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Although suppressing the spread of a disease is usually achieved by investing in public resources, in the real world only a small percentage of the population have access to government assistance when there is an outbreak, and most must…

Physics and Society · Physics 2018-02-14 Xiaolong Chen , Ruijie Wang , Ming Tang , Shimin Cai , H. Eugene Stanley , Lidia A. Braunstein

We formulate a general SEIR epidemic model in a heterogenous population characterized by some trait in a discrete or continuous subset of a space R d. The incubation and recovery rates governing the evolution of each homogenous…

Analysis of PDEs · Mathematics 2023-03-03 Luís Almeida , Pierre-Alexandre Bliman , Grégoire Nadin , Benoît Perthame , Nicolas Vauchelet

SIRS epidemic models assume that individual immunity (from infection and vaccination) wanes in one big leap, from complete immunity to complete susceptibility. For many diseases immunity on the contrary wanes gradually, something that's…

Populations and Evolution · Quantitative Biology 2022-11-17 Mohamed El Khalifi , Tom Britton

Understanding the influence of an environment on the evolution of its resident population is a major challenge in evolutionary biology. Great progress has been made in homogeneous population structures while heterogeneous structures have…

Populations and Evolution · Quantitative Biology 2014-07-30 Wes Maciejewski , Gregory J. Puleo

We consider a model for an influenza-like disease, in which, between seasons, the virus makes a random genetic drift $\delta$, (reducing immunity by the factor $\delta$) and obtains a new random transmissibility $\tau$ (closely related to…

Probability · Mathematics 2025-05-26 Tom Britton , Andrea Pugliese

We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and…

Populations and Evolution · Quantitative Biology 2024-11-22 Félix Foutel-Rodier , Arthur Charpentier , Hélène Guérin

The current survey paper concerns stochastic mathematical models for the spread of infectious diseases. It starts with the simplest setting of a homogeneous population in which a transmittable disease spreads during a short outbreak.…

Applications · Statistics 2018-01-30 Tom Britton

The synthetic control method is an empirical methodology forcausal inference using observational data. By observing thespread of COVID-19 throughout the world, we analyze the dataon the number of deaths and cases in different regions…

Computers and Society · Computer Science 2020-09-29 Niloofar Bayat , Cody Morrin , Yuheng Wang , Vishal Misra

In many real-world complex systems, individuals have many kind of interactions among them, suggesting that it is necessary to consider a layered structure framework to model systems such as social interactions. This structure can be…

Physics and Society · Physics 2015-02-06 C. Buono , L. A. Braunstein

In recent studies, it has been shown that a cooperative interaction in a co-infection spread can lead to a discontinuous transition at a decreased threshold. Here, we investigate effects of immunization with a rate proportional to the…

Populations and Evolution · Quantitative Biology 2022-05-02 Adib Khazaee , Fakhteh Ghanbarnejad

We study an infection-age structured epidemic model in which both the infectivity and the rate of loss of immunity depend on the time-since-infection. The model can be equivalently viewed as a nonlinear renewal equation for the incidence of…

Dynamical Systems · Mathematics 2025-11-13 Francesca Scarabel , Harry Coldwell , Tyler Cassidy

Epidemic spreading is well understood when a disease propagates around a contact graph. In a stochastic susceptible-infected-susceptible setting, spectral conditions characterise whether the disease vanishes. However, modelling human…

Social and Information Networks · Computer Science 2021-09-15 Desmond John Higham , Henry-Louis de Kergorlay

The epidemic threshold of a spreading process indicates the condition for the occurrence of the wide spreading regime, thus representing a predictor of the network vulnerability to the epidemic. Such threshold depends on the natural history…

Physics and Society · Physics 2016-01-20 Eugenio Valdano , Chiara Poletto , Vittoria Colizza

I study the spreading of infectious diseases on heterogeneous populations. I represent the population structure by a contact-graph where vertices represent agents and edges represent disease transmission channels among them. The population…

Populations and Evolution · Quantitative Biology 2009-11-13 Alexei Vazquez

We study a general epidemic model with arbitrary recovery rate distributions. This simple deviation from the standard setup is sufficient to prove that heterogeneity in the dynamical parameters can be as important as the more studied…

Physics and Society · Physics 2020-01-22 Guilherme Ferraz de Arruda , Giovanni Petri , Francisco A. Rodrigues , Yamir Moreno

One of the critical measures to control infectious diseases is a lockdown. Once past the lockdown stage in many parts of the world, the crucial question now concerns the effects of relaxing the lockdown and finding the best ways to…

Populations and Evolution · Quantitative Biology 2025-10-14 Ravi Kiran , Madhumita Roy , Syed Abbas , A. Taraphder

We use a stochastic metapopulation model to study the combined effects of seasonality and spatial heterogeneity on disease persistence. We find a pronounced effect of enhanced persistence associated with strong heterogeneity, intermediate…

Populations and Evolution · Quantitative Biology 2015-02-23 Ganna Rozhnova , Ana Nunes , Alan J. McKane

We present a compartmental meta-population model for the spread of Covid-19 in India. Our model simulates populations at a district or state level using an epidemiological model that is appropriate to Covid-19. Different districts are…

In the recent COVID-19 pandemic we assisted at a sequence of epidemic waves intertwined by anomalous fade-outs with periods of low but persistent epidemic prevalence. These long-living epidemic states complicate epidemic control and…

Physics and Society · Physics 2025-08-27 Javier Aguilar , Beatriz Arregui García , Raúl Toral , Sandro Meloni , Jose J. Ramasco