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Large language models (LLMs) have demonstrated notable potential in medical applications, yet they face substantial challenges in handling complex real-world clinical diagnoses using conventional prompting methods. Current prompt…

Artificial Intelligence · Computer Science 2026-03-02 Wenliang Li , Rui Yan , Xu Zhang , Li Chen , Hongji Zhu , Jing Zhao , Junjun Li , Mengru Li , Wei Cao , Zihang Jiang , Wei Wei , Kun Zhang , Shaohua Kevin Zhou

In recent years, significant progress has been made in the field of learning from positive and unlabeled examples (PU learning), particularly in the context of advancing image and text classification tasks. However, applying PU learning to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-08 Yan Zhang , Chun Li , Zhaoxia Liu , Ming Li

Background and objective: Diabetes is a chronic pathology which is affecting more and more people over the years. It gives rise to a large number of deaths each year. Furthermore, many people living with the disease do not realize the…

Disease risk prediction has attracted increasing attention in the field of modern healthcare, especially with the latest advances in artificial intelligence (AI). Electronic health records (EHRs), which contain heterogeneous patient…

Artificial Intelligence · Computer Science 2022-01-19 Shuai Niu , Qing Yin , Yunya Song , Yike Guo , Xian Yang

Red blood cells are highly deformable and present in various shapes. In blood cell disorders, only a subset of all cells is morphologically altered and relevant for the diagnosis. However, manually labeling of all cells is laborious,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-24 Ario Sadafi , Asya Makhro , Anna Bogdanova , Nassir Navab , Tingying Peng , Shadi Albarqouni , Carsten Marr

Diabetic retinopathy (DR) grading is crucial in determining the adequate treatment and follow up of patients, but the screening process can be tiresome and prone to errors. Deep learning approaches have shown promising performance as…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Teresa Araújo , Guilherme Aresta , Luís Mendonça , Susana Penas , Carolina Maia , Ângela Carneiro , Ana Maria Mendonça , Aurélio Campilho

This study investigates how machine learning (ML) models can predict hospital readmissions for diabetic patients fairly and accurately across different demographics (age, gender, race). We compared models like Deep Learning, Generalized…

Machine Learning · Computer Science 2024-03-29 Zainab Al-Zanbouri , Gauri Sharma , Shaina Raza

Chemotherapy dose optimization can be formulated as a dynamic treatment regime, requiring sequential decisions under uncertainty that must balance tumor suppression against toxicity. However, most reinforcement learning approaches assume…

Machine Learning · Computer Science 2026-05-05 Firas Mohamed Elamine Kiram , Imane Youkana , Rachida Saouli , Gian Antonio Susto , Laid Kahloul

Harmonizing medication data across Electronic Health Record (EHR) systems is a persistent barrier to monitoring medications for opioid use disorder (MOUD). In heterogeneous EHR systems, key prescription attributes are scattered across…

Artificial Intelligence · Computer Science 2025-10-27 Zhe Fei , Mehmet Yigit Turali , Shreyas Rajesh , Xinyang Dai , Huyen Pham , Pavan Holur , Yuhui Zhu , Larissa Mooney , Yih-Ing Hser , Vwani Roychowdhury

Repeated longitudinal measurements are commonly used to model long-term disease progression, and timing and number of assessments per patient may vary, leading to irregularly spaced and sparse data. Longitudinal trajectories may exhibit…

Despite rare diseases affecting 1 in 10 Americans, their differential diagnosis remains challenging. Due to their impressive recall abilities, large language models (LLMs) have been recently explored for differential diagnosis. Existing…

Artificial Intelligence · Computer Science 2026-01-21 Zilal Eiz AlDin , John Wu , Jeffrey Paul Fung , Jennifer King , Mya Watts , Lauren ONeill , Adam Richard Cross , Jimeng Sun

Hypertrophic cardiomyopathy (HCM) and cardiac amyloidosis (CA) are both heart conditions that can progress to heart failure if untreated. They exhibit similar echocardiographic characteristics, often leading to diagnostic challenges. This…

Image and Video Processing · Electrical Eng. & Systems 2024-04-26 Bo Peng , Xiaofeng Li , Xinyu Li , Zhenghan Wang , Hui Deng , Xiaoxian Luo , Lixue Yin , Hongmei Zhang

International Classification of Diseases(ICD) is an authoritative health care classification system of different diseases and conditions for clinical and management purposes. Considering the complicated and dedicated process to assign…

Computation and Language · Computer Science 2022-01-13 Haoran Shi , Pengtao Xie , Zhiting Hu , Ming Zhang , Eric P. Xing

Attention deficit hyperactivity disorder (ADHD) is one of the common neurodevelopmental disorders in children. This paper presents an automated approach for ADHD detection using the proposed entropy difference (EnD)- based encephalogram…

Signal Processing · Electrical Eng. & Systems 2024-04-16 Shishir Maheshwari , Kandala N V P S Rajesh , Vivek Kanhangad , U Rajendra Acharya , T Sunil Kumar

The detection of cardiovascular diseases (CVD) using machine learning techniques represents a significant advancement in medical diagnostics, aiming to enhance early detection, accuracy, and efficiency. This study explores a comparative…

Machine Learning · Computer Science 2024-05-28 Dayana K , S. Nandini , Sanjjushri Varshini R

Chronic Kidney Disease (CKD) affects millions of people worldwide, yet its early detection remains challenging, especially in outpatient settings where laboratory-based renal biomarkers are often unavailable. In this work, we investigate…

Detection of blood cells in microscopic images has become a major focus of medical image analysis, playing a crucial role in gaining valuable insights into a patient's health. Manual blood cell checks for disease detection are known to be…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Ahmed Endris Hasen , Yang Shangming , Chiagoziem C. Ukwuoma , Biniyam Gashaw , Abel Zenebe Yutra

Continuous monitoring of blood pressure (BP) and hemodynamic parameters such as peripheral resistance (R) and arterial compliance (C) are critical for early vascular dysfunction detection. While photoplethysmography (PPG) wearables has…

Medical Physics · Physics 2025-12-12 Yaowen Zhang , Libera Fresiello , Peter H. Veltink , Dirk W. Donker , Ying Wang

Lumbar disc herniation (LDH) is a common musculoskeletal disease that requires magnetic resonance imaging (MRI) for effective clinical management. However, the interpretation of MRI images heavily relies on the expertise of radiologists,…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Lingrui Zhang , Liang Guo , Xiao An , Feng Lin , Binlong Zheng , Jiankun Wang , Zhirui Li

Leukemia is the 10th most frequently diagnosed cancer and one of the leading causes of cancer-related deaths worldwide. Realistic analysis of leukemia requires white blood cell (WBC) localization, classification, and morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Abdul Rehman , Talha Meraj , Aiman Mahmood Minhas , Ayisha Imran , Mohsen Ali , Waqas Sultani , Mubarak Shah
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