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New insights into phase separation in colloidal suspensions are provided via a new dynamical theory based on the Polydisperse Lattice-Gas model. The model gives a simplified description of polydisperse colloids, incorporating a hard-core…

Soft Condensed Matter · Physics 2017-08-03 Pablo de Castro , Peter Sollich

In biology, ligand mediated transitions (LMT), where the binding of a molecular ligand onto the binding site of a receptor molecule leads to a well-defined change in the conformation of the receptor, are often referred to as 'the second…

Aqueous two-phase systems (ATPSs), that is, phase-separating solutions of water soluble but mutually immiscible molecular species, offer fascinating prospects for selective partitioning, purification, and extraction. Here, we formulate a…

Soft Condensed Matter · Physics 2023-11-29 Alberto Scacchi , Carlo Rigoni , Mikko Haataja , Jaakko V. I. Timonen , Maria Sammalkorpi

The formulation of a model for the evolution of the flow of a solid-liquid mixture (coal-water) in a horizontal pipeline with partial phase separation is the aim of this work. Problems of instabilities due to complex eigenvalues, observed…

Fluid Dynamics · Physics 2010-12-14 Alessandro Speranza

In conflict with standard notions of thermodynamics, mesoscopically-sized inclusions (``clusters'') of a solute-rich liquid have been observed in equilibrated solutions of proteins and other molecules. According to a complexation scenario…

Soft Condensed Matter · Physics 2025-09-11 Ilya Davydov , Vassiliy Lubchenko

We present a ``coarse molecular dynamics'' approach and apply it to studying the kinetics and thermodynamics of a peptide fragment dissolved in water. Short bursts of appropriately initialized simulations are used to infer the deterministic…

Chemical Physics · Physics 2009-11-07 Gerhard Hummer , Ioannis G. Kevrekidis

Recent experimental realizations of liquid-liquid phase separation of active liquid crystals have offered an insight into the interaction between phase separation, ubiquitous in soft matter and biology, and chaotic active flows. In this…

Soft Condensed Matter · Physics 2025-04-23 Paarth Gulati , Fernando Caballero , M. Cristina Marchetti

Liquid-liquid phase separation of liquids exhibiting interconversion between alternative states has been proposed as an underlying mechanism for fluid polyamorphism, and may be of relevance to protein function and intracellular…

Statistical Mechanics · Physics 2021-12-08 Betul Uralcan , Thomas J. Longo , Mikhail A. Anisimov , Frank H. Stillinger , Pablo G. Debenedetti

The protein-polysaccharide combinations that lead to electrostatic complex and coacervates formation are the object of extensive research using both layer-by-layer and mixed emulsion approaches. The protein-polysaccharide conjugates…

Soft Condensed Matter · Physics 2022-01-25 Luigi Gentile

Multicomponent multiphase reactive transport processes with dissolution-precipitation are widely encountered in energy and environment systems. A pore-scale two-phase multi-mixture model based on the lattice Boltzmann method (LBM) is…

Fluid Dynamics · Physics 2015-04-09 Li Chen , Qinjun Kang , Qing Tang , Bruce A. Robinson , Ya-Ling He , Wen-Quan Tao

Differences in activities in colloidal particles are sufficient to drive phase separation between active and passive (or less active) particles, even if they have only excluded volume interactions. In this paper, we study the phase…

Soft Condensed Matter · Physics 2020-05-27 Efe Ilker , Jean-François Joanny

A combination of cellular contractility and active phase separation in cell-matrix composites is thought to be an enabler of spatiotemporal patterning in multicellular tissues across scales, from somitogenesis to cartilage condensation. To…

Soft Condensed Matter · Physics 2022-11-21 Sifan Yin , L Mahadevan

Water/glycerol mixtures are common for experiments with biomacromolecules at cryogenic temperatures due to their vitrification properties. Above the glass transition temperature, they undergo liquid-liquid phase separation. Using the novel…

Soft Condensed Matter · Physics 2025-09-11 Sergei Kuzin , Maxim Yulikov

We review understanding of kinetics of fluid phase separation in various space dimensions. Morphological differences, percolating or disconnected, based on overall composition in a binary liquid or density in a vapor-liquid system, have…

Statistical Mechanics · Physics 2020-06-05 Subir K. Das , Sutapa Roy , Jiarul Midya

The determination of phase behavior and, in particular, the nature of phase transitions in two-dimensional systems is often clouded by finite size effects and by access to the appropriate thermodynamic regime. We address these issues using…

Soft Condensed Matter · Physics 2019-10-02 Shaghayegh Darjani , Joel Koplik , Sanjoy Banerjee , Vincent Pauchard

The equilibrium phase behaviour of hard spheres with size polydispersity is studied theoretically. We solve numerically the exact phase equilibrium equations that result from accurate free energy expressions for the fluid and solid phases,…

Soft Condensed Matter · Physics 2007-05-23 M. Fasolo , P. Sollich

In recent years, a second fluid-fluid phase transition has been reported in several materials at pressures far above the usual liquid-gas phase transition. In this paper, we introduce a new model of this behavior based on the Lennard-Jones…

Statistical Mechanics · Physics 2009-11-07 H. K. Lee , R. H. Swendsen

The liquid-gas transition of an electroneutral mixture of oppositely charged colloids, studied by Monte Carlo simulations, is found in the low temperature -- low density region. The critical temperature shows a non-monotonous behavior as a…

Liquid-liquid and liquid-vapor coexistence regions of various water models were determined by MC simulations of isotherms of density fluctuation restricted systems and by Gibbs ensemble MC simulations. All studied water models show multiple…

Statistical Mechanics · Physics 2009-11-11 Ivan Brovchenko , Alfons Geiger , Alla Oleinikova

When a liquid mixture is subjected to external electric fields, ionic screening leads to field gradients. We point out that if the mixture is initially in the homogeneous phase, this screening can bring about a robust phase-separation…

Soft Condensed Matter · Physics 2009-11-11 Yoav Tsori , Ludwik Leibler