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The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

Analysis of structural and functional connectivity (FC) of human brains is of pivotal importance for diagnosis of cognitive ability. The Human Connectome Project (HCP) provides an excellent source of neural data across different regions of…

Applications · Statistics 2020-07-10 Satwik Acharyya , Zhengwu Zhang , Anirban Bhattacharya , Debdeep Pati

A large number of surface-based analyses on brain imaging data adopt some specific brain atlases to better assess structural and functional changes in one or more brain regions. In these analyses, it is necessary to obtain an anatomically…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Wen Zhang , Yalin Wang

An essential premise for neuroscience brain network analysis is the successful segmentation of the cerebral cortex into functionally homogeneous regions. Resting-state functional magnetic resonance imaging (rs-fMRI), capturing the…

Neurons and Cognition · Quantitative Biology 2023-09-20 Xiaoxiao Ma , Chunzhi Yi , Zhicai Zhong , Hui Zhou , Baichun Wei , Haiqi Zhu , Feng Jiang

Label distribution learning (LDL) is a general learning framework, which assigns to an instance a distribution over a set of labels rather than a single label or multiple labels. Current LDL methods have either restricted assumptions on the…

Machine Learning · Computer Science 2017-10-18 Wei Shen , Kai Zhao , Yilu Guo , Alan Yuille

Resting-state fMRI has been shown to provide surrogate biomarkers for the analysis of various diseases. In addition, fMRI data helps in understanding the brain's functional working during resting state and task-induced activity. To improve…

Machine Learning · Computer Science 2021-10-11 Dushyant Sahoo , Christos Davatzikos

In many modern applications, including analysis of gene expression and text documents, the data are noisy, high-dimensional, and unordered--with no particular meaning to the given order of the variables. Yet, successful learning is often…

Methodology · Statistics 2008-07-25 Ann B. Lee , Boaz Nadler , Larry Wasserman

Within a supervised classification framework, labeled data are used to learn classifier parameters. Prior to that, it is generally required to perform dimensionality reduction via feature extraction. These preprocessing steps have motivated…

Computer Vision and Pattern Recognition · Computer Science 2017-12-04 Adrien Lagrange , Mathieu Fauvel , Stéphane May , Nicolas Dobigeon

Brain segmentation at different levels is generally represented as hierarchical trees. Brain regional atrophy at specific levels was found to be marginally associated with Alzheimer's disease outcomes. In this study, we propose an L1-type…

Applications · Statistics 2021-04-02 Yi Zhao , Bingkai Wang , Chin-Fu Liu , Andreia V. Faria , Michael I. Miller , Brian S. Caffo , Xi Luo

Humans perceive the world as a series of sequential events, which can be hierarchically organized with different levels of abstraction based on conceptual knowledge. Drawing inspiration from human learning behaviors, this work proposes a…

Machine Learning · Computer Science 2025-03-11 Quyen Tran , Hoang Phan , Minh Le , Tuan Truong , Dinh Phung , Linh Ngo , Thien Nguyen , Nhat Ho , Trung Le

Predictive uncertainty estimation remains a challenging problem precluding the use of deep neural networks as subsystems within safety-critical applications. Aleatoric uncertainty is a component of predictive uncertainty that cannot be…

Machine Learning · Computer Science 2023-12-12 Angel Daruna , Yunye Gong , Abhinav Rajvanshi , Han-Pang Chiu , Yi Yao

Tree kernels have demonstrated their ability to deal with hierarchical data, as the intrinsic tree structure often plays a discriminative role. While such kernels have been successfully applied to various domains such as nature language…

Computer Vision and Pattern Recognition · Computer Science 2016-04-08 Yanwei Cui , Laetitia Chapel , Sébastien Lefèvre

With the advent of highly predictive but opaque deep learning models, it has become more important than ever to understand and explain the predictions of such models. Existing approaches define interpretability as the inverse of complexity…

Cytoarchitectonic mapping provides anatomically grounded parcellations of brain structure and forms a foundation for integrative, multi-modal neuroscience analyses. These parcellations are defined based on the shape, density, and spatial…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Shiqi Zhang , Fang Xu , Pengcheng Zhou

Decomposing predictive uncertainty into epistemic (model ignorance) and aleatoric (data ambiguity) components is central to reliable decision making, yet most methods estimate both from the same predictive distribution. Recent empirical and…

Machine Learning · Computer Science 2026-02-13 Tanmoy Mukherjee , Marius Kloft , Pierre Marquis , Zied Bouraoui

Hierarchies feature prominently in anatomical accounts of cortical organisation. An open question is which computational (algorithmic) processes are implemented by these hierarchies. One renowned hypothesis is that cortical hierarchies…

Neurons and Cognition · Quantitative Biology 2017-09-08 Andreea O. Diaconescu , Vladimir Litvak , Christoph Mathys , Lars Kasper , Karl J. Friston , Klaas E. Stephan

Uncertainty maps highlight unreliable regions in segmentation predictions. However, most uncertainty evaluation metrics treat voxels independently, ignoring spatial context and anatomical structure. As a result, they may assign identical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Tal Zeevi , Eléonore V. Lieffrig , Lawrence H. Staib , John A. Onofrey

Supervised machine learning often requires large training sets to train accurate models, yet obtaining large amounts of labeled data is not always feasible. Hence, it becomes crucial to explore active learning methods for reducing the size…

Machine Learning · Computer Science 2024-04-16 Ashna Jose , Emilie Devijver , Massih-Reza Amini , Noel Jakse , Roberta Poloni

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

Inverse inference, or "brain reading", is a recent paradigm for analyzing functional magnetic resonance imaging (fMRI) data, based on pattern recognition and statistical learning. By predicting some cognitive variables related to brain…