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Osteosarcoma is the most common primary malignant bone tumor, which has high mortality due to easy lung metastasis. Osteosarcoma is a highly anaplastic, pleomorphic tumor with a variety of tumor cell morphology, including fusiform, oval,…

Medical Physics · Physics 2021-01-27 Yu Fu

Brain tumor segmentation is one of the most challenging problems in medical image analysis. The goal of brain tumor segmentation is to generate accurate delineation of brain tumor regions. In recent years, deep learning methods have shown…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Zhihua Liu , Lei Tong , Zheheng Jiang , Long Chen , Feixiang Zhou , Qianni Zhang , Xiangrong Zhang , Yaochu Jin , Huiyu Zhou

Recently, segmentation methods based on Convolutional Neural Networks (CNNs) showed promising performance in automatic Multiple Sclerosis (MS) lesions segmentation. These techniques have even outperformed human experts in controlled…

Image and Video Processing · Electrical Eng. & Systems 2021-07-26 Reda Abdellah Kamraoui , Vinh-Thong Ta , Thomas Tourdias , Boris Mansencal , José V Manjon , Pierrick Coupé

Neuroblastoma is a strongly heterogeneous cancer with very diverse clinical courses that may vary from spontaneous regression to fatal progression; an accurate patient's risk estimation at diagnosis is essential to design appropriate tumor…

Quantitative Methods · Quantitative Biology 2018-02-23 Valerio Maggio , Marco Chierici , Giuseppe Jurman , Cesare Furlanello

This paper provides a critical review of the literature on deep learning applications in breast tumor diagnosis using ultrasound and mammography images. It also summarizes recent advances in computer-aided diagnosis (CAD) systems, which…

Image and Video Processing · Electrical Eng. & Systems 2020-10-05 Yuliana Jiménez-Gaona , María José Rodríguez-Álvarez , Vasudevan Lakshminarayanan

The isocitrate dehydrogenase (IDH) gene mutation status is an important biomarker for glioma patients. The gold standard of IDH mutation detection requires tumour tissue obtained via invasive approaches and is usually expensive. Recent…

Machine Learning · Computer Science 2022-01-17 Yiran Wei , Chao Li , Xi Chen , Carola-Bibiane Schönlieb , Stephen J. Price

Lung cancer has a high rate of recurrence in early-stage patients. Predicting the post-surgical recurrence in lung cancer patients has traditionally been approached using single modality information of genomics or radiology images. We…

Image and Video Processing · Electrical Eng. & Systems 2020-02-07 Vaishnavi Subramanian , Minh N. Do , Tanveer Syeda-Mahmood

Glioma is one of the most common and aggressive types of primary brain tumors. The accurate segmentation of subcortical brain structures is crucial to the study of gliomas in that it helps the monitoring of the progression of gliomas and…

Image and Video Processing · Electrical Eng. & Systems 2018-03-02 Lele Chen , Yue Wu , Adora M. DSouza , Anas Z. Abidin , Axel Wismuller , Chenliang Xu

Detecting cancers at early stages can dramatically reduce mortality rates. Therefore, practical cancer screening at the population level is needed. Here, we develop a comprehensive detection system to classify all common cancer types. By…

Molecular Networks · Quantitative Biology 2021-03-30 Anyou Wang , Rong Hai , Paul J Rider , Qianchuan He

T2-weighted magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) are essential components for cervical cancer diagnosis. However, combining these channels for training deep learning models are challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Reza Kalantar , Sebastian Curcean , Jessica M Winfield , Gigin Lin , Christina Messiou , Matthew D Blackledge , Dow-Mu Koh

Existing approaches to modeling the dynamics of brain tumor growth, specifically glioma, employ biologically inspired models of cell diffusion, using image data to estimate the associated parameters. In this work, we propose an alternative…

Objectives: Glioblastomas are the most aggressive brain and central nervous system (CNS) tumors with poor prognosis in adults. The purpose of this study is to develop a machine-learning based classification method using radio-mic features…

Medical Physics · Physics 2019-11-25 Ge Cui , Jiwoong Jeong , Bob Press , Yang Lei , Hui-Kuo Shu , Tian Liu , Walter Curran , Hui Mao , Xiaofeng Yang

A new paradigm is beginning to emerge in Radiology with the advent of increased computational capabilities and algorithms. This has led to the ability of real time learning by computer systems of different lesion types to help the…

Lung cancer is a leading cause of cancer mortality globally, highlighting the importance of understanding its mortality risks to design effective patient-centered therapies. The National Lung Screening Trial (NLST) employed computed…

The interactions between tumor cells and the tumor microenvironment (TME) dictate therapeutic efficacy of radiation and many systemic therapies in breast cancer. However, to date, there is not a widely available method to reproducibly…

Hypoxia occurs when tumour cells outgrow their blood supply, leading to regions of low oxygen levels within the tumour. Calculating hypoxia levels can be an important step in understanding the biology of tumours, their clinical progression…

Computer Vision and Pattern Recognition · Computer Science 2023-11-22 Petru Manescu , Joseph Geradts , Delmiro Fernandez-Reyes

Spiculations/lobulations, sharp/curved spikes on the surface of lung nodules, are good predictors of lung cancer malignancy and hence, are routinely assessed and reported by radiologists as part of the standardized Lung-RADS clinical…

Image and Video Processing · Electrical Eng. & Systems 2022-07-01 Wookjin Choi , Navdeep Dahiya , Saad Nadeem

Melanoma is a fatal skin cancer that is curable and has dramatically increasing survival rate when diagnosed at early stages. Learning-based methods hold significant promise for the detection of melanoma from dermoscopic images. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Saban Ozturk , Tolga Cukur

Purpose: We aimed to develop deep machine learning (DL) models to improve the detection and segmentation of intraprostatic lesions (IL) on bp-MRI by using whole amount prostatectomy specimen-based delineations. We also aimed to investigate…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Zhenzhen Dai , Ivan Jambor , Pekka Taimen , Milan Pantelic , Mohamed Elshaikh , Craig Rogers , Otto Ettala , Peter Boström , Hannu Aronen , Harri Merisaari , Ning Wen

Brain tumor detection can make the difference between life and death. Recently, deep learning-based brain tumor detection techniques have gained attention due to their higher performance. However, obtaining the expected performance of such…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Wessam M. Salama , Ahmed Shokry