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Related papers: Optimal Sepsis Patient Treatment using Human-in-th…

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Under-resourced or rural hospitals have limited access to medical specialists and healthcare professionals, which can negatively impact patient outcomes in sepsis. To address this gap, we developed the MATEC (Multi-AI Agent Team Care)…

Human-Computer Interaction · Computer Science 2025-03-24 Andrew Cho , Jason M. Woo , Brian Shi , Aishwaryaa Udeshi , Jonathan S. H. Woo

For severely affected COVID-19 patients, it is crucial to identify high-risk patients and predict survival and need for intensive care (ICU). Most of the proposed models are not well reported making them less reproducible and prone to high…

Machine Learning · Computer Science 2024-03-29 Mahbubunnabi Tamala , Mohammad Marufur Rahmanb , Maryam Alhasimc , Mobarak Al Mulhimd , Mohamed Derichee

The progression of complex human diseases is associated with critical transitions across dynamical regimes. These transitions often spawn early-warning signals and provide insights into the underlying disease-driving mechanisms. In this…

Quantitative Methods · Quantitative Biology 2019-10-24 Pejman F. Ghalati , Satya S. Samal , Jayesh S. Bhat , Robert Deisz , Gernot Marx , Andreas Schuppert

Heart disease remains the leading cause of death in the United States. Compared with risk assessment guidelines that require manual calculation of scores, machine learning-based prediction for disease outcomes such as mortality can be…

Machine Learning · Computer Science 2018-12-13 Laura A. Barrett , Seyedeh Neelufar Payrovnaziri , Jiang Bian , Zhe He

AI tools increasingly guide targeted interventions in healthcare, education, and recruiting. Algorithms score individuals, trigger outreach to those above a threshold (e.g., high-risk or high-value), and encourage them to request service;…

Methodology · Statistics 2026-04-17 Carri W. Chan , Yi Han , Hannah Li , Benjamin L. Ranard

Sepsis is a life-threatening host response to infection associated with high mortality, morbidity, and health costs. Its management is highly time-sensitive since each hour of delayed treatment increases mortality due to irreversible organ…

Machine Learning · Computer Science 2020-10-16 Michael Moor , Max Horn , Bastian Rieck , Damian Roqueiro , Karsten Borgwardt

Artificial intelligence holds strong potential to support clinical decision making in intensive care units where timely and accurate risk assessment is critical. However, many existing models focus on isolated outcomes or limited data…

Objective: Sepsis is one of the most serious hospital conditions associated with high mortality. Sepsis is the result of a dysregulated immune response to infection that can lead to multiple organ dysfunction and death. Due to the wide…

Sepsis poses a major global health threat, accounting for millions of deaths annually and significant economic costs. Accurately predicting the risk of mortality in sepsis patients enables early identification, promotes the efficient…

Applications · Statistics 2024-11-11 Fanglin Dong

Glycemic control is essential for critical care. However, it is a challenging task because there has been no study on personalized optimal strategies for glycemic control. This work aims to learn personalized optimal glycemic trajectories…

Machine Learning · Computer Science 2017-12-05 Wei-Hung Weng , Mingwu Gao , Ze He , Susu Yan , Peter Szolovits

Postoperative stroke remains a critical complication in elderly surgical intensive care unit (SICU) patients, contributing to prolonged hospitalization, elevated healthcare costs, and increased mortality. Accurate early risk stratification…

Quantitative Methods · Quantitative Biology 2025-06-05 Tinghuan Li , Shuheng Chen , Junyi Fan , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Continuous diagnosis and prognosis are essential for intensive care patients. It can provide more opportunities for timely treatment and rational resource allocation, especially for sepsis, a main cause of death in ICU, and COVID-19, a new…

Machine Learning · Computer Science 2022-10-07 Chenxi Sun , Hongyan Li , Moxian Song , Derun Cai , Baofeng Zhang , Shenda Hong

Sepsis, a life-threatening condition triggered by the body's exaggerated response to infection, demands urgent intervention to prevent severe complications. Existing machine learning methods for managing sepsis struggle in offline…

Machine Learning · Computer Science 2024-03-13 Dipesh Tamboli , Jiayu Chen , Kiran Pranesh Jotheeswaran , Denny Yu , Vaneet Aggarwal

Paralytic Ileus (PI) patients are at high risk of death when admitted to the Intensive care unit (ICU), with mortality as high as 40\%. There is minimal research concerning PI patient mortality prediction. There is a need for more accurate…

Machine Learning · Computer Science 2021-08-04 Maryam Pishgar , Martha Razo , Julian Theis , Houshang Darabi

Sepsis is a major public health concern due to its high morbidity, mortality, and cost. Its clinical outcome can be substantially improved through early detection and timely intervention. By leveraging publicly available datasets, machine…

Machine Learning · Computer Science 2026-02-04 Yin Jin , Tucker R. Stewart , Deyi Zhou , Chhavi Gupta , Arjita Nema , Scott C. Brakenridge , Grant E. O'Keefe , Juhua Hu

This study employed the MIMIC-IV database as data source to investigate the use of dynamic, high-frequency, multivariate time-series vital signs data, including temperature, heart rate, mean blood pressure, respiratory rate, and SpO2,…

Machine Learning · Computer Science 2023-07-13 Tongyue Shi , Zhilong Zhang , Wentie Liu , Junhua Fang , Jianguo Hao , Shuai Jin , Huiying Zhao , Guilan Kong

Sepsis is a life threatening medical condition that occurs when the body has an extreme response to infection, leading to widespread inflammation, organ failure, and potentially death. Because sepsis can worsen rapidly, early detection is…

Machine Learning · Computer Science 2025-05-07 Oyindolapo O. Komolafe , Zhimin Mei , David Morales Zarate , Gregory William Spangenberg

Motivated by conflicting conclusions regarding hydrocortisone's treatment effect on ICU patients with vasopressor-dependent septic shock, we developed a novel instrumental variable (IV) estimator to assess the average treatment effect (ATE)…

Methodology · Statistics 2025-03-18 Runjia Li , Victor B. Talisa , Chung-Chou H. Chang

Pain management in intensive care usually involves complex trade-offs, since both inadequate and excessive treatment can compromise patient safety. Prior work on reinforcement learning for sedation and analgesia has explored how to optimize…

Machine Learning · Computer Science 2026-05-19 Joel Romero-Hernandez , Oscar Camara

Predicting in-hospital mortality for intensive care unit (ICU) patients is key to final clinical outcomes. AI has shown advantaged accuracy but suffers from the lack of explainability. To address this issue, this paper proposes an…

Machine Learning · Computer Science 2024-01-01 Xingqiao Li , Jindong Gu , Zhiyong Wang , Yancheng Yuan , Bo Du , Fengxiang He
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