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Recently developed methods for rapid continuous volumetric two-photon microscopy facilitate the observation of neuronal activity in hundreds of individual neurons and changes in blood flow in adjacent blood vessels across a large volume of…

Image and Video Processing · Electrical Eng. & Systems 2020-01-16 Shir Gur , Lior Wolf , Lior Golgher , Pablo Blinder

We develop a framework for analyzing multivariate time series using topological data analysis (TDA) methods. The proposed methodology involves converting the multivariate time series to point cloud data, calculating Wasserstein distances…

Algebraic Topology · Mathematics 2020-12-29 Chengyuan Wu , Carol Anne Hargreaves

Topological data analysis (TDA) allows us to explore the topological features of a dataset. Among topological features, lower dimensional ones have recently drawn the attention of practitioners in mathematics and statistics due to their…

Statistics Theory · Mathematics 2023-09-26 Hengrui Luo , Steve N. MacEachern , Mario Peruggia

Various structures in human physiology follow a treelike morphology, which often expresses complexity at very fine scales. Examples of such structures are intrathoracic airways, retinal blood vessels, and hepatic blood vessels. Large…

Image and Video Processing · Electrical Eng. & Systems 2022-09-23 Hao Li , Zeyu Tang , Yang Nan , Guang Yang

Topological data analysis (TDA) offers novel mathematical tools for deep learning. Inspired by Carlsson et al., this study designs topology-aware convolutional kernels that significantly improve speech recognition networks. Theoretically,…

Machine Learning · Computer Science 2025-05-28 Zhiwang Yu

Vessel tracing by modeling vascular structures in 3D medical images with centerlines and radii can provide useful information for vascular health. Existing algorithms have been developed but there are certain persistent problems such as…

Image and Video Processing · Electrical Eng. & Systems 2021-07-20 Li Chen , Wenjin Liu , Niranjan Balu , Mahmud Mossa-Basha , Thomas S. Hatsukami , Jenq-Neng Hwang , Chun Yuan

In this work we study the topological properties of temporal hypergraphs. Hypergraphs provide a higher dimensional generalization of a graph that is capable of capturing multi-way connections. As such, they have become an integral part of…

Computational Geometry · Computer Science 2023-02-07 Audun Myers , Cliff Joslyn , Bill Kay , Emilie Purvine , Gregory Roek , Madelyn Shapiro

Topological Data Analysis (TDA) is a novel, and relatively new approach to analysing high-dimensional data sets. It does this by focussing on global properties like the shape and connectivity of the data giving it a significant advantage…

Instrumentation and Methods for Astrophysics · Physics 2019-04-26 Jeff Murugan , Duncan Robertson

Topological Data Analysis (TDA), an emerging field in investment sciences, harnesses mathematical methods to extract data features based on shape, offering a promising alternative to classical portfolio selection methodologies. We utilize…

Portfolio Management · Quantitative Finance 2026-01-08 Anubha Goel , Amita Sharma , Juho Kanniainen

Persistent Homology is a powerful tool in Topological Data Analysis (TDA) to capture topological properties of data succinctly at different spatial resolutions. For graphical data, shape, and structure of the neighborhood of individual data…

Social and Information Networks · Computer Science 2018-11-12 Sumit Bhatia , Bapi Chatterjee , Deepak Nathani , Manohar Kaul

Topological data analysis (TDA) detects geometric structure in biological data. However, many TDA algorithms are memory intensive and impractical for massive datasets. Here, we introduce a statistical protocol that reduces TDA's memory…

Quantitative Methods · Quantitative Biology 2025-09-05 Andrew J. Stier , Naichen Shi , Raed Al Kontar , Chad Giusti , Marc G. Berman

Topological data analysis (TDA), as a relatively recent approach, has demonstrated great potential in capturing the intrinsic and robust structural features of complex data. While persistent homology, as a core tool of TDA, focuses on…

Combinatorics · Mathematics 2025-11-11 Jing-Wen Gao , Yunan He , Jian Liu

Shape analysis and classification are popular methods for biologists, biophysicists and mathematicians investigating relationships between object function and form. Classic shape descriptors, such as sphericity, can be powerful but may be…

Quantitative Methods · Quantitative Biology 2025-02-21 Allyson Quinn Ryan , Johannes Soltwedel , Carl D. Modes

Topological data analysis (TDA) is a relatively new field that is gaining rapid adoption due to its robustness and ability to effectively describe complex datasets by quantifying geometric information. In imaging contexts, TDA typically…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Aaryam Sharma

The leaves of angiosperms contain highly complex venation networks consisting of recursively nested, hierarchically organized loops. We describe a new phenotypic trait of reticulate vascular networks based on the topology of the nested…

Quantitative Methods · Quantitative Biology 2016-06-23 Henrik Ronellenfitsch , Jana Lasser , Douglas C. Daly , Eleni Katifori

The structure of real-world networks is usually difficult to characterize owing to the variation of topological scales, the nondyadic complex interactions, and the fluctuations in the network. We aim to address these problems by introducing…

Social and Information Networks · Computer Science 2019-09-25 Quoc Hoan Tran , Van Tuan Vo , Yoshihiko Hasegawa

Despite significant advances in the field of deep learning in applications to various fields, explaining the inner processes of deep learning models remains an important and open question. The purpose of this article is to describe and…

Machine Learning · Computer Science 2022-04-20 German Magai , Anton Ayzenberg

Understanding the topological characteristics of data is important to many areas of research. Recent work has demonstrated that synthetic 4D image-type data can be useful to train 4D convolutional neural network models to see topological…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Khalil Mathieu Hannouch , Stephan Chalup

We present the application of topological data analysis (TDA) to study unweighted complex networks via their persistent homology. By endowing appropriate weights that capture the inherent topological characteristics of such a network, we…

Discrete Mathematics · Computer Science 2021-02-03 Indrava Roy , Sudharsan Vijayaraghavan , Sarath Jyotsna Ramaia , Areejit Samal

We introduce a novel framework for learning vector representations of tree-structured geometric data focusing on 3D vascular networks. Our approach employs two sequentially trained Transformer-based autoencoders. In the first stage, the…

Image and Video Processing · Electrical Eng. & Systems 2025-06-16 James Batten , Michiel Schaap , Matthew Sinclair , Ying Bai , Ben Glocker