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Related papers: Optimal Sepsis Patient Treatment using Human-in-th…

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These two synthetic datasets comprise vital signs, laboratory test results, administered fluid boluses and vasopressors for 3,910 patients with acute hypotension and for 2,164 patients with sepsis in the Intensive Care Unit (ICU). The…

Machine Learning · Computer Science 2021-12-09 Nicholas I-Hsien Kuo , Mark Polizzotto , Simon Finfer , Louisa Jorm , Sebastiano Barbieri

Sepsis is a life-threatening organ malfunction caused by the host's inability to fight infection, which can lead to death without proper and immediate treatment. Therefore, early diagnosis and medical treatment of sepsis in critically ill…

Machine Learning · Computer Science 2023-04-14 Kevin Ewig , Xiangwen Lin , Tucker Stewart , Katherine Stern , Grant O'Keefe , Ankur Teredesai , Juhua Hu

The use of artificial intelligence in clinical care to improve decision support systems is increasing. This is not surprising since, by its very nature, the practice of medicine consists of making decisions based on observations from…

Quantitative Methods · Quantitative Biology 2019-05-03 Isaac Mativo , Yelena Yesha , Michael Grasso , Tim Oates , Qian Zhu

Sepsis is a life-threatening condition triggered by an extreme infection response. Our objective is to forecast sepsis patient outcomes using their medical history and treatments, while learning interpretable state representations to assess…

Machine Learning · Computer Science 2023-11-17 Anna Wong , Shu Ge , Nassim Oufattole , Adam Dejl , Megan Su , Ardavan Saeedi , Li-wei H. Lehman

Timely transition from intravenous (IV) to oral antibiotic therapy shortens hospital stays, reduces catheter-related infections, and lowers healthcare costs, yet one in five patients in England remain on IV antibiotics despite meeting…

Machine Learning · Computer Science 2026-03-10 Magnus Ross , Nel Swanepoel , Akish Luintel , Emma McGuire , Ingemar J. Cox , Steve Harris , Vasileios Lampos

Background Sepsis is one of the most life-threatening circumstances for critically ill patients in the US, while a standardized criteria for sepsis identification is still under development. Disparities in social determinants of sepsis…

Machine Learning · Computer Science 2021-12-16 Hanyin Wang , Yikuan Li , Andrew Naidech , Yuan Luo

We present a machine learning pipeline and model that uses the entire uncurated EHR for prediction of in-hospital mortality at arbitrary time intervals, using all available chart, lab and output events, without the need for pre-processing…

Machine Learning · Computer Science 2019-09-18 Jacob Deasy , Pietro Liò , Ari Ercole

Sepsis is a life threatening condition that requires timely detection in intensive care settings. Traditional machine learning approaches, including Naive Bayes, Support Vector Machine (SVM), Random Forest, and XGBoost, often rely on manual…

Machine Learning · Computer Science 2025-09-03 Hejiang Cai , Di Wu , Ji Xu , Xiang Liu , Yiziting Zhu , Xin Shu , Yujie Li , Bin Yi

The intensive care unit (ICU) comprises a complex hospital environment, where decisions made by clinicians have a high level of risk for the patients' lives. A comprehensive care pathway must then be followed to reduce p complications.…

Heart failure affects millions of people worldwide, significantly reducing quality of life and leading to high mortality rates. Despite extensive research, the relationship between heart failure and mortality rates among ICU patients is not…

Machine Learning · Computer Science 2024-09-04 Negin Ashrafi , Armin Abdollahi , Jiahong Zhang , Maryam Pishgar

Sepsis is a syndrome that develops in the body in response to the presence of an infection. Characterized by severe organ dysfunction, sepsis is one of the leading causes of mortality in Intensive Care Units (ICUs) worldwide. These…

Machine Learning · Computer Science 2023-11-20 Tucker Stewart , Katherine Stern , Grant O'Keefe , Ankur Teredesai , Juhua Hu

Fluid resuscitation, also called fluid therapy, is commonly used in treatment of critical care patients. Of the variables inherent to fluid therapy treatment, fluid infusion types are well-studied, but volumetric optimization is not.…

Systems and Control · Electrical Eng. & Systems 2023-12-12 Jacob Grant , Hossein Mirinejad

We present ICU-Sepsis, an environment that can be used in benchmarks for evaluating reinforcement learning (RL) algorithms. Sepsis management is a complex task that has been an important topic in applied RL research in recent years.…

Machine Learning · Computer Science 2025-03-12 Kartik Choudhary , Dhawal Gupta , Philip S. Thomas

Artificial intelligence (AI) in healthcare has the potential to improve patient outcomes, but clinician acceptance remains a critical barrier. We developed a novel decision support interface that provides interpretable treatment…

Human-Computer Interaction · Computer Science 2023-02-02 Venkatesh Sivaraman , Leigh A. Bukowski , Joel Levin , Jeremy M. Kahn , Adam Perer

With a mortality rate of 5.4 million lives worldwide every year and a healthcare cost of more than 16 billion dollars in the USA alone, sepsis is one of the leading causes of hospital mortality and an increasing concern in the ageing…

Machine Learning · Computer Science 2021-05-12 Margherita Rosnati , Vincent Fortuin

Sepsis is a life-threatening condition with organ dysfunction and is a leading cause of death and critical illness worldwide. Even a few hours of delay in the treatment of sepsis results in increased mortality. Early detection of sepsis…

Sepsis is a life-threatening infectious syndrome associated with high mortality in intensive care units (ICUs). Early and accurate sepsis prediction (SP) is critical for timely intervention, yet remains challenging due to subtle early…

Machine Learning · Computer Science 2025-10-22 Zexi Tan , Tao Xie , Binbin Sun , Xiang Zhang , Yiqun Zhang , Yiu-Ming Cheung

Sepsis accounts for nearly 20% of global ICU admissions, yet conventional prediction models often fail to effectively integrate heterogeneous data streams, remaining either siloed by modality or reliant on brittle early fusion. In this…

Machine Learning · Computer Science 2025-12-18 Ryan Cartularo

The timeliness of detection of a sepsis event in progress is a crucial factor in the outcome for the patient. Machine learning models built from data in electronic health records can be used as an effective tool for improving this…

Detecting and predicting septic shock early is crucial for the best possible outcome for patients. Accurately forecasting the vital signs of patients with sepsis provides valuable insights to clinicians for timely interventions, such as…

Machine Learning · Computer Science 2023-06-27 Anubhav Bhatti , Naveen Thangavelu , Marium Hassan , Choongmin Kim , San Lee , Yonghwan Kim , Jang Yong Kim