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Spectral computed tomography (CT) can reconstruct spectral images from different energy bins using photon counting detectors (PCDs). However, due to the limited photons and counting rate in the corresponding spectral fraction, the…

Medical Physics · Physics 2020-10-28 Xiang Chen , Wenjun Xia , Yan Liu , Hu Chen , Jiliu Zhou , Yi Zhang

Mid-infrared spectroscopy probes molecular vibrations to identify chemical species and functional groups. Therefore, mid-infrared hyperspectral imaging is one of the most powerful and promising candidates for chemical imaging using optical…

Optics · Physics 2023-07-06 Yue Zhao , Shota Kusama , Yuji Furutani , Wei-Hong Huang , Chih-Wei Luo , Takao Fuji

Novel techniques are currently being developed and established for the accurate chemical analysis and detection of single cancer cells, single embryos and single seeds by Fourier Transform Near Infrared (FT-NIR) Microspectroscopy, Fourier…

Tissues and Organs · Quantitative Biology 2007-05-23 I. C. Baianu , D. Costescu , N. E. Hofmann , S. S. Korban

We report on Mid-infrared (MIR) OCT at 4 $\mu$m based on collinear sum-frequency upconversion and promote the A-scan scan rate to 3 kHz. We demonstrate the increased imaging speed for two spectral realizations, one providing an axial…

We discuss the Surface-Plasmon-Resonance (SPR) technique based on Fourier -Transform - InfraRed (FTIR) spectrometry. We explore the potential of the infrared surface plasmon resonance technique for biological studies in aqueous solutions…

Biological Physics · Physics 2010-02-03 M. Golosovsky , V. Lirtsman , V. Yashunsky , D. Davidov , B. Aroeti

Fourier transform spectroscopy based on incoherent light sources is a well-established tool in research fields from molecular spectroscopy and atmospheric monitoring to material science and biophysics. It provides broadband molecular…

We propose an on-chip mid-infrared (MIR) photonic spectroscopy platform for aerosol characterization to obtain highly discriminatory information on the chemistry of aerosol particles. Sensing of aerosols is crucial for various…

Applied Physics · Physics 2020-05-12 Robin Singh , Peter Su , Lionel Kimerling , Anu Agarwal , Brian W Anthony

Atomic Force Microscopy - Infrared (AFM-IR) has emerged as a useful technique for measuring absorption spectra with spatial resolution better than the optical diffraction limit. The technique relies on the movement of a probe for atomic…

Applied Physics · Physics 2024-01-17 Luca Quaroni

Safe and efficient intracellular delivery of genes or drugs is critically important in targeted cancer treatment and gene therapy applications. Ultrasound (US) has been demonstrated to alter the cell membrane permeability due to a…

We experimentally demonstrate wide-band (>100 THz) frequency down-conversion of near-infrared (NIR) femtosecond-scale pulses from an Er:fiber laser to the mid-infrared (MIR) using four-wave-mixing (FWM) in photonic-chip silicon-nitride…

Edge-enhanced imaging is critical for visualizing weakly absorbing and transparent objects. Extending this functionality into the mid-infrared (MIR) region enables chemical sensitivity and improved imaging performance for biomedical,…

We have developed a digital fast Fourier transform (FFT) spectrometer made of an analog-to-digital converter (ADC) and a field-programmable gate array (FPGA). The base instrument has independent ADC and FPGA modules, which allow us to…

Instrumentation and Methods for Astrophysics · Physics 2017-07-26 Kazumasa Iwai , Yûki Kubo , Hiromitsu Ishibashi , Takahiro Naoi , Kenichi Harada , Kenji Ema , Yoshinori Hayashi , Yuichi Chikahiro

We provide a detailed description of the Herschel-SPIRE Fourier Transform Spectrometer (FTS) Spectral Feature Finder (FF). The FF is an automated process designed to extract significant spectral features from SPIRE FTS data products.…

Instrumentation and Methods for Astrophysics · Physics 2020-06-24 R. Hopwood , I. Valtchanov , Locke D. Spencer , J. P. Scott , C. S. Benson , N. Marchili , N. Hladczuk , E. T. Polehampton , N. Lu , G. Makiwa , D. A. Naylor , B. G. Gom , G. Noble , M. J. Griffin

IR spectroscopy has been widely used for chemical identification and quantitative analysis of reactions occurring in a specific time and space domains by measuring an average signal of the entire system1. Achieving IR measurements with…

Vibrational spectroscopy is a cornerstone technique for molecular characterization and offers an ideal target for the computational investigation of molecular materials. Building on previous comprehensive assessments of efficient methods…

Fluorescence-detected Fourier transform (FT) spectroscopy is a technique in which the relative paths of an optical interferometer are controlled to excite a material sample, and the ensuing fluorescence is detected as a function of the…

The sensitivity of molecular fingerprinting is dramatically improved when placing the absorbing sample in a high-finesse optical cavity, thanks to the large increase of the effective path-length. As demonstrated recently, when the…

Fourier imaging is an indirect imaging method which records the diffraction pattern of the object scene coherently in the focal plane of the imaging system and reconstructs the image using computational resources. The spatial resolution,…

Optics · Physics 2023-06-05 Hui Yuan , Alvydas Lisauskas , Mark D. Thomson , Hartmut G. Roskos

We present EMIR, a powerful near-infrared (NIR) camera and multi-object spectrograph (MOS) installed at the Nasmyth focus of the 10.4 m GTC. EMIR was commissioned in mid-2016 and is offered as a common-user instrument. It provides spectral…

Model-Based Iterative Reconstruction (MBIR) is important because direct methods, such as Filtered Back-Projection (FBP) can introduce significant noise and artifacts in sparse-angle tomography, especially for time-evolving samples. Although…

Mathematical Software · Computer Science 2026-03-31 Dinesh Kumar , Jeffrey Donatelli
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