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A probabilistic Boolean network (PBN) is a discrete-time system composed of a collection of Boolean networks between which the PBN switches in a stochastic manner. This paper focuses on the study of quotients of PBNs. Given a PBN and an…

Optimization and Control · Mathematics 2021-08-02 Rui Li , Qi Zhang , Tianguang Chu

Regulatory networks (RNs) are a well-accepted modelling formalism in computational systems biology. The control of RNs is currently receiving a lot of attention because it provides a computational basis for cell reprogramming -- an…

Systems and Control · Electrical Eng. & Systems 2022-03-01 Luboš Brim , Samuel Pastva , David Šafránek , Eva Šmijáková

Motivated by the applications, a class of optimal control problems is investigated, where the goal is to influence the behavior of a given population through another controlled one interacting with the first. Diffusive terms accounting for…

Optimization and Control · Mathematics 2023-03-10 Stefano Almi , Marco Morandotti , Francesco Solombrino

Sequential Model-based Bayesian Optimization has been successful-ly applied to several application domains, characterized by complex search spaces, such as Automated Machine Learning and Neural Architecture Search. This paper focuses on…

Systems and Control · Electrical Eng. & Systems 2020-03-10 Antonio Candelieri , Bruno Galuzzi , Ilaria Giordani , Francesco Archetti

It has been shown that self-triggered control has the ability to reduce computational loads and deal with the cases with constrained resources by properly setting up the rules for updating the system control when necessary. In this paper,…

Systems and Control · Electrical Eng. & Systems 2020-07-07 Min Meng , Gaoxi Xiao , Daizhan Cheng

We study the target control of asynchronous Boolean networks, to identify efficacious interventions that can drive the dynamics of a given Boolean network from any initial state to the desired target attractor. Based on the application…

Systems and Control · Electrical Eng. & Systems 2021-01-05 Cui Su , Jun Pang

The co-evolution of network topology and dynamics is studied in an evolutionary Boolean network model that is a simple model of gene regulatory network. We find that a critical state emerges spontaneously resulting from interplay between…

Statistical Mechanics · Physics 2007-05-23 Min Liu , Kevin E. Bassler

This paper deals with controllability of dynamical networks. It is often unfeasible or unnecessary to fully control large-scale networks, which motivates the control of a prescribed subset of agents of the network. This specific form of…

Optimization and Control · Mathematics 2016-08-09 Henk J. van Waarde , M. Kanat Camlibel , Harry L. Trentelman

Biological processes, including cell differentiation, organism development, and disease progression, can be interpreted as attractors (fixed points or limit cycles) of an underlying networked dynamical system. In this paper, we study the…

Systems and Control · Computer Science 2017-01-20 Andrew Clark , Phillip Lee , Basel Alomair , Linda Bushnell , Radha Poovendran

A fundamental concept in control theory is that of controllability, where any system state can be reached through an appropriate choice of control inputs. Indeed, a large body of classical and modern approaches are designed for controllable…

Optimization and Control · Mathematics 2022-06-13 Yonathan Efroni , Sham Kakade , Akshay Krishnamurthy , Cyril Zhang

The semilinear beam equation with impulses, memory and delay is considered. We obtain the approximate controllability. This is done by employing a technique that avoids fixed point theorems and pulling back the control solution to a fixed…

Optimization and Control · Mathematics 2017-11-15 Alexander Carrasco , Cristi Guevara , Hugo Leiva

The control of complex systems is an ongoing challenge of complexity research. Recent advances using concepts of structural control deduce a wide range of control related properties from the network representation of complex systems. Here,…

Statistical Mechanics · Physics 2013-12-31 Márton Pósfai , Philipp Hövel

This paper considers the problem of determining an optimal control action based on observed data. We formulate the problem assuming that the system can be modelled by a nonlinear state-space model, but where the model parameters, state and…

Optimization and Control · Mathematics 2021-07-02 Johannes N. Hendriks , James R. Z. Holdsworth , Adrian G. Wills , Thomas B. Schon , Brett Ninness

A Boolean network is a finite state discrete time dynamical system. At each step, each variable takes a value from a binary set. The value update rule for each variable is a local function which depends only on a selected subset of…

Dynamical Systems · Mathematics 2017-08-10 Zuguang Gao , Xudong Chen , Tamer Başar

We survey in this article the connections between Machine Learning and Control Theory. Control Theory provide useful concepts and tools for Machine Learning. Conversely Machine Learning can be used to solve large control problems. In the…

Machine Learning · Computer Science 2020-06-11 Alain Bensoussan , Yiqun Li , Dinh Phan Cao Nguyen , Minh-Binh Tran , Sheung Chi Phillip Yam , Xiang Zhou

Social science studies dealing with control in networks typically resort to heuristics or describing the static control distribution. Optimal policies, however, require interventions that optimize control over a socioeconomic network…

Social and Information Networks · Computer Science 2021-08-24 Jannes Nys , Milan van den Heuvel , Koen Schoors , Bruno Merlevede

Estimating the influence that individual nodes have on one another in a Boolean network is essential to predict and control the system's dynamical behavior, for example, detecting key therapeutic targets to control pathways in models of…

Physics and Society · Physics 2023-11-02 Thomas Parmer , Filippo Radicchi

We present a method for optimal control with respect to a linear cost function for positive linear systems with coupled input constraints. We show that the optimal cost function and resulting sparse state feedback for these systems can be…

Optimization and Control · Mathematics 2023-11-07 David Ohlin , Emma Tegling , Anders Rantzer

Dynamical systems theory and complexity science provide powerful tools for analysing artificial agents and robots. Furthermore, they have been recently proposed also as a source of design principles and guidelines. Boolean networks are a…

Artificial Intelligence · Computer Science 2015-03-18 Andrea Roli , Mattia Manfroni , Carlo Pinciroli , Mauro Birattari

A properly designed controller can help improve the quality of experimental measurements or force a dynamical system to follow a completely new time-evolution path. Recent developments in deep reinforcement learning have made steep advances…

Statistical Mechanics · Physics 2025-02-26 Ruslan Mukhamadiarov