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High quality real world datasets are essential for advancing data driven approaches in type 1 diabetes (T1D) management, including personalized therapy design, digital twin systems, and glucose prediction models. However, progress in this…

Machine Learning · Computer Science 2025-06-19 Saman Khamesian , Asiful Arefeen , Bithika M. Thompson , Maria Adela Grando , Hassan Ghasemzadeh

Effective diabetes management relies heavily on the continuous monitoring of blood glucose levels, traditionally achieved through invasive and uncomfortable methods. While various non-invasive techniques have been explored, such as optical,…

Machine Learning · Computer Science 2024-08-16 Nihat Ahmadli , Mehmet Ali Sarsil , Onur Ergen

Every year, humanity loses about 1.5 million persons due to diabetic disease. Therefore continuous monitoring of diabetes is highly needed, but the conventional approach, i.e., fingertip pricking, causes mental and physical pain to the…

Signal Processing · Electrical Eng. & Systems 2024-11-19 Abdelrhman Y. Soliman , Ahmed M. Nor , Octavian Fratu , Simona Halunga , Osama A. Omer , Ahmed S. Mubark

Machine learning shows remarkable success for recognizing patterns in data. Here we apply the machine learning (ML) for the diagnosis of early stage diabetes, which is known as a challenging task in medicine. Blood glucose levels are…

Quantitative Methods · Quantitative Biology 2021-02-24 Woo Seok Lee , Junghyo Jo , Taegeun Song

Background: Clinical diagnosis is typically reached by following a series of steps recommended by guidelines authored by colleges of experts. Accordingly, guidelines play a crucial role in rationalizing clinical decisions but suffer from…

Machine Learning · Computer Science 2024-04-10 Lillian Muyama , Antoine Neuraz , Adrien Coulet

Background: Type 2 diabetes (T2D) is a prevalent chronic disease with a significant risk of serious health complications and negative impacts on the quality of life. Given the impact of individual characteristics and lifestyle on the…

Machine Learning · Computer Science 2024-01-08 Syed Hasib Akhter Faruqui , Adel Alaeddini , Yan Du , Shiyu Li , Kumar Sharma , Jing Wang

Accurate prediction of cardiovascular disease (CVD) risk is crucial for healthcare institutions. This study addresses the growing prevalence of diabetes and its strong link to heart disease by proposing an efficient CVD risk prediction…

Machine Learning · Computer Science 2025-11-10 Esha Chowdhury

Glycemic control is essential for critical care. However, it is a challenging task because there has been no study on personalized optimal strategies for glycemic control. This work aims to learn personalized optimal glycemic trajectories…

Machine Learning · Computer Science 2017-12-05 Wei-Hung Weng , Mingwu Gao , Ze He , Susu Yan , Peter Szolovits

Precise glucose level monitoring is critical for people with diabetes to avoid serious complications. While there are several methods for continuous glucose level monitoring, research on maintenance devices is limited. To mitigate the gap,…

Machine Learning · Computer Science 2024-06-10 Azmine Toushik Wasi

Clinical diagnostic guidelines outline the key questions to answer to reach a diagnosis. Inspired by guidelines, we aim to develop a model that learns from electronic health records to determine the optimal sequence of actions for accurate…

Large clinical evidence acknowledges the crucial role played by physical activity in delaying the progression of type-2 diabetes. However, the literature lacks control approaches that leverage exercise for type-2 diabetes control and more…

Systems and Control · Electrical Eng. & Systems 2025-01-23 Pierluigi Francesco De Paola , Alessandro Borri , Fabrizio Dabbene , Pasquale Palumbo , Alessia Paglialonga

Diabetes mellitus is a global health crisis characterized by poor blood sugar regulation, impacting millions of people worldwide and leading to severe complications and mortality. Although Type 1 Diabetes Mellitus (T1DM) has a lower number…

Other Quantitative Biology · Quantitative Biology 2025-04-14 Rinrada Jadsadaphongphaibool , Dadi Bi , Christian D. Lorenz , Yansha Deng , Robert Schober

This paper is a study of reinforcement learning (RL) as an optimal-control strategy for control of nonlinear valves. It is evaluated against the PID (proportional-integral-derivative) strategy, using a unified framework. RL is an autonomous…

Machine Learning · Computer Science 2021-02-05 Rajesh Siraskar

In this paper, we present a model free approach to calculate long-acting insulin doses for Type 2 Diabetic (T2D) subjects in order to bring their blood glucose (BG) concentration to be within a safe range. The proposed strategy tunes the…

Systems and Control · Electrical Eng. & Systems 2022-12-29 Mohamad Al Ahdab , Torben Knudsen , Jakob Stoustrup , John Leth

Research in diabetes, especially when it comes to building data-driven models to forecast future glucose values, is hindered by the sensitive nature of the data. Because researchers do not share the same data between studies, progress is…

Quantitative Methods · Quantitative Biology 2020-09-10 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

Diabetes cases worldwide have risen steadily over the past decades, lending urgency to the search for more efficient, effective, and personalized ways to treat the disease. Current treatment strategies, however, may fail to maintain…

Tissues and Organs · Quantitative Biology 2014-03-05 S. M. Kissler , C. Cichowitz , S. Sankaranarayanan , D. M. Bortz

Reinforcement learning (RL) is a type of artificial intelligence for making optimal choices. In healthcare, researchers generally use offline RL (ORL), where models are trained and evaluated from retrospective observational data. To…

Machine Learning · Computer Science 2026-04-30 Thomas Frost , Hrisheekesh Vaidya , Steve Harris

Deep reinforcement learning (DRL) is a machine learning-based method suited for complex and high-dimensional control problems. In this study, a real-time control system based on DRL is developed for long-term voltage stability events. The…

Systems and Control · Electrical Eng. & Systems 2022-07-12 Hannes Hagmar , Le Anh Tuan , Robert Eriksson

People with diabetes have to manage their blood glucose level to keep it within an appropriate range. Predicting whether future glucose values will be outside the healthy threshold is of vital importance in order to take corrective actions…

Machine Learning · Computer Science 2023-04-03 J. Alvarado , J. Manuel Velasco , F. Chávez , J. Ignacio Hidalgo , F. Fernández de Vega

Reinforcement Learning (RL) can be used to fit a mapping from patient state to a medication regimen. Prior studies have used deterministic and value-based tabular learning to learn a propofol dose from an observed anesthetic state. Deep RL…

Machine Learning · Computer Science 2020-09-10 Gabe Schamberg , Marcus Badgeley , Emery N. Brown