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Physarum Polycephalum is a slime mold that is apparently able to solve shortest path problems. A mathematical model has been proposed by biologists to describe the feedback mechanism used by the slime mold to adapt its tubular channels…

Data Structures and Algorithms · Computer Science 2019-07-01 Vincenzo Bonifaci , Kurt Mehlhorn , Girish Varma

In this paper we study dynamics inspired by Physarum polycephalum (a slime mold) for solving linear programs [NTY00, IJNT11, JZ12]. These dynamics are arrived at by a local and mechanistic interpretation of the inner workings of the slime…

Data Structures and Algorithms · Computer Science 2015-11-24 Damian Straszak , Nisheeth K. Vishnoi

A supply chain is a system which moves products from a supplier to customers. The supply chains are ubiquitous. They play a key role in all economic activities. Inspired by biological principles of nutrients' distribution in protoplasmic…

Neural and Evolutionary Computing · Computer Science 2014-03-24 Xiaoge Zhang , Andrew Adamatzky , Xin-She Yang , Hai Yang , Sankaran Mahadevan , Yong Deng

Physarum Polycephalum is a slime mold that can solve shortest path problems. A mathematical model based on Physarum's behavior, known as the Physarum Directed Dynamics, can solve positive linear programs. In this paper, we present a family…

Data Structures and Algorithms · Computer Science 2022-07-19 Yuan Gao , Hamidreza Kamkari , Andreas Karrenbauer , Kurt Mehlhorn , Mohammadamin Sharifi

Optimization of fluid transport in the slime mold Physarum polycephalum has been the subject of several modeling efforts in recent literature. Existing models assume that the tube adaptation mechanism in P. polycephalum's tubular network is…

Tissues and Organs · Quantitative Biology 2019-07-01 Vincenzo Bonifaci

The true slime mould Physarum polycephalum is a recent well studied example of how complex transport networks emerge from simple auto-catalytic and self- organising local interactions, adapting structure and function against changing…

Emerging Technologies · Computer Science 2015-03-29 Jeff Jones

In the realm of biological flow networks, the ability to dynamically adjust to varying demands is paramount. Drawing inspiration from the remarkable adaptability of Physarum polycephalum, we present a novel physical mechanism tailored to…

Soft Condensed Matter · Physics 2023-10-05 Vidyesh Rao Anisetti , Ananth Kandala , J. M. Schwarz

The true slime mold \textit{Physarum polycephalum} has the remarkable capability to perform self-organized activities such as network formation among food sources. Despite well reproducing the emergence of slime networks, existing models…

Populations and Evolution · Quantitative Biology 2025-08-04 Damiano Reginato , Daniele Proverbio , Giulia Giordano

The slime mould Physarum polycephalum displays adaptive transport dynamics and network formation that have inspired its use as a model of biological computation. We develop a Lagrangian formulation of Physarum's adaptive dynamics on…

Neurons and Cognition · Quantitative Biology 2025-11-12 Ricard Solé , Jordi Pla-Mauri

Physarum polycephalum is an acellular slime mould that grows as a highly adaptive network of veins filled with protoplasm. As it forages, Physarum dynamically rearranges its network structure as a response to local stimuli information,…

Fluid Dynamics · Physics 2023-05-23 Rodrigo Almeida , Rui Dilão

Physarum Polycephalum is a unicellular slime mold that has been intensely studied due to its ability to solve mazes, find shortest paths, generate Steiner trees, share knowledge, remember past events, and its applications to unconventional…

Biological Physics · Physics 2022-10-18 Sheryl Hsu , Laura P. Schaposnik

Physarum polycephalum is a single-celled, multi-nucleated slime mold whose body constitutes a network of veins. As it explores its environment, it adapts and optimizes its network to external stimuli. It has been shown to exhibit complex…

Fluid Dynamics · Physics 2023-09-20 Ana Filipa Valente

In this work we study and expand a model describing the dynamics of a unicellular slime mold, Physarum Polycephalum (PP), which was proposed to simulate the ability of PP to find the shortest path connecting two food sources in a maze. The…

Numerical Analysis · Mathematics 2020-09-29 Enrico Facca , Franco Cardin , Mario Putti

Many studies have shown that Physarum polycephalum slime mold is able to find the shortest path in a maze. In this paper we study this behavior in a network, using a hyperbolic model of chemotaxis. Suitable transmission and boundary…

Numerical Analysis · Mathematics 2016-01-07 Gabriella Bretti , Roberto Natalini

Slime mould Physarum polycephalum is large single cell with intriguingly smart behaviour. The slime mould shows outstanding abilities to adapt its protoplasmic network to varying environmental conditions. The slime mould can solve tasks of…

Emerging Technologies · Computer Science 2013-04-09 Andrew Adamatzky , Rachel Armstrong , Jeff Jones , Yukio-Pegio Gunji

True slime mould Physarum polycephalum approximates a range of complex computations via growth and adaptation of its proto- plasmic transport network, stimulating a large body of recent research into how such a simple organism can perform…

Emerging Technologies · Computer Science 2015-03-12 Jeff Jones , Andrew Adamatzky

Active fluid transport is a hallmark of many biological transport networks. While animal circulatory systems generally rely on a single heart to drive flows, other organisms employ decentralized local pumps to distribute fluids and…

Biological Physics · Physics 2024-01-04 Adam B. Dionne , Katharine E. Jensen , Henrik Ronellenfitsch

A fundamental question regarding biological transport networks is the interplay between the network development or reorganization and the flows it carries. We use Physarum polycephalum, a true slime mould with a transport network which…

Biological Physics · Physics 2022-12-27 Raphaël Saiseau , Valentin Busson , Laura Xénard , Marc Durand

We consider a system of nonlinear ordinary differential equations for the solution of linear programming (LP) problems that was first proposed in the mathematical biology literature as a model for the foraging behavior of acellular slime…

Optimization and Control · Mathematics 2021-03-30 Vincenzo Bonifaci

The giant single-celled slime mould Physarum polycephalum has inspired rapid develop- ments in unconventional computing substrates since the start of this century. This is primarily due to its simple component parts and the distributed…

Emerging Technologies · Computer Science 2015-11-19 Jeff Jones
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