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Diabetic retinopathy (DR) results in vision loss if not treated early. A computer-aided diagnosis (CAD) system based on retinal fundus images is an efficient and effective method for early DR diagnosis and assisting experts. A…
Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and…
Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagnoses (anchors) was used to recover missing values in EHR…
Access to real-world healthcare data is limited by stringent privacy regulations and data imbalances, hindering advancements in research and clinical applications. Synthetic data presents a promising solution, yet existing methods often…
Randomized controlled trials (RCTs) are the standard for evaluating the effectiveness of clinical interventions. To address the limitations of RCTs on real-world populations, we developed a methodology that uses a large observational…
Stroke affected millions annually, yet poor symptom recognition often delayed care-seeking. To address risk recognition gap, we developed a passive surveillance system for early stroke risk detection using patient-reported symptoms among…
Diabetes, especially T2DM, continues to be a significant health problem. One of the major concerns associated with diabetes is the development of its complications. Diabetic nephropathy, one of the chronic complication of diabetes,…
Chronic Kidney Disease (CKD) represents a significant global health challenge, characterized by the progressive decline in renal function, leading to the accumulation of waste products and disruptions in fluid balance within the body. Given…
Accurate prediction of cardiovascular disease (CVD) risk is crucial for healthcare institutions. This study addresses the growing prevalence of diabetes and its strong link to heart disease by proposing an efficient CVD risk prediction…
Medical Anomaly Detection (MedAD) presents a significant opportunity to enhance diagnostic accuracy using Large Multimodal Models (LMMs) to interpret and answer questions based on medical images. However, the reliance on Supervised…
The coronary artery disease (CAD) involves narrowing and damaging the major blood vessels has become the most life threating disease in the world especially in south Asian reason. Although outstanding medical facilities are available in…
We address the problem of parameter identification for the standard pharmacokinetic/pharmacodynamic (PK/PD) model for anesthetic drugs. Our main contribution is the development of a global optimization method that guarantees finding the…
Rheumatoid arthritis (RA) is an autoimmune condition caused when patients' immune system mistakenly targets their own tissue. Machine learning (ML) has the potential to identify patterns in patient electronic health records (EHR) to…
Background: Patient recruitment in clinical trials is hindered by complex eligibility criteria and labor-intensive chart reviews. Prior research using text-only models have struggled to address this problem in a reliable and scalable way…
Diabetic retinopathy (DR) is one of the leading causes of blindness in the working-age population of developed countries, caused by a side effect of diabetes that reduces the blood supply to the retina. Deep neural networks have been widely…
Identification of abnormalities in red blood cells (RBC) is key to diagnosing a range of medical conditions from anaemia to liver disease. Currently this is done manually, a time-consuming and subjective process. This paper presents an…
The diagnostic accuracy and subjectivity of existing Knee Osteoarthritis (OA) ordinal grading systems has been a subject of on-going debate and concern. Existing automated solutions are trained to emulate these imperfect systems, whilst…
Electronic medical records (EMR) contain longitudinal information about patients that can be used to analyze outcomes. Typically, studies on EMR data have worked with established variables that have already been acknowledged to be…
We develop a prediction-based prescriptive model for learning optimal personalized treatments for patients based on their Electronic Health Records (EHRs). Our approach consists of: (i) predicting future outcomes under each possible therapy…
Areas where Artificial Intelligence (AI) & related fields are finding their applications are increasing day by day, moving from core areas of computer science they are finding their applications in various other domains.In recent times…