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Drug-Drug Interactions (DDIs) may hamper the functionalities of drugs, and in the worst scenario, they may lead to adverse drug reactions (ADRs). Predicting all DDIs is a challenging and critical problem. Most existing computational models…
A large number of people suffer from life-threatening cardiac abnormalities, and electrocardiogram (ECG) analysis is beneficial to determining whether an individual is at risk of such abnormalities. Automatic ECG classification methods,…
When Deep Neural Networks (DNNs) are used in safety-critical systems, engineers should determine the safety risks associated with failures (i.e., erroneous outputs) observed during testing. For DNNs processing images, engineers visually…
Psychometric assessment instruments aid clinicians by providing methods of assessing the future risk of adverse events such as aggression. Existing machine learning approaches have treated this as a classification problem, predicting the…
Objective: To develop an effective and scalable individual-level patient cost prediction method by automatically learning hidden temporal patterns from multivariate time series data in patient insurance claims using a convolutional neural…
Accurate and timely detection of medical adverse events (AEs) from free-text medical narratives is challenging. Natural language processing (NLP) with deep learning has already shown great potential for analyzing free-text data, but its…
This work introduces Neural Chronos Ordinary Differential Equations (Neural CODE), a deep neural network architecture that fits a continuous-time ODE dynamics for predicting the chronology of a system both forward and backward in time. To…
The United States is experiencing an opioid epidemic, and there were more than 10 million opioid misusers aged 12 or older each year. Identifying patients at high risk of Opioid Use Disorder (OUD) can help to make early clinical…
In order to find effective treatments for Alzheimer's disease (AD), we need to identify subjects at risk of AD as early as possible. To this end, recently developed disease progression models can be used to perform early diagnosis, as well…
Predicting the health risks of patients using Electronic Health Records (EHR) has attracted considerable attention in recent years, especially with the development of deep learning techniques. Health risk refers to the probability of the…
The explosive growth and increasing sophistication of Android malware call for new defensive techniques that are capable of protecting mobile users against novel threats. In this paper, we first extract the runtime Application Programming…
Identification and verification of molecular properties such as side effects is one of the most important and time-consuming steps in the process of molecule synthesis. For example, failure to identify side effects before submission to…
The emergence of deep learning led to the broad usage of neural networks in the time series domain for various applications, including finance and medicine. While powerful, these models are prone to adversarial attacks: a benign targeted…
Coastal regions in North America face major threats from storm surges caused by hurricanes and nor'easters. Traditional numerical models, while accurate, are computationally expensive, limiting their practicality for real-time predictions.…
Anomaly detection is facing with emerging challenges in many important industry domains, such as cyber security and online recommendation and advertising. The recent trend in these areas calls for anomaly detection on time-evolving data…
In realistic scenarios, multivariate timeseries evolve over case-by-case time-scales. This is particularly clear in medicine, where the rate of clinical events varies by ward, patient, and application. Increasingly complex models have been…
Social media is an useful platform to share health-related information due to its vast reach. This makes it a good candidate for public-health monitoring tasks, specifically for pharmacovigilance. We study the problem of extraction of…
The widespread application of machine learning techniques to biomedical data has produced many new insights into disease progression and improving clinical care. Inspired by the flexibility and interpretability of graphs (networks), as well…
Precision medicine tailored to individual patients has gained significant attention in recent times. Machine learning techniques are now employed to process personalized data from various sources, including images, genetics, and…
Deep Neural Networks (DNNs) have been shown vulnerable to Test-Time Evasion attacks (TTEs, or adversarial examples), which, by making small changes to the input, alter the DNN's decision. We propose an unsupervised attack detector on DNN…