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Related papers: Multistability of Small Reaction Networks

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The structure of invariant regions and globally attracting regions is fundamental to understanding the dynamical properties of reaction network models. We describe an explicit construction of the minimal invariant regions and minimal…

Dynamical Systems · Mathematics 2021-10-28 Yida Ding , Abhishek Deshpande , Gheorghe Craciun

We show that weakly reversible mass-action systems can have a continuum of positive steady states, coming from the zeroes of a multivariate polynomial. Moreover, the same is true of systems whose underlying reaction network is reversible…

Molecular Networks · Quantitative Biology 2022-09-14 Balázs Boros , Gheorghe Craciun , Polly Y. Yu

An important invariant of a chemical reaction network is its maximum number of positive steady states. This number, however, is in general difficult to compute. Nonetheless, there is an upper bound on this number -- namely, a network's…

Molecular Networks · Quantitative Biology 2020-12-09 Nida Obatake , Anne Shiu , Dilruba Sofia

Zero-one reaction networks are pivotal to cellular signaling, and establishing the equivalence of such networks represents a foundational computational challenge in the realm of chemical reaction network research. Herein, we propose a…

Molecular Networks · Quantitative Biology 2026-02-03 Yue Jiao , Xiaoxian Tang

We study stationary distributions in the context of stochastic reaction networks. In particular, we are interested in complex balanced reaction networks and reduction of such networks by assuming a set of species (called non-interacting…

Probability · Mathematics 2024-02-06 Linard Hoessly , Carsten Wiuf , Panqiu Xia

We provide a sufficient and necessary condition in terms of the stoichiometric coefficients for a bi-reaction network to admit multistability. Also, this result completely characterizes the bi-reaction networks according to if they admit…

Dynamical Systems · Mathematics 2024-05-09 Yixuan Liang , Xiaoxian Tang , Qian Zhang

A reaction network is a chemical system involving multiple reactions and chemical species. Stochastic models of such networks treat the system as a continuous time Markov chain on the number of molecules of each species with reactions as…

Probability · Mathematics 2007-05-23 Karen Ball , Thomas G. Kurtz , Lea Popovic , Greg Rempala

We consider stochastic reaction networks modeled by continuous-time Markov chains. Such reaction networks often contain many reactions, potentially occurring at different time scales, and have unknown parameters (kinetic rates, total…

Probability · Mathematics 2023-02-20 Linard Hoessly , Carsten Wiuf

The standard analysis of reaction networks based on deterministic rate equations fails in confined geometries, commonly encountered in fields such as astrochemistry, thin film growth and cell biology. In these systems the small reactant…

Other Condensed Matter · Physics 2007-05-23 Ofer Biham , Joachim Krug , Azi Lipshtat , Thomas Michely

Reaction networks (RNs) comprise a set $X$ of species and a set $\mathscr{R}$ of reactions $Y\to Y'$, each converting a multiset of educts $Y\subseteq X$ into a multiset $Y'\subseteq X$ of products. RNs are equivalent to directed…

Molecular Networks · Quantitative Biology 2022-01-06 Stefan Müller , Christoph Flamm , Peter F. Stadler

Mass-action kinetics is frequently used in systems biology to model the behaviour of interacting chemical species. Many important dynamical properties are known to hold for such systems if they are weakly reversible and have a low…

Dynamical Systems · Mathematics 2014-07-15 Matthew D. Johnston , David Siegel , Gábor Szederkényi

Chemical reaction network theory is a field of applied mathematics concerned with modeling chemical systems, and can be used in other contexts such as in systems biology to study cellular signaling pathways or epidemiology to study the…

Algebraic Geometry · Mathematics 2024-06-17 Maize Curiel , Elise Farr , Galileo Fries , Luis David García Puente , Julian Hutchins , Vuong Nguyen Hoang

We study the discrete Gierer-Meinhardt model of reaction-diffusion on three different types of networks: regular, random and scale-free. The model dynamics lead to the formation of stationary Turing patterns in the steady state in certain…

Statistical Mechanics · Physics 2009-11-10 Subhasis Banerjee , Shrestha Basu Mallik , Indrani Bose

In this article, we take a closer look at the reliability of large minimal networks constructed by repeated compositions of the simplest possible networks. For a given number of devices $n=2^m$ we define the set of all the possible…

Discrete Mathematics · Computer Science 2021-12-14 Vlad-Florin Dragoi , Valeriu Beiu

The problem of achieving consensus in a network of connected systems arises in many science and engineering applications. In contrast to previous works, we focus on the system reactivity, i.e., the initial amplification of the norm of the…

Systems and Control · Electrical Eng. & Systems 2023-06-21 Amirhossein Nazerian , David Phillips , Hernan A. Makse , Francesco Sorrentino

We study the set of output stable configurations of chemical reaction deciders (CRDs). It turns out that CRDs with only bimolecular reactions (which are almost equivalent to population protocols) have a special structure that allows for an…

Computational Complexity · Computer Science 2015-06-16 Robert Brijder

In systems and synthetic biology, much research has focused on the behavior and design of single pathways, while, more recently, experimental efforts have focused on how cross-talk (coupling two or more pathways) or inhibiting molecular…

Dynamical Systems · Mathematics 2019-08-15 Elizabeth Gross , Heather A Harrington , Nicolette Meshkat , Anne Shiu

The nuclear reaction network is usually studied via precise calculation of differential equation sets, and much research interest has been focused on the characteristics of nuclides, such as half-life and size limit. In this paper, however,…

Nuclear Theory · Physics 2016-08-30 Liang Zhu , Yu-Gang Ma , Qu Chen , Ding-Ding Han

We consider the question whether a chemical reaction network preserves the number and stability of its positive steady states upon inclusion of inflow and outflow reactions. Often a model of a reaction network is presented without inflows…

Molecular Networks · Quantitative Biology 2019-12-11 Daniele Cappelletti , Elisenda Feliu , Carsten Wiuf

In this note, we use a result by Harris (1957) to show that there always exists a stationary measure (not necessarily a distribution) on a closed irreducible component of a stochastic reaction network. This measure might not be unique. In…

Molecular Networks · Quantitative Biology 2023-12-14 Carsten Wiuf , Chuang Xu