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Quantitative susceptibility mapping (QSM) is a valuable magnetic resonance imaging (MRI) contrast mechanism that has demonstrated broad clinical applications. However, the image reconstruction of QSM is challenging due to its ill-posed…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Yang Gao , Xuanyu Zhu , Bradford A. Moffat , Rebecca Glarin , Alan H. Wilman , G. Bruce Pike , Stuart Crozier , Feng Liu , Hongfu Sun

Quantitative susceptibility mapping (QSM) has been increasingly applied in longitudinal studies of neurodegenerative diseases and aging to assess temporal alterations in brain iron and myelin. The accuracy of such investigations depends on…

Quantitative Methods · Quantitative Biology 2026-05-05 Jiye Kim , Hwihun Jeong , Taechang Kim , Eunseon Jeong , Jinhee Jang , Yangsean Choi , Jongho Lee

Quantitative susceptibility mapping (QSM) is a post-processing technique for deriving tissue magnetic susceptibility distribution from MRI phase measurements. Deep learning (DL) algorithms hold great potential for solving the ill-posed QSM…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Yang Gao , Zhuang Xiong , Shanshan Shan , Yin Liu , Pengfei Rong , Min Li , Alan H Wilman , G. Bruce Pike , Feng Liu , Hongfu Sun

Objective: We propose a method for the reconstruction of parameter-maps in Quantitative Magnetic Resonance Imaging (QMRI). Methods: Because different quantitative parameter-maps differ from each other in terms of local features, we propose…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Andreas Kofler , Kirsten Miriam Kerkering , Laura Göschel , Ariane Fillmer , Cristoph Kolbitsch

Quantitative susceptibility mapping (QSM) is a powerful MRI technique that has shown great potential in quantifying tissue susceptibility in numerous neurological disorders. However, the intrinsic ill-posed dipole inversion problem greatly…

Image and Video Processing · Electrical Eng. & Systems 2019-10-31 Yicheng Chen , Angela Jakary , Sivakami Avadiappan , Christopher P. Hess , Janine M. Lupo

Purpose: Quantitative Susceptibility Mapping (QSM) reconstruction is a challenging inverse problem driven by poor conditioning of the field to susceptibility transformation. State-of-art QSM reconstruction methods either suffer from image…

Medical Physics · Physics 2019-03-14 Juan Liu , Andrew S. Nencka , L. Tugan Muftuler , Brad Swearingen , Robin Karr , Kevin M. Koch

This article provides recommendations for implementing quantitative susceptibility mapping (QSM) for clinical brain research. It is a consensus of the ISMRM Electro-Magnetic Tissue Properties Study Group. While QSM technical development…

Introduction: Quantitative Susceptibility Mapping (QSM) is generally acquired with full brain coverage, even though many QSM brain-iron studies focus on the deep grey matter (DGM) region only. Reducing the spatial coverage to the DGM…

Quantitative Methods · Quantitative Biology 2021-06-02 Xuanyu Zhu , Yang Gao , Feng Liu , Stuart Crozier , Hongfu Sun

In MR fingerprinting (MRF) reconstruction, measured data is pattern-matched to simulated signals to extract quantitative tissue parameters. A critical drawback to this approach is the exponentially increasing compute time for mapping of…

Medical Physics · Physics 2024-07-17 Victoria Y. Yu , Kathryn R. Tringale , Ricardo Otazo , Ouri Cohen

Weakly Supervised Semantic Segmentation (WSSS) relying only on image-level supervision is a promising approach to deal with the need for Segmentation networks, especially for generating a large number of pixel-wise masks in a given dataset.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-21 Bharath Srinivas Prabakaran , Erik Ostrowski , Muhammad Shafique

This paper proposes a novel self-supervised learning method, RELAX-MORE, for quantitative MRI (qMRI) reconstruction. The proposed method uses an optimization algorithm to unroll a model-based qMRI reconstruction into a deep learning…

Biological Physics · Physics 2023-07-26 Wanyu Bian , Albert Jang , Fang Liu

In the human brain, essential iron molecules for proper neurological functioning exist in transferrin (tf) and ferritin (Fe3) forms. However, its unusual increment manifests iron overload, which reacts with hydrogen peroxide. This reaction…

Neurons and Cognition · Quantitative Biology 2022-11-10 Shradha Verma , Tripti Goel , M Tanveer

Quantitative Susceptibility Mapping (QSM) quantifies tissue magnetic susceptibility from magnetic-resonance phase data and plays a crucial role in brain microstructure imaging, iron-deposition assessment, and neurological-disease research.…

Image and Video Processing · Electrical Eng. & Systems 2025-12-11 Xuan Cai , Ruo-Mi Guo , Xiao-Wen Luo , Jing Zhao , Silun Wang , Tao Tan , Yue Liu , Hongbin Han , Mengting Liu

Seismic full waveform inversion (FWI) is a powerful geophysical imaging technique that produces high-resolution subsurface models by iteratively minimizing the misfit between the simulated and observed seismograms. Unfortunately,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-24 Fangshu Yang , Jianwei Ma

Magnetic Resonance Imaging (MRI) represents an important diagnostic modality; however, its inherently slow acquisition process poses challenges in obtaining fully-sampled $k$-space data under motion. In the absence of fully-sampled…

Image and Video Processing · Electrical Eng. & Systems 2024-12-23 George Yiasemis , Nikita Moriakov , Clara I. Sánchez , Jan-Jakob Sonke , Jonas Teuwen

Reconstructing high-quality images from substantially undersampled k-space data for accelerated MRI presents a challenging ill-posed inverse problem. While supervised deep learning has revolutionized this field, it relies heavily on large…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Xinzhe Luo , Yingzhen Li , Chen Qin

Motivation - The test-retest reliability of quantitative susceptibility mapping (QSM) is affected by parameters of the acquisition protocol such as the angulation of acquisition plane with respect to the B0 field direction and spatial…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Shuai Huang , Thomas Denney , Deqiang Qiu

Quantitative phase imaging (QPI) through multi-core fibers (MCFs) has been an emerging in vivo label-free endoscopic imaging modality with minimal invasiveness. However, the computational demands of conventional iterative phase retrieval…

Quantitative phase imaging (QPI) is a label-free technique providing both morphology and quantitative biophysical information in biomedicine. However, applying such a powerful technique to in vivo pathological diagnosis remains challenging.…

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

Computer Vision and Pattern Recognition · Computer Science 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras