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Hyperspectral imaging provides high-dimensional spatial-temporal-spectral information revealing intrinsic matter characteristics. Here we report an on-chip computational hyperspectral imaging framework with high spatial and temporal…

High-speed multiplex imaging of fluorescent probes is limited by a combination of spectral resolution, sensitivity, high cost and low light throughput of detectors, and filters. In this work, we present a hyperspectral detection system…

We report a novel microscopy platform, termed Multi-Aperture Fourier ptychographic microscopy (MA-FPM), capable of realizing gigapixel complex field images with large data acquisition bandwidths - in gigapixels per second. MA-FPM is a…

Optics · Physics 2020-10-14 Pavan Chandra Konda , Jonathan M. Taylor , Andrew R. Harvey

The fitting of spectral lines is a common step in the analysis of line observations and simulations. However, the observational noise, the presence of multiple velocity components, and potentially large data sets make it a non-trivial task.…

Astrophysics of Galaxies · Physics 2024-03-08 Mika Juvela , Devika Tharakkal

Full-color imaging is significant in digital pathology. Compared with a grayscale image or a pseudo-color image that only contains the contrast information, it can identify and detect the target object better with color texture information.…

Image and Video Processing · Electrical Eng. & Systems 2022-04-26 Yuting Gao , Jiurun Chen , Aiye Wang , An Pan , Caiwen Ma , Baoli Yao

Nuclear magnetic resonance (NMR) spectroscopy exploits the magnetic properties of atomic nuclei to discover the structure, reaction state and chemical environment of molecules. We propose a probabilistic generative model and inference…

We report experimental results of parallel measurement of spectral components of the light. The temporal fluctuations of an optical field mixed with a separate reference are recorded with a high throughput complementary metal oxide…

Optics · Physics 2008-11-26 Michael Atlan , Michel Gross

Infrared spectroscopy in the spectral fingerprint region from 6-12 um accesses the largest molecular absorption cross-sections, permitting sensitive, quantitative and species-specific measurements. Here, we show how dual-comb…

Optics · Physics 2023-06-26 O. Kara , L. Maidment , T. Gardiner , P. G. Schunemann , D. T. Reid

We demonstrate mid-infrared (MIR) frequency combs at 10 GHz repetition rate via intra-pulse difference-frequency generation (DFG) in quasi-phase-matched nonlinear media. Few-cycle pump pulses ($\mathbf{\lesssim}$15 fs, 100 pJ) from a…

Photosensitive proteins embedded in the cell membrane (about 5 nm thickness) act as photoactivated proton pumps, ion gates, enzymes, or more generally, as initiators of stimuli for the cell activity. They are composed of a protein backbone…

Miniaturized spectrometers hold great promise for in situ, in vitro, and even in vivo sensing applications. However, their size reduction imposes vital performance constraints in meeting the rigorous demands of spectroscopy, including fine…

Waveguide-integrated mid-infrared (MIR) photodetectors are pivotal components for the development of molecular spectroscopy applications, leveraging mature photonic integrated circuit (PIC) technologies. Despite various strategies, critical…

Resolving sources beyond the diffraction limit is important in imaging, communications, and metrology. Current image-based methods of super-resolution require phase information (either of the source points or an added filter) and perfect…

Optics · Physics 2025-12-16 S. A. Wadood , Shaurya Aarav , Kevin Liang , Jason W Fleischer

We present ultra-fast quantum chemical methods for the calculation of infrared and ultraviolet-visible spectra designed to provide fingerprint information during autonomous and interactive explorations of molecular structures.…

Chemical Physics · Physics 2022-08-30 Francesco Bosia , Thomas Weymuth , Markus Reiher

Dual-comb spectroscopy has been proven a powerful tool in molecular characterization, which remains challenging to implement in the mid-infrared region due to difficulties in the realization of two mutually locked comb sources and efficient…

Molecular fingerprinting through absorption spectroscopy is a powerful analytical method. Wide spectral ranges are explored with Doppler-limited resolution. Fast data acquisition, accurate measurements of frequency, intensity, and line…

Optics · Physics 2008-08-20 Julien Mandon , Guy Guelachvili , Nathalie Picqué

The mid-infrared (MIR) spectral range is of immense use for civilian and military applications. The large number of vibrational absorption bands in this range can be used for gas sensing, process control and spectroscopy. In addition, there…

Recent spectroscopic observations by sensitive radio telescopes require accurate molecular spectral line frequencies to identify molecular species in a forest of lines detected. To measure rest frequencies of molecular spectral lines in the…

Instrumentation and Methods for Astrophysics · Physics 2021-01-27 Yoshimasa Watanabe , Yutaro Chiba , Takeshi Sakai , Akemi Tamanai , Rikako Suzuki , Nami Sakai

We have constructed a Fourier-transform spectrometer (FTS) operating between 50 and 330 GHz with minimum volume (355 x260 x64 mm) and weight (13 lbs) while maximizing optical throughput (100 $\mathrm{mm}^2$ sr) and optimizing the spectral…

Instrumentation and Methods for Astrophysics · Physics 2019-09-04 Zhaodi Pan , Mira Liu , Ritoban Basu Thakur , Bradford A. Benson , Dale J. Fixsen , Hazal Goksu , Eleanor Rath , Stephan S. Meyer

High-quality Fourier Transform Infrared (FTIR) imaging usually needs extensive signal averaging to reduce noise and drift which severely limits clinical speed. Deep learning can accelerate imaging by reconstructing spectra from rapid,…

Image and Video Processing · Electrical Eng. & Systems 2026-01-30 Azadeh Mokari , Shravan Raghunathan , Artem Shydliukh , Oleg Ryabchykov , Christoph Krafft , Thomas Bocklitz
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