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Soft gels, formed via the self-assembly of particulate organic materials, exhibit intricate multi-scale structures that provides them with flexibility and resilience when subjected to external stresses. This work combines molecular…

Soft Condensed Matter · Physics 2024-04-05 Alexander Smith , Gavin J. Donley , Emanuela Del Gado , Victor M. Zavala

The transformation of the regular vasculature in normal tissue into a highly inhomogeneous tumor specific capillary network is described by a theoretical model incorporating tumor growth, vessel cooption, neo-vascularization, vessel…

Tissues and Organs · Quantitative Biology 2016-09-08 K. Bartha , H. Rieger

Topological Data Analysis (TDA) has emerged as a powerful framework for extracting robust, multiscale, and interpretable features from complex molecular data for artificial intelligence (AI) modeling and topological deep learning (TDL).…

Biomolecules · Quantitative Biology 2025-09-23 JunJie Wee , Jian Jiang

Topological Data Analysis (TDA) allows us to extract powerful topological and higher-order information on the global shape of a data set or point cloud. Tools like Persistent Homology or the Euler Transform give a single complex description…

Algebraic Topology · Mathematics 2025-11-04 Vincent P. Grande , Michael T. Schaub

Topological Data Analysis (TDA) is a recent and growing branch of statistics devoted to the study of the shape of the data. In this work we investigate the predictive power of TDA in the context of supervised learning. Since topological…

Machine Learning · Statistics 2017-09-22 Tullia Padellini , Pierpaolo Brutti

A central challenge in hydrodynamic turbulence is identifying precisely when, and at which length scales, strong turbulent fluctuations (STFs) emerge and develop into intermittent events, which are often obscured by conventional statistical…

Angiogenesis is the process by which blood vessels form from pre-existing vessels. It plays a key role in many biological processes, including embryonic development and wound healing, and contributes to many diseases including cancer and…

Quantitative Methods · Quantitative Biology 2021-09-15 John T. Nardini , Bernadette J. Stolz , Kevin B. Flores , Heather A. Harrington , Helen M. Byrne

Topology is critical in tubular structures such as blood vessels, nerve fibers, and road networks, where connectivity and loop structure govern downstream functional analysis. Vision-Language Models (VLMs) are promising candidates for…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Meilong Xu , Qingqiao Hu , Xiaoling Hu , Shahira Abousamra , Xin Yu , Weimin Lyu , Kehan Qi , Dimitris Samaras , Chao Chen

In the past decade, topological data analysis (TDA) has emerged as a powerful approach in data science. The main technique in TDA is persistent homology, which tracks topological invariants over the filtration of point cloud data using…

Geometric Topology · Mathematics 2023-11-23 Li Shen , Hongsong Feng , Fengling Li , Fengchun Lei , Jie Wu , Guo-Wei Wei

Topological data analysis (TDA) has become a powerful approach over the last twenty years, mainly due to its ability to capture the shape and the geometry inherent in the data. Persistence homology, which is a particular tool in TDA, has…

Neurons and Cognition · Quantitative Biology 2024-01-12 Anass B. El-Yaagoubi , Shuhao Jiao , Moo K. Chung , Hernando Ombao

Despite significant advances in the field of deep learning in ap-plications to various areas, an explanation of the learning pro-cess of neural network models remains an important open ques-tion. The purpose of this paper is a comprehensive…

Machine Learning · Computer Science 2023-06-07 German Magai

Topological Data Analysis (TDA) is a rising field of computational topology in which the topological structure of a data set can be observed by persistent homology. By considering a sequence of sublevel sets, one obtains a filtration that…

Methodology · Statistics 2020-03-17 Yu-Min Chung , William Cruse , Austin Lawson

Machine learning models for repeated measurements are limited. Using topological data analysis (TDA), we present a classifier for repeated measurements which samples from the data space and builds a network graph based on the data topology.…

Machine Learning · Computer Science 2019-04-08 Henri Riihimäki , Wojciech Chachólski , Jakob Theorell , Jan Hillert , Ryan Ramanujam

Topological Data Analysis (TDA) is increasingly crucial in investigating the shape of complex data structures across scientific fields, particularly in neuroscience and finance. This study delves into persistent homology, a TDA component…

Physics and Society · Physics 2024-09-17 Roel Gisolf , Fernando A. N. Santos , Felix Wierstra

Developing reliable methods to discriminate different transient brain states that change over time is a key neuroscientific challenge in brain imaging studies. Topological data analysis (TDA), a novel framework based on algebraic topology,…

Neurons and Cognition · Quantitative Biology 2023-12-19 Moo K. Chung , Soumya Das , Hernando Ombao

We introduce a very general approach to the analysis of signals from their noisy measurements from the perspective of Topological Data Analysis (TDA). While TDA has emerged as a powerful analytical tool for data with pronounced topological…

Signal Processing · Electrical Eng. & Systems 2025-07-29 Juan Manuel Miramont , Kin Aun Tan , Soumendu Sundar Mukherjee , Rémi Bardenet , Subhroshekhar Ghosh

We introduce a novel, data-driven topological data analysis (TDA) approach for embedding brain networks into a lower-dimensional space in quantifying the dynamics of temporal lobe epilepsy (TLE) obtained from resting-state functional…

In this paper we develop a novel Topological Data Analysis (TDA) approach for studying graph representations of time series of dynamical systems. Specifically, we show how persistent homology, a tool from TDA, can be used to yield a…

Chaotic Dynamics · Physics 2020-01-28 Audun Myers , Elizabeth Munch , Firas A. Khasawneh

Despite the remarkable accuracies attained by machine learning classifiers to separate complex datasets in a supervised fashion, most of their operation falls short to provide an informed intuition about the structure of data, and, what is…

Machine Learning · Computer Science 2023-03-09 Aina Ferrà , Gloria Cecchini , Fritz-Pere Nobbe Fisas , Carles Casacuberta , Ignasi Cos

Topological Data Analysis (TDA) provides tools to describe the shape of data, but integrating topological features into deep learning pipelines remains challenging, especially when preserving local geometric structure rather than…

Machine Learning · Computer Science 2026-04-21 Elena Xinyi Wang , Arnur Nigmetov , Dmitriy Morozov