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This article experimentally examines different configurations of a novel multi-camera array microscope (MCAM) imaging technology. The MCAM is based upon a densely packed array of "micro-cameras" to jointly image across a large field-of-view…

Far-field super-resolution fluorescence microscopy has been rapidly developed for applications ranging from cell biology to nanomaterials. However, it remains a significant challenge to achieve super-resolution imaging at depth in opaque…

Optics · Physics 2024-05-01 Tengfei Wu , YoonSeok Baek , Fei Xia , Sylvain Gigan , Hilton B. de Aguiar

Owing to its capacity for unique (bio)-chemical specificity, microscopy withmid-IR illumination holds tremendous promise for a wide range of biomedical and industrial applications. The primary limitation, however, remains detection; with…

Recent theoretical and experimental studies have shown that imaging with resolution well beyond the diffraction limit can be obtained with so-called superlenses. Images formed by such superlenses are, however, in the near field only, or a…

Optics · Physics 2009-11-11 Stephane Durant , Zhaowei Liu , Nicholas Fang , Xiang Zhang

Super-resolution Structured Illumination Microscopy (SR-SIM) enables fluorescence microscopy beyond the diffraction limit at high frame rates. Compared to other super-resolution microscopy techniques, the low photon fluence used in SR-SIM…

This paper presents a simple and effective method to fabricate a polydimethyl-siloxane (PDMS) microlens array with a high fill factor, which utilizes the UV proximity printing and photoresist replication methods. The concave microlens array…

Other Computer Science · Computer Science 2007-11-29 Tsung-Hung Lin , Hsiharng Yang , Ching-Kong Chao

We present an epi-illumination multi-camera array microscope (epi-MCAM) designed for wide-field reflective imaging of non-transparent samples. The epi-MCAM contains 24 tightly packed and synchronized epi-illumination microscope units,…

Fluorescence imaging is an essential diagnostic tool in many fields, but diffraction-limited optical imaging at depth is limited by scattering. Here, we present a method based on multiple random illuminations, combined with a computational…

Optics · Physics 2026-03-30 Lei Zhu , Tengfei Wu , Bernhard Rauer , Hilton B. de Aguiar , Sylvain Gigan

We experimentally probe complex bio-photonic architecture of microstructures on the transparent insect wings by a simple, non-invasive, real time optical technique. A stable and reproducible far-field diffraction pattern in transmission was…

This paper proposes a non-computational method of counteracting the effect of image degradation introduced by the diffraction phenomenon in lensless microscopy. All the optical images (whether focused by lenses or not) are diffraction…

Optics · Physics 2021-04-08 Sanjeev Kumar , Manjunatha Mahadevappa , Pranab Kumar Dutta

Video-rate super-resolution imaging through biological tissue can visualize and track biomolecule interplays and transportations inside cellular organisms. Structured illumination microscopy allows for wide-field super resolution…

Fluorescence microscopy is indispensable in nanoscience and biological sciences. The versatility of labeling target structures with fluorescent dyes permits to visualize structure and function at a subcellular resolution with a wide field…

Digital micromirror device (DMD) serves in a significant part of computational optical setups as a means of encoding an image by the desired pattern. The most prominent is its usage in the so-called single-pixel camera experiment. This…

Instrumentation and Detectors · Physics 2020-06-24 Lukas Klein , Karel Zidek

Recent theoretical work suggested upper bounds on the operating bandwidths of flat lenses. Here, we show how these bounds can be circumvented via a multi-level diffractive lens (MDL) of diameter = 100 mm, focal length = 200 mm, device…

Optics · Physics 2022-01-03 Apratim Majumder , Monjurul Meem , Nicole Brimhall , Rajesh Menon

Optical photothermal microscopy is a powerful, emerging method that overcomes the diffraction limit in infrared hyperspectral imaging by utilizing a visible probe laser beam to detect local temperature-induced modulation at the visible…

We experimentally demonstrate imaging in the longwave-infrared (LWIR) spectral band (8um to 12um) using a single polymer flat lens based upon multi-level diffractive optics. The device thickness is only 10{\mu}m, and chromatic aberrations…

Infrared avalanche photodiode arrays represent a panacea for many branches of astronomy by enabling extremely low-noise, high-speed and even photon-counting measurements at near-infrared wavelengths. We recently demonstrated the use of an…

Instrumentation and Methods for Astrophysics · Physics 2015-08-19 Christoph Baranec , Dani Atkinson , Reed Riddle , Donald Hall , Shane Jacobson , Nicholas M. Law , Mark Chun

It has previously been demonstrated that model-based reconstruction methods relying on a priori knowledge of the imaging point spread function (PSF) coupled to sparsity priors on the object to image can provide super-resolution in…

Image and Video Processing · Electrical Eng. & Systems 2019-10-02 Sergey Vilov , Bastien Arnal , Eliel Hojman , Yonina C. Eldar , Ori Katz , Emmanuel Bossy

Achieving high spatial resolution is the goal of many imaging systems. Designing a high-resolution lens with diffraction-limited performance over a large field of view remains a difficult task in imaging system design. On the other hand,…

We present the experimental observation of the superlensing effect in a slab of a one-dimensional photonic crystal made of tilted dielectric elements. We show that this flat lens can achieve subwavelength resolution in different frequency…

Optics · Physics 2015-05-13 Salvatore Savo , Emiliano Di Gennaro , Antonello Andreone
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