecture and demonstrates the capabilities of a newly developed, physically-based imaging simulator environment called SISPO, developed for small solar system body fly-by and terrestrial planet surface mission…

We present the 'simage' software suite for the simulation of artificial extragalactic images, based empirically around real observations of the Hubble Ultra Deep Field (UDF). The simulations reproduce galaxies with realistic and complex…

Instrumentation and Methods for Astrophysics · Physics 2015-05-19 Benjamin M. Dobke , David E. Johnston , Richard Massey , F. William High , Matthew Ferry , Jason Rhodes , R. Ali Vanderveld

The near-field acoustic scattering from a sphere centered on the axis of a finite Bessel acoustic beam is derived stemming from the Rayleigh-Sommerfeld diffraction surface integral and the addition theorems for the spherical wave and…

Classical Physics · Physics 2020-07-21 F. G. Mitri

The efficient simulation of quantum systems is a primary motivating factor for developing controllable quantum machines. For addressing systems with underlying bosonic structure, it is advantageous to utilize a naturally bosonic platform.…

Bessel beams are non-diffracting light structures, which can be produced with simple tabletop optical elements such as axicon lenses or ring spatial filters and coherent laser beams. One of their main characteristic is that Bessel beams…

We introduce Perceval, an open-source software platform for simulating and interfacing with discrete-variable photonic quantum computers, and describe its main features and components. Its Python front-end allows photonic circuits to be…

Computational Cannula Microscopy (CCM) is a high-resolution widefield fluorescence imaging approach deep inside tissue, which is minimally invasive. Rather than using conventional lenses, a surgical cannula acts as a lightpipe for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ruipeng Guo , Zhimeng Pan , Andrew Taibi , Jason Shepherd , Rajesh Menon

High-content biological microscopy targets high-resolution imaging across large fields-of-view (FOVs). Recent works have demonstrated that computational imaging can provide efficient solutions for high-content microscopy. Here, we use…

Image and Video Processing · Electrical Eng. & Systems 2019-03-28 Li-Hao Yeh , Shwetadwip Chowdhury , Laura Waller

The efficient mixing of fluid samples in miniaturized total analysis systems is essential for numerous applications including biological screening assays, chemical extraction, polymerization, cell analysis, and protein folding. Miniaturized…

Fluid Dynamics · Physics 2022-10-25 S. A. Iqrar , J. Park , M. Afzal , H. J. Sung

We report a novel lensless on-chip microscopy platform based on near-field blind ptychographic modulation. In this platform, we place a thin diffuser in between the object and the image sensor for light wave modulation. By blindly scanning…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 Shaowei Jiang , Jiakai Zhu , Pengming Song , Chengfei Guo , Zichao Bian , Ruihai Wang , Yikun Huang , Shiyao Wang , He Zhang , Guoan Zheng

Photoacoustic (PA) imaging systems based on clinical linear ultrasound arrays have become increasingly popular in translational PA research. Such systems can be more easily integrated in a clinical workflow due to the simultaneous access to…

In this work we propose an efficient and accurate multi-scale optical simulation algorithm by applying a numerical version of slowly varying envelope approximation in FEM. Specifically, we employ the fast iterative method to quickly compute…

Optics · Physics 2024-12-03 Fan Xiao , Jingwei Wang , Zhongfei Xiong , Yuntian Chen